AutismKB 2.0

Annotation Detail for NR4A3


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Basic Information Top
Gene Symbol:NR4A3 ( CHN,CSMF,MINOR,NOR1,TEC )
Gene Full Name: nuclear receptor subfamily 4, group A, member 3
Band: 9q22
Quick LinksEntrez ID:8013; OMIM: 600542; Uniprot ID:NR4A3_HUMAN; ENSEMBL ID: ENSG00000119508; HGNC ID: 7982
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal47 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix1 / 4817120
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver5 / 20774324
lung8 / 33697423
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach1 / 9661910
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207978_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9
Adipocyte8.25
AdrenalCortex221.75
Adrenalgland15.8
Amygdala8.15
Appendix11.5
AtrioventricularNode8.5
BDCA4+_DentriticCells8.25
Bonemarrow8.65
BronchialEpithelialCells7.7
CD105+_Endothelial8
CD14+_Monocytes8.65
CD19+_BCells(neg._sel.)8.25
CD33+_Myeloid10.2
CD34+9.4
CD4+_Tcells7.9
CD56+_NKCells8.95
CD71+_EarlyErythroid8.1
CD8+_Tcells6.95
CardiacMyocytes11.4
Caudatenucleus7.5
Cerebellum7.15
CerebellumPeduncles10.35
CiliaryGanglion7.8
CingulateCortex8.95
Colorectaladenocarcinoma8.15
DorsalRootGanglion7.45
FetalThyroid8.1
Fetalbrain8.25
Fetalliver7.3
Fetallung6.4
GlobusPallidus10.05
Heart12.75
Hypothalamus8.95
Kidney8.75
Leukemia_chronicMyelogenousK-5627.35
Leukemia_promyelocytic-HL-607.35
Leukemialymphoblastic(MOLT-4)6.7
Liver11.6
Lung9.1
Lymphnode7.15
Lymphoma_burkitts(Daudi)10.65
Lymphoma_burkitts(Raji)11.85
MedullaOblongata7.65
OccipitalLobe7.45
OlfactoryBulb6.6
Ovary7.55
Pancreas6.75
PancreaticIslet8.9
ParietalLobe10.35
Pituitary9.75
Placenta8
Pons9.1
PrefrontalCortex10.25
Prostate9.45
Salivarygland7.05
SkeletalMuscle36.5
Skin7.85
SmoothMuscle9.1
Spinalcord8.95
SubthalamicNucleus11.95
SuperiorCervicalGanglion23.7
TemporalLobe11.8
Testis7.1
TestisGermCell6.8
TestisIntersitial7
TestisLeydigCell8.35
TestisSeminiferousTubule7.2
Thalamus8.5
Thymus6.35
Thyroid9.45
Tongue11.15
Tonsil8.2
Trachea7.95
TrigeminalGanglion10.45
Uterus6.75
UterusCorpus10.85
WholeBlood8.75
Wholebrain6.9
colon8.1
pineal_day14.54
pineal_night11.66
retina10.1
small_intestine7.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P306867
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.03 ± 0.89
Basal Forebrain1.34 ± 0.31
Basal Part of Pons1.31 ± 0.41
Cerebellar Cortex1.51 ± 0.69
Cerebellar Nuclei1.74 ± 0.71
Claustrum2.18 ± 0.89
Epithalamus2.99 ± 1.56
Frontal Lobe1.49 ± 0.77
Globus Pallidus1.76 ± 0.44
Hypothalamus1.8 ± 1.02
Insula1.44 ± 0.53
Limbic Lobe1.85 ± 0.63
Mesencephalon1.73 ± 0.72
Myelencephalon1.66 ± 0.7
Occipital Lobe1.7 ± 0.77
Parietal Lobe1.57 ± 0.66
Pontine Tegmentum1.63 ± 0.74
Striatum2.1 ± 1.01
Subthalamus1.6 ± 0.54
Temporal Lobe1.44 ± 0.67
Thalamus1.38 ± 0.61
White Matter1.93 ± 0.17
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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