Annotation Detail for NUP214
Basic Information Top
| Gene Symbol: | NUP214 ( CAIN,CAN,D9S46E,MGC104525,N214 ) |
|---|---|
| Gene Full Name: | nucleoporin 214kDa |
| Band: | 9q34.13 |
| Quick Links | Entrez ID:8021; OMIM: 114350; Uniprot ID:NU214_HUMAN; ENSEMBL ID: ENSG00000126883; HGNC ID: 8064 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.654530
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 8 / 62319 | 128 | |
| fetus | 40 / 564012 | 70 | |
| neonate | 2 / 31097 | 64 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 207 / 1939121 | 106 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 14 / 94178 | 148 | |
| cervical tumor | 1 / 34366 | 29 |  |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 12 / 114246 | 105 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 20 / 263845 | 75 | |
| glioma | 12 / 106883 | 112 | |
| head and neck tumor | 8 / 136302 | 58 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 284 / 3360307 | 84 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 10 / 102680 | 97 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 2 / 29757 | 67 | |
| blood | 4 / 123478 | 32 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 52 / 1100989 | 47 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 16 / 215722 | 74 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 19 / 211054 | 90 | |
| heart | 1 / 89626 | 11 | |
| intestine | 20 / 234472 | 85 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 0 / 24145 | 0 | |
| liver | 18 / 207743 | 86 | |
| lung | 23 / 336974 | 68 | |
| lymph | 4 / 44270 | 90 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 22 / 153271 | 143 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 9 / 107715 | 83 | |
| nerve | 4 / 15768 | 253 |  |
| ovary | 6 / 102051 | 58 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 8 / 41328 | 193 | |
| pituitary gland | 3 / 16585 | 180 | |
| placenta | 16 / 280825 | 56 | |
| prostate | 63 / 189345 | 332 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 8 / 210574 | 37 | |
| spleen | 4 / 53952 | 74 | |
| stomach | 8 / 96619 | 82 | |
| testis | 97 / 330442 | 293 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 8 / 232878 | 34 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 202155_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 13.15 | |
| Adipocyte | 2.6 | |
| AdrenalCortex | 3.05 | |
| Adrenalgland | 2.45 | |
| Amygdala | 3.35 | |
| Appendix | 2.9 | |
| AtrioventricularNode | 2.15 | |
| BDCA4+_DentriticCells | 33.35 | |
| Bonemarrow | 13.15 | |
| BronchialEpithelialCells | 3.2 | |
| CD105+_Endothelial | 11.4 | |
| CD14+_Monocytes | 350.95 | |
| CD19+_BCells(neg._sel.) | 6.5 | |
| CD33+_Myeloid | 224.05 | |
| CD34+ | 32.45 | |
| CD4+_Tcells | 7.55 | |
| CD56+_NKCells | 18.45 | |
| CD71+_EarlyErythroid | 3.95 | |
| CD8+_Tcells | 15 | |
| CardiacMyocytes | 3.75 | |
| Caudatenucleus | 2.7 | |
| Cerebellum | 2.5 | |
| CerebellumPeduncles | 2.55 | |
| CiliaryGanglion | 2.1 | |
| CingulateCortex | 2.95 | |
| Colorectaladenocarcinoma | 8.6 | |
| DorsalRootGanglion | 2.2 | |
| FetalThyroid | 3 | |
| Fetalbrain | 3.1 | |
| Fetalliver | 2.65 | |
| Fetallung | 2.6 | |
| GlobusPallidus | 2.2 | |
| Heart | 9.25 | |
| Hypothalamus | 3.4 | |
| Kidney | 2 | |
