AutismKB 2.0

Annotation Detail for ADCK4


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Basic Information Top
Gene Symbol:ADCK4 ( FLJ12229 )
Gene Full Name: aarF domain containing kinase 4
Band: 19q13.2
Quick LinksEntrez ID:79934; OMIM: NA; Uniprot ID:ADCK4_HUMAN; ENSEMBL ID: ENSG00000123815; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus4 / 5640127
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma27 / 71755376
non-neoplasia2 / 9725020
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow2 / 4880140
brain10 / 11009899
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph25 / 44270564
lymph node2 / 9161021
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P208400
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.68 ± 0.86
Basal Forebrain3.62 ± 0.47
Basal Part of Pons3.89 ± 1.03
Cerebellar Cortex4.04 ± 0.47
Cerebellar Nuclei3.52 ± 0.44
Claustrum3.58 ± 0.74
Epithalamus3.87 ± 0.83
Frontal Lobe3.53 ± 0.62
Globus Pallidus3.06 ± 0.88
Hypothalamus3.33 ± 0.42
Insula3.46 ± 0.47
Limbic Lobe3.59 ± 0.66
Mesencephalon3.6 ± 0.65
Myelencephalon3.56 ± 0.7
Occipital Lobe3.39 ± 0.66
Parietal Lobe3.61 ± 0.79
Pontine Tegmentum3.45 ± 0.48
Striatum3.51 ± 0.66
Subthalamus3.14 ± 0.64
Temporal Lobe3.64 ± 0.63
Thalamus3.52 ± 0.68
White Matter3.45 ± 0.8
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adck4CBCerebellum3.05
3.52
Adck4CTXCerebral cortex6.43
4.56
Adck4HIPHippocampal region11.35
11.55
Adck4HPFHippocampal formation12.27
11.04
Adck4HYHypothalamus18.03
13.65
Adck4LSXLateral septal complex20.67
13.8
Adck4MBMidbrain2.98
4.07
Adck4MYMedulla4.08
5.44
Adck4OLFOlfactory bulb21.17
15.15
Adck4PPons1.68
1.96
Adck4PALPallidum7.79
5.87
Adck4RHPRetrohippocampal region13.57
10.43
Adck4sAMYStriatum-like amygdalar nuclei27.25
18.3
Adck4STRStriatum6.06
4.22
Adck4STRdStriatum dorsal region1.26
1.17
Adck4STRvStriatum ventral region3.69
2.31
Adck4THThalamus3.21
3.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00082147 15 435 449 HRLCPPPEETYALHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018