AutismKB 2.0

Annotation Detail for WDR76


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Basic Information Top
Gene Symbol:WDR76 ( CDW14,FLJ12973 )
Gene Full Name: WD repeat domain 76
Band: 15q15.3
Quick LinksEntrez ID:79968; OMIM: NA; Uniprot ID:WDR76_HUMAN; ENSEMBL ID: ENSG00000092470; HGNC ID: 25773
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor3 / 17290173
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor9 / 10312787
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal45 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma3 / 4635664
skin tumor3 / 12494924
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow2 / 4880140
brain7 / 11009896
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus3 / 20209148
eye3 / 21105414
heart0 / 896260 
intestine6 / 23447225
kidney6 / 21177728
larynx1 / 2414541
liver10 / 20774348
lung11 / 33697432
lymph0 / 442700 
lymph node6 / 9161065
mammary gland2 / 15327113
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach1 / 9661910
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205519_at
Cell line Expression level Expression bar
721_B_lymphoblasts51.1
Adipocyte11.4
AdrenalCortex14.9
Adrenalgland9.85
Amygdala10.85
Appendix15.6
AtrioventricularNode14.65
BDCA4+_DentriticCells10.85
Bonemarrow11.8
BronchialEpithelialCells10.25
CD105+_Endothelial17.1
CD14+_Monocytes12.6
CD19+_BCells(neg._sel.)12.55
CD33+_Myeloid15.4
CD34+40.05
CD4+_Tcells13.75
CD56+_NKCells14.05
CD71+_EarlyErythroid33.45
CD8+_Tcells11.65
CardiacMyocytes25.2
Caudatenucleus10.35
Cerebellum9.5
CerebellumPeduncles14.7
CiliaryGanglion11.95
CingulateCortex12.5
Colorectaladenocarcinoma11.5
DorsalRootGanglion18.4
FetalThyroid11.45
Fetalbrain11.8
Fetalliver10
Fetallung8.6
GlobusPallidus9.7
Heart18.05
Hypothalamus10.25
Kidney9.9
Leukemia_chronicMyelogenousK-56210.65
Leukemia_promyelocytic-HL-6011.5
Leukemialymphoblastic(MOLT-4)12.3
Liver15.6
Lung12.6
Lymphnode10.2
Lymphoma_burkitts(Daudi)15.25
Lymphoma_burkitts(Raji)16.95
MedullaOblongata10.2
OccipitalLobe10.5
OlfactoryBulb9.3
Ovary9.25
Pancreas9.5
PancreaticIslet12.7
ParietalLobe12.7
Pituitary13.5
Placenta11.55
Pons11.25
PrefrontalCortex12.45
Prostate12.85
Salivarygland9.55
SkeletalMuscle14.75
Skin12
SmoothMuscle12.9
Spinalcord12.6
SubthalamicNucleus11.55
SuperiorCervicalGanglion27.5
TemporalLobe10.9
Testis9.95
TestisGermCell9.4
TestisIntersitial9.95
TestisLeydigCell12.05
TestisSeminiferousTubule10.2
Thalamus12.3
Thymus9.2
Thyroid13.1
Tongue13.65
Tonsil12.8
Trachea9.85
TrigeminalGanglion25.35
Uterus9.2
UterusCorpus12.15
WholeBlood12.25
Wholebrain8.9
colon11.65
pineal_day13.32
pineal_night13.62
retina13.55
small_intestine10.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P129075
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.96 ± 0.99
Basal Forebrain1.52 ± 0.18
Basal Part of Pons1.34 ± 0.45
Cerebellar Cortex1.99 ± 0.64
Cerebellar Nuclei1.84 ± 0.74
Claustrum2.31 ± 0.73
Epithalamus1.43 ± 0.73
Frontal Lobe1.37 ± 0.64
Globus Pallidus1.8 ± 0.54
Hypothalamus1.67 ± 0.71
Insula1.64 ± 0.66
Limbic Lobe1.57 ± 0.66
Mesencephalon1.71 ± 0.71
Myelencephalon1.66 ± 0.65
Occipital Lobe1.71 ± 0.58
Parietal Lobe1.66 ± 0.76
Pontine Tegmentum1.59 ± 0.68
Striatum1.47 ± 0.54
Subthalamus1.7 ± 0.62
Temporal Lobe1.49 ± 0.61
Thalamus1.52 ± 0.58
White Matter1.84 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr76CBCerebellum27.15
33.72
Wdr76CTXCerebral cortex29.25
20.64
Wdr76HIPHippocampal region18.63
19.57
Wdr76HPFHippocampal formation23.46
21.45
Wdr76HYHypothalamus11.18
8.38
Wdr76LSXLateral septal complex3.62
3.51
Wdr76MBMidbrain9.46
8.02
Wdr76MYMedulla26.95
27.25
Wdr76OLFOlfactory bulb46.73
38.13
Wdr76PPons21.48
20.2
Wdr76PALPallidum17.16
13.85
Wdr76RHPRetrohippocampal region31.41
24.01
Wdr76sAMYStriatum-like amygdalar nuclei58.74
44.25
Wdr76STRStriatum20.83
15.13
Wdr76STRdStriatum dorsal region18.34
13.59
Wdr76STRvStriatum ventral region24.31
15.42
Wdr76THThalamus16.15
11.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00496071 18 105 122 AESTLQNSSSAVHTESNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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