AutismKB 2.0

Annotation Detail for FBXO11


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Basic Information Top
Gene Symbol:FBXO11 ( FBX11,FLJ12673,MGC44383,PRMT9,UBR6,VIT1 )
Gene Full Name: F-box protein 11
Band: 2p16.3
Quick LinksEntrez ID:80204; OMIM: 607871; Uniprot ID:FBX11_HUMAN; ENSEMBL ID: ENSG00000138081; HGNC ID: 13590
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus42 / 56401274
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor22 / 26384583
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal165 / 336030749
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone3 / 7165541
bone marrow2 / 4880140
brain62 / 110098956
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye10 / 21105447
heart4 / 8962644
intestine5 / 23447221
kidney10 / 21177747
larynx0 / 241450 
liver5 / 20774324
lung17 / 33697450
lymph1 / 4427022
lymph node11 / 91610120
mammary gland1 / 1532716
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas11 / 21481251
parathyroid6 / 20539292
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach1 / 9661910
testis23 / 33044269
thymus3 / 8113136
thyroid5 / 47473105
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203255_at
Cell line Expression level Expression bar
721_B_lymphoblasts35.75
Adipocyte8.45
AdrenalCortex27.65
Adrenalgland7.8
Amygdala12.5
Appendix9.2
AtrioventricularNode7.7
BDCA4+_DentriticCells20.75
Bonemarrow9.05
BronchialEpithelialCells10.5
CD105+_Endothelial88.55
CD14+_Monocytes35.25
CD19+_BCells(neg._sel.)12.85
CD33+_Myeloid24.75
CD34+139.1
CD4+_Tcells51.8
CD56+_NKCells11.45
CD71+_EarlyErythroid8.5
CD8+_Tcells61.05
CardiacMyocytes12.05
Caudatenucleus7.6
Cerebellum7.05
CerebellumPeduncles10.4
CiliaryGanglion6.7
CingulateCortex10.25
Colorectaladenocarcinoma11.65
DorsalRootGanglion7.05
FetalThyroid19
Fetalbrain20.85
Fetalliver11.5
Fetallung14.7
GlobusPallidus6.8
Heart11.65
Hypothalamus9.3
Kidney7.35
Leukemia_chronicMyelogenousK-5628.8
Leukemia_promyelocytic-HL-6052.75
Leukemialymphoblastic(MOLT-4)58.7
Liver12.05
Lung9.4
Lymphnode7.5
Lymphoma_burkitts(Daudi)74.45
Lymphoma_burkitts(Raji)13.45
MedullaOblongata7.8
OccipitalLobe8.4
OlfactoryBulb6.8
Ovary6.05
Pancreas7.25
PancreaticIslet9.45
ParietalLobe9.7
Pituitary16.85
Placenta11.05
Pons8.55
PrefrontalCortex63.45
Prostate19.65
Salivarygland7.3
SkeletalMuscle10.3
Skin7.15
SmoothMuscle13
Spinalcord9.7
SubthalamicNucleus8
SuperiorCervicalGanglion10.5
TemporalLobe8.2
Testis7.5
TestisGermCell10.15
TestisIntersitial9.85
TestisLeydigCell9.85
TestisSeminiferousTubule12.05
Thalamus8.95
Thymus7.2
Thyroid13.3
Tongue9.15
Tonsil17.75
Trachea7.1
TrigeminalGanglion9.1
Uterus33.5
UterusCorpus8.2
WholeBlood18.75
Wholebrain7.4
colon13.8
pineal_day15.08
pineal_night11.9
retina10.45
small_intestine9.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P357536
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.19 ± 0.25
Basal Forebrain8.26 ± 0.09
Basal Part of Pons8.44 ± 0.17
Cerebellar Cortex8.56 ± 0.14
Cerebellar Nuclei8.11 ± 0.25
Claustrum8.22 ± 0.4
Epithalamus8.61 ± 0.2
Frontal Lobe8.32 ± 0.24
Globus Pallidus8.01 ± 0.22
Hypothalamus8.37 ± 0.2
Insula8.4 ± 0.21
Limbic Lobe8.23 ± 0.34
Mesencephalon8.22 ± 0.32
Myelencephalon8.24 ± 0.33
Occipital Lobe8.1 ± 0.34
Parietal Lobe8.32 ± 0.3
Pontine Tegmentum8.2 ± 0.29
Striatum7.89 ± 0.27
Subthalamus8.23 ± 0.24
Temporal Lobe8.41 ± 0.23
Thalamus8.13 ± 0.28
White Matter8.57 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbxo11CBCerebellum10.4
10.49
Fbxo11CTXCerebral cortex30.34
21.98
Fbxo11HIPHippocampal region32.95
41.67
Fbxo11HPFHippocampal formation29.4
31.68
Fbxo11HYHypothalamus6.38
4.83
Fbxo11LSXLateral septal complex9.61
7.05
Fbxo11MBMidbrain13.47
11.55
Fbxo11MYMedulla17.66
17.52
Fbxo11OLFOlfactory bulb19.72
14.44
Fbxo11PPons11.84
11.71
Fbxo11PALPallidum7.69
6.3
Fbxo11RHPRetrohippocampal region23.89
19.22
Fbxo11sAMYStriatum-like amygdalar nuclei6.11
4.34
Fbxo11STRStriatum11.51
7.67
Fbxo11STRdStriatum dorsal region13.31
9
Fbxo11STRvStriatum ventral region9.27
5.53
Fbxo11THThalamus10.69
9.09
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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