AutismKB 2.0

Annotation Detail for C16orf59


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:C16orf59 ( FLJ13909 )
Gene Full Name: chromosome 16 open reading frame 59
Band: 16p13.3
Quick LinksEntrez ID:80178; OMIM: NA; Uniprot ID:CP059_HUMAN; ENSEMBL ID: ENSG00000162062; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst6 / 6231996
fetus14 / 56401224
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor10 / 10312796
lymphoma11 / 71755153
non-neoplasia0 / 972500 
normal52 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer1 / 1026809
retinoblastoma5 / 46356107
skin tumor7 / 12494956
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood8 / 12347864
bone1 / 7165513
bone marrow1 / 4880120
brain22 / 110098919
cervix3 / 4817162
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye10 / 21105447
heart1 / 8962611
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver3 / 20774314
lung13 / 33697438
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin7 / 21057433
spleen1 / 5395218
stomach2 / 9661920
testis11 / 33044233
thymus7 / 8113186
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219556_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.2
Adipocyte3.45
AdrenalCortex3.6
Adrenalgland2.95
Amygdala3.75
Appendix3.5
AtrioventricularNode2.6
BDCA4+_DentriticCells3.9
Bonemarrow3.45
BronchialEpithelialCells3.5
CD105+_Endothelial4.15
CD14+_Monocytes3.75
CD19+_BCells(neg._sel.)3.75
CD33+_Myeloid4.55
CD34+4.5
CD4+_Tcells3.85
CD56+_NKCells4.2
CD71+_EarlyErythroid5.5
CD8+_Tcells3.4
CardiacMyocytes4.55
Caudatenucleus3.15
Cerebellum2.8
CerebellumPeduncles3.95
CiliaryGanglion2.4
CingulateCortex3.6
Colorectaladenocarcinoma3.55
DorsalRootGanglion2.6
FetalThyroid3.4
Fetalbrain3.5
Fetalliver3.2
Fetallung2.95
GlobusPallidus2.5
Heart4.35
Hypothalamus3.85
Kidney2.85
Leukemia_chronicMyelogenousK-5623.2
Leukemia_promyelocytic-HL-603.1
Leukemialymphoblastic(MOLT-4)2.9
Liver4.65
Lung3.9
Lymphnode3.05
Lymphoma_burkitts(Daudi)4.45
Lymphoma_burkitts(Raji)4.95
MedullaOblongata3.25
OccipitalLobe3.2
OlfactoryBulb2.75
Ovary2.3
Pancreas2.8
PancreaticIslet3.7
ParietalLobe3.75
Pituitary4.15
Placenta3.7
Pons3.3
PrefrontalCortex4.4
Prostate4.2
Salivarygland2.8
SkeletalMuscle3.95
Skin2.6
SmoothMuscle4
Spinalcord3.75
SubthalamicNucleus3.15
SuperiorCervicalGanglion3.9
TemporalLobe3.2
Testis3.05
TestisGermCell2.95
TestisIntersitial2.95
TestisLeydigCell3.45
TestisSeminiferousTubule3.05
Thalamus3.55
Thymus2.8
Thyroid4.4
Tongue3.45
Tonsil3.4
Trachea2.95
TrigeminalGanglion3.5
Uterus2.9
UterusCorpus3.05
WholeBlood3.85
Wholebrain3.05
colon3.5
pineal_day4.4
pineal_night4.28
retina4.25
small_intestine3.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5390_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.44 ± 0.62
Basal Forebrain5.27 ± 0.31
Basal Part of Pons5.02 ± 0.6
Cerebellar Cortex5.58 ± 0.31
Cerebellar Nuclei4.91 ± 0.6
Claustrum5.72 ± 0.71
Epithalamus4.77 ± 0.61
Frontal Lobe4.95 ± 0.52
Globus Pallidus5.36 ± 0.64
Hypothalamus4.66 ± 0.64
Insula4.9 ± 0.43
Limbic Lobe5.13 ± 0.7
Mesencephalon5.27 ± 0.57
Myelencephalon5.12 ± 0.66
Occipital Lobe5.33 ± 0.65
Parietal Lobe5.02 ± 0.57
Pontine Tegmentum4.99 ± 0.58
Striatum5.15 ± 0.69
Subthalamus5.4 ± 0.87
Temporal Lobe4.98 ± 0.66
Thalamus5.11 ± 0.47
White Matter6.33 ± 0.29
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved