AutismKB 2.0

Annotation Detail for DBF4B


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Basic Information Top
Gene Symbol:DBF4B ( ASKL1,CHIFB,DRF1,FLJ13087,MGC15009,ZDBF1B )
Gene Full Name: DBF4 homolog B (S. cerevisiae)
Band: 17q21.31
Quick LinksEntrez ID:80174; OMIM: 611661; Uniprot ID:DBF4B_HUMAN; ENSEMBL ID: ENSG00000161692; HGNC ID: 17883
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst5 / 6231980
fetus5 / 5640128
neonate2 / 3109764
infant0 / 236200 
juvenile1 / 5555617
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia8 / 9584283
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal46 / 336030713
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone1 / 7165513
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye4 / 21105418
heart2 / 8962622
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph1 / 4427022
lymph node5 / 9161054
mammary gland3 / 15327119
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis14 / 33044242
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9807_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.73 ± 0.61
Basal Forebrain5.71 ± 0.44
Basal Part of Pons5.3 ± 0.56
Cerebellar Cortex5.13 ± 0.34
Cerebellar Nuclei5.72 ± 0.53
Claustrum5.73 ± 0.6
Epithalamus5.32 ± 0.38
Frontal Lobe5.13 ± 0.48
Globus Pallidus6.41 ± 0.39
Hypothalamus5.3 ± 0.36
Insula5 ± 0.39
Limbic Lobe5.34 ± 0.58
Mesencephalon5.49 ± 0.48
Myelencephalon5.34 ± 0.56
Occipital Lobe5.53 ± 0.3
Parietal Lobe5.41 ± 0.52
Pontine Tegmentum5.35 ± 0.58
Striatum5.66 ± 0.38
Subthalamus5.21 ± 0.36
Temporal Lobe5.35 ± 0.4
Thalamus5.12 ± 0.48
White Matter6.98 ± 0.4
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018