AutismKB 2.0

Annotation Detail for GREB1L


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Basic Information Top
Gene Symbol:GREB1L ( C18orf6,KIAA1772 )
Gene Full Name: growth regulation by estrogen in breast cancer-like
Band: 18q11.1-q11.2
Quick LinksEntrez ID:80000; OMIM: NA; Uniprot ID:GRB1L_HUMAN; ENSEMBL ID: ENSG00000141449; HGNC ID: 31042
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal43 / 336030712
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220340_at
Cell line Expression level Expression bar
721_B_lymphoblasts3.9
Adipocyte3.35
AdrenalCortex3.2
Adrenalgland2.7
Amygdala3.3
Appendix3.4
AtrioventricularNode2.55
BDCA4+_DentriticCells3.45
Bonemarrow3.3
BronchialEpithelialCells3.05
CD105+_Endothelial3.1
CD14+_Monocytes3.3
CD19+_BCells(neg._sel.)3.3
CD33+_Myeloid3.95
CD34+3.95
CD4+_Tcells3.4
CD56+_NKCells3.7
CD71+_EarlyErythroid2.9
CD8+_Tcells3
CardiacMyocytes3.9
Caudatenucleus2.8
Cerebellum3.45
CerebellumPeduncles3.6
CiliaryGanglion2.15
CingulateCortex3.15
Colorectaladenocarcinoma3.1
DorsalRootGanglion2.35
FetalThyroid4
Fetalbrain3.15
Fetalliver3.2
Fetallung2.65
GlobusPallidus2.25
Heart3.9
Hypothalamus3.45
Kidney2.65
Leukemia_chronicMyelogenousK-5622.85
Leukemia_promyelocytic-HL-602.75
Leukemialymphoblastic(MOLT-4)2.55
Liver4.1
Lung3.5
Lymphnode2.7
Lymphoma_burkitts(Daudi)3.95
Lymphoma_burkitts(Raji)4.3
MedullaOblongata2.85
OccipitalLobe2.8
OlfactoryBulb3.3
Ovary2.6
Pancreas2.5
PancreaticIslet3.35
ParietalLobe3.25
Pituitary4
Placenta3.25
Pons3
PrefrontalCortex3.95
Prostate3.7
Salivarygland2.5
SkeletalMuscle3.85
Skin2.5
SmoothMuscle3.6
Spinalcord3.35
SubthalamicNucleus2.8
SuperiorCervicalGanglion5.7
TemporalLobe2.8
Testis2.7
TestisGermCell2.65
TestisIntersitial2.6
TestisLeydigCell3.1
TestisSeminiferousTubule2.7
Thalamus3.15
Thymus2.5
Thyroid4
Tongue3.9
Tonsil3.05
Trachea2.6
TrigeminalGanglion3.05
Uterus2.6
UterusCorpus3.4
WholeBlood3.45
Wholebrain2.75
colon3.15
pineal_day3.92
pineal_night3.76
retina3.775
small_intestine3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P119040
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.44 ± 0.76
Basal Forebrain4.95 ± 0.13
Basal Part of Pons3.43 ± 0.58
Cerebellar Cortex4.06 ± 0.55
Cerebellar Nuclei5.02 ± 0.43
Claustrum4.09 ± 0.55
Epithalamus5 ± 0.67
Frontal Lobe3.82 ± 0.81
Globus Pallidus5.97 ± 0.56
Hypothalamus4.96 ± 0.45
Insula4 ± 0.73
Limbic Lobe4.5 ± 0.87
Mesencephalon4.85 ± 0.67
Myelencephalon4.54 ± 0.71
Occipital Lobe5.05 ± 0.45
Parietal Lobe4.38 ± 0.84
Pontine Tegmentum4.69 ± 0.76
Striatum5.46 ± 0.52
Subthalamus3.71 ± 0.34
Temporal Lobe4.58 ± 0.66
Thalamus3.98 ± 0.8
White Matter5.3 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AK220484CBCerebellum10.11
10.76
AK220484CTXCerebral cortex15.78
12.13
AK220484HIPHippocampal region9.71
8.9
AK220484HPFHippocampal formation9.49
7.98
AK220484HYHypothalamus5.23
3.38
AK220484LSXLateral septal complex8
5.66
AK220484MBMidbrain4.63
4.25
AK220484MYMedulla17.43
17.97
AK220484OLFOlfactory bulb15.89
12.83
AK220484PPons9.55
8.83
AK220484PALPallidum5.15
3.74
AK220484RHPRetrohippocampal region8.7
6.32
AK220484sAMYStriatum-like amygdalar nuclei6.53
4.53
AK220484STRStriatum3.86
2.77
AK220484STRdStriatum dorsal region2.5
1.97
AK220484STRvStriatum ventral region4.5
2.74
AK220484THThalamus4.66
3.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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