| Leukemia_chronicMyelogenousK-562 | 60.65 | |
| Leukemia_promyelocytic-HL-60 | 2.55 | |
| Leukemialymphoblastic(MOLT-4) | 3.15 | |
| Liver | 3.95 | |
| Lung | 3.9 | |
| Lymphnode | 2.6 | |
| Lymphoma_burkitts(Daudi) | 3.9 | |
| Lymphoma_burkitts(Raji) | 3.65 | |
| MedullaOblongata | 2.8 | |
| OccipitalLobe | 2.75 | |
| OlfactoryBulb | 2.5 | |
| Ovary | 2 | |
| Pancreas | 2.4 | |
| PancreaticIslet | 3.3 | |
| ParietalLobe | 2.9 | |
| Pituitary | 3.55 | |
| Placenta | 4.25 | |
| Pons | 2.8 | |
| PrefrontalCortex | 4.8 | |
| Prostate | 4.6 | |
| Salivarygland | 2.45 | |
| SkeletalMuscle | 2.95 | |
| Skin | 2.35 | |
| SmoothMuscle | 3.3 | |
| Spinalcord | 3.3 | |
| SubthalamicNucleus | 2.6 | |
| SuperiorCervicalGanglion | 2.9 | |
| TemporalLobe | 2.7 | |
| Testis | 72.1 | |
| TestisGermCell | 83.85 | |
| TestisIntersitial | 143 | |
| TestisLeydigCell | 68.8 | |
| TestisSeminiferousTubule | 69.45 | |
| Thalamus | 3.15 | |
| Thymus | 27.95 | |
| Thyroid | 4.05 | |
| Tongue | 2.95 | |
| Tonsil | 3 | |
| Trachea | 2.4 | |
| TrigeminalGanglion | 2.95 | |
| Uterus | 3.25 | |
| UterusCorpus | 2.7 | |
| WholeBlood | 180.6 | |
| Wholebrain | 2.7 | |
| colon | 3.1 | |
| pineal_day | 6.32 | |
| pineal_night | 6.24 | |
| retina | 7.725 | |
| small_intestine | 3 | |
- Probe name: CUST_12378_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.83 ± 0.43 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.99 ± 0.18 | |
| Basal Part of Pons | 4.85 ± 0.32 | |
| Cerebellar Cortex | 5.13 ± 0.4 | |
| Cerebellar Nuclei | 4.9 ± 0.55 | |
| Claustrum | 4.71 ± 0.85 | |
| Epithalamus | 4.77 ± 0.57 | |
| Frontal Lobe | 4.96 ± 0.38 | |
| Globus Pallidus | 4.84 ± 0.35 | |
| Hypothalamus | 4.69 ± 0.15 | |
| Insula | 4.85 ± 0.4 | |
| Limbic Lobe | 4.87 ± 0.42 | |
| Mesencephalon | 4.87 ± 0.5 | |
| Myelencephalon | 4.88 ± 0.48 | |
| Occipital Lobe | 4.97 ± 0.44 | |
| Parietal Lobe | 4.89 ± 0.42 | |
| Pontine Tegmentum | 4.98 ± 0.36 | |
| Striatum | 5.01 ± 0.36 | |
| Subthalamus | 5 ± 0.33 | |
| Temporal Lobe | 4.93 ± 0.36 | |
| Thalamus | 5.02 ± 0.5 | |
| White Matter | 6.15 ± 0.19 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nup214 | CB | Cerebellum | 32.07 | |
| 34.51 | | |||
| Nup214 | CTX | Cerebral cortex | 38.16 | |
| 25.57 | | |||
| Nup214 | HIP | Hippocampal region | 29.61 | |
| 34.55 | | |||
| Nup214 | HPF | Hippocampal formation | 30.74 | |
| 29.8 | | |||
| Nup214 | HY | Hypothalamus | 13.45 | |
| 10.38 | | |||
| Nup214 | LSX | Lateral septal complex | 12.55 | |
| 8.12 | | |||
| Nup214 | MB | Midbrain | 20.69 | |
| 17.08 | | |||
| Nup214 | MY | Medulla | 26.69 | |
| 24.9 | | |||
| Nup214 | OLF | Olfactory bulb | 42.94 | |
| 34.01 | | |||
| Nup214 | P | Pons | 24.07 | |
| 22.3 | | |||
| Nup214 | PAL | Pallidum | 17.63 | |
| 14.2 | | |||
| Nup214 | RHP | Retrohippocampal region | 32.77 | |
| 23.67 | | |||
| Nup214 | sAMY | Striatum-like amygdalar nuclei | 18.12 | |
| 11.94 | | |||
| Nup214 | STR | Striatum | 23.65 | |
| 16.61 | | |||
| Nup214 | STRd | Striatum dorsal region | 22.11 | |
| 15.99 | | |||
| Nup214 | STRv | Striatum ventral region | 33.81 | |
| 21.88 | | |||
| Nup214 | TH | Thalamus | 29.28 | |
| 22.72 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00007950 | 14 | 1001 | 1014 | TSCKDDEAVVQAPR | Peptide Atlas |