AutismKB 2.0

Annotation Detail for LHX3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LHX3 ( CPHD3,DKFZp762A2013,LIM3,M2-LHX3 )
Gene Full Name: LIM homeobox 3
Band: 9q34.3
Quick LinksEntrez ID:8022; OMIM: 600577; Uniprot ID:LHX3_HUMAN; ENSEMBL ID: ENSG00000107187; HGNC ID: 6595
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal5 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma6 / 46356129
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye9 / 21105442
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221670_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.85
Adipocyte14.4
AdrenalCortex13.15
Adrenalgland12.1
Amygdala16
Appendix12.55
AtrioventricularNode16.45
BDCA4+_DentriticCells4.4
Bonemarrow23.55
BronchialEpithelialCells8.9
CD105+_Endothelial7.5
CD14+_Monocytes7.3
CD19+_BCells(neg._sel.)8.85
CD33+_Myeloid11.3
CD34+6.6
CD4+_Tcells6.8
CD56+_NKCells5.15
CD71+_EarlyErythroid6.8
CD8+_Tcells5
CardiacMyocytes13.35
Caudatenucleus12.1
Cerebellum11.25
CerebellumPeduncles14.1
CiliaryGanglion7.4
CingulateCortex14.8
Colorectaladenocarcinoma12.4
DorsalRootGanglion10.3
FetalThyroid14.2
Fetalbrain12.2
Fetalliver10.8
Fetallung15.35
GlobusPallidus9.15
Heart22.65
Hypothalamus13.75
Kidney10.05
Leukemia_chronicMyelogenousK-56212.2
Leukemia_promyelocytic-HL-6010.3
Leukemialymphoblastic(MOLT-4)10.1
Liver16.5
Lung14.95
Lymphnode10.8
Lymphoma_burkitts(Daudi)19.1
Lymphoma_burkitts(Raji)17.35
MedullaOblongata11.3
OccipitalLobe11.35
OlfactoryBulb12.1
Ovary8.15
Pancreas10.05
PancreaticIslet13.35
ParietalLobe14.6
Pituitary109.25
Placenta17.25
Pons11.75
PrefrontalCortex14.65
Prostate16.3
Salivarygland11.55
SkeletalMuscle20.05
Skin9.55
SmoothMuscle10.2
Spinalcord19.15
SubthalamicNucleus14.2
SuperiorCervicalGanglion14.15
TemporalLobe11.35
Testis14.7
TestisGermCell10.05
TestisIntersitial9.85
TestisLeydigCell10.8
TestisSeminiferousTubule17.5
Thalamus12.65
Thymus10.2
Thyroid16.05
Tongue20.75
Tonsil12
Trachea14.35
TrigeminalGanglion13.65
Uterus10.95
UterusCorpus18.45
WholeBlood13.5
Wholebrain11.25
colon11.05
pineal_day672.4
pineal_night678.26
retina11.1
small_intestine8.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16782_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.5 ± 1.02
Basal Forebrain2.06 ± 0.2
Basal Part of Pons1.87 ± 0.47
Cerebellar Cortex1.93 ± 0.77
Cerebellar Nuclei2.41 ± 0.65
Claustrum3.05 ± 0.91
Epithalamus1.79 ± 0.8
Frontal Lobe1.91 ± 0.62
Globus Pallidus2.7 ± 0.3
Hypothalamus2.14 ± 0.62
Insula2.12 ± 1.01
Limbic Lobe2.16 ± 0.73
Mesencephalon2.23 ± 0.69
Myelencephalon2.15 ± 0.71
Occipital Lobe2.29 ± 0.82
Parietal Lobe2.19 ± 0.79
Pontine Tegmentum2.16 ± 0.73
Striatum2.23 ± 0.46
Subthalamus2.29 ± 0.72
Temporal Lobe2.06 ± 0.73
Thalamus2.08 ± 0.62
White Matter2.52 ± 0.19
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved