AutismKB 2.0

Annotation Detail for PIF1


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Basic Information Top
Gene Symbol:PIF1 ( C15orf20,PIF )
Gene Full Name: PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
Band: 15q22.31
Quick LinksEntrez ID:80119; OMIM: 610953; Uniprot ID:PIF1_HUMAN; ENSEMBL ID: ENSG00000140451; HGNC ID: 26220
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus10 / 56401217
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult11 / 19391215
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal34 / 336030710
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph2 / 4427045
lymph node5 / 9161054
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P416468
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.85 ± 0.75
Basal Forebrain3.7 ± 0.65
Basal Part of Pons4.17 ± 0.41
Cerebellar Cortex3.05 ± 0.49
Cerebellar Nuclei4.26 ± 0.48
Claustrum4.27 ± 0.84
Epithalamus3.75 ± 0.99
Frontal Lobe4.02 ± 0.87
Globus Pallidus4.37 ± 0.56
Hypothalamus4.95 ± 0.8
Insula3.59 ± 0.76
Limbic Lobe3.44 ± 0.69
Mesencephalon4.4 ± 0.95
Myelencephalon4.01 ± 0.73
Occipital Lobe4.82 ± 0.7
Parietal Lobe4.35 ± 0.78
Pontine Tegmentum4.03 ± 0.8
Striatum3.9 ± 0.73
Subthalamus3.72 ± 0.17
Temporal Lobe3.58 ± 0.81
Thalamus3.65 ± 0.7
White Matter3.25 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI449441CBCerebellum2.28
2.44
AI449441CTXCerebral cortex4.97
3.07
AI449441HIPHippocampal region3.12
2.67
AI449441HPFHippocampal formation3.64
2.89
AI449441HYHypothalamus0.6
0.52
AI449441LSXLateral septal complex1.28
0.88
AI449441MBMidbrain1.73
1.47
AI449441MYMedulla8.47
8.51
AI449441OLFOlfactory bulb10.1
8.08
AI449441PPons7.15
6.64
AI449441PALPallidum2.28
1.49
AI449441RHPRetrohippocampal region5.03
3.59
AI449441sAMYStriatum-like amygdalar nuclei7.23
3.98
AI449441STRStriatum4.02
2.57
AI449441STRdStriatum dorsal region4.36
2.84
AI449441STRvStriatum ventral region3.44
2.21
AI449441THThalamus1.76
1.19
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018