AutismKB 2.0

Annotation Detail for PCNXL2


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Basic Information Top
Gene Symbol:PCNXL2 ( FLJ11383,KIAA0435 )
Gene Full Name: pecanex-like 2 (Drosophila)
Band: 1q42.2
Quick LinksEntrez ID:80003; OMIM: NA; Uniprot ID:PCX2_HUMAN; ENSEMBL ID: ENSG00000135749; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor12 / 13630288
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor9 / 10312787
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal106 / 336030731
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain64 / 110098958
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine14 / 23447259
kidney2 / 2117779
larynx1 / 2414541
liver0 / 2077430 
lung16 / 33697447
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth9 / 67052134
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen6 / 53952111
stomach4 / 9661941
testis7 / 33044221
thymus3 / 8113136
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205689_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.7
Adipocyte3.7
AdrenalCortex3.9
Adrenalgland3.15
Amygdala4.05
Appendix3.75
AtrioventricularNode2.85
BDCA4+_DentriticCells4.25
Bonemarrow3.7
BronchialEpithelialCells3.75
CD105+_Endothelial3.85
CD14+_Monocytes4
CD19+_BCells(neg._sel.)4
CD33+_Myeloid4.9
CD34+4.75
CD4+_Tcells6.35
CD56+_NKCells4.5
CD71+_EarlyErythroid3.55
CD8+_Tcells13.6
CardiacMyocytes4.7
Caudatenucleus3.4
Cerebellum3.05
CerebellumPeduncles4.25
CiliaryGanglion2.6
CingulateCortex5.1
Colorectaladenocarcinoma3.75
DorsalRootGanglion2.85
FetalThyroid3.65
Fetalbrain3.85
Fetalliver3.2
Fetallung3.05
GlobusPallidus2.8
Heart4.75
Hypothalamus4.2
Kidney3
Leukemia_chronicMyelogenousK-5623.4
Leukemia_promyelocytic-HL-603.3
Leukemialymphoblastic(MOLT-4)3.05
Liver4.95
Lung4.1
Lymphnode3.3
Lymphoma_burkitts(Daudi)4.8
Lymphoma_burkitts(Raji)5.25
MedullaOblongata3.5
OccipitalLobe3.45
OlfactoryBulb2.95
Ovary2.45
Pancreas3.05
PancreaticIslet4.05
ParietalLobe3.95
Pituitary4.45
Placenta3.8
Pons3.6
PrefrontalCortex5.05
Prostate4.5
Salivarygland3
SkeletalMuscle4.3
Skin2.85
SmoothMuscle4.25
Spinalcord4
SubthalamicNucleus3.45
SuperiorCervicalGanglion4.2
TemporalLobe3.45
Testis3.2
TestisGermCell3.15
TestisIntersitial3.15
TestisLeydigCell3.75
TestisSeminiferousTubule3.25
Thalamus3.85
Thymus2.9
Thyroid4.75
Tongue3.65
Tonsil3.7
Trachea3.2
TrigeminalGanglion3.65
Uterus3.1
UterusCorpus3.35
WholeBlood4.05
Wholebrain3.3
colon3.8
pineal_day5.38
pineal_night4.64
retina4.575
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P225189
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.91 ± 0.47
Basal Forebrain7.37 ± 0.22
Basal Part of Pons7.42 ± 0.24
Cerebellar Cortex7.17 ± 0.31
Cerebellar Nuclei7.01 ± 0.32
Claustrum7.67 ± 0.57
Epithalamus6.52 ± 0.51
Frontal Lobe7.31 ± 0.47
Globus Pallidus7.41 ± 0.52
Hypothalamus6.9 ± 0.37
Insula7.24 ± 0.36
Limbic Lobe7.7 ± 0.38
Mesencephalon7.38 ± 0.48
Myelencephalon7.29 ± 0.42
Occipital Lobe7.49 ± 0.39
Parietal Lobe7.58 ± 0.5
Pontine Tegmentum7.33 ± 0.49
Striatum7.26 ± 0.44
Subthalamus7.39 ± 0.35
Temporal Lobe7.39 ± 0.39
Thalamus7.28 ± 0.3
White Matter6.58 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
E330039K12RikCBCerebellum12
12.33
E330039K12RikCTXCerebral cortex68.26
55.75
E330039K12RikHIPHippocampal region29.39
44.57
E330039K12RikHPFHippocampal formation37.54
43.56
E330039K12RikHYHypothalamus8.02
6.09
E330039K12RikLSXLateral septal complex4.41
3.39
E330039K12RikMBMidbrain13.55
12.53
E330039K12RikMYMedulla28.06
30.79
E330039K12RikOLFOlfactory bulb40.73
33.9
E330039K12RikPPons21.45
23.17
E330039K12RikPALPallidum9.12
8.13
E330039K12RikRHPRetrohippocampal region55.98
45.91
E330039K12RiksAMYStriatum-like amygdalar nuclei11.53
7.48
E330039K12RikSTRStriatum16.11
10.73
E330039K12RikSTRdStriatum dorsal region15.53
10.07
E330039K12RikSTRvStriatum ventral region23.68
15.08
E330039K12RikTHThalamus22.89
21.1
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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