AutismKB 2.0

Annotation Detail for ACSF2


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Basic Information Top
Gene Symbol:ACSF2 ( ACSMW,AVYV493,FLJ20920 )
Gene Full Name: acyl-CoA synthetase family member 2
Band: 17q21.33
Quick LinksEntrez ID:80221; OMIM: 610465; Uniprot ID:ACSF2_HUMAN; ENSEMBL ID: ENSG00000167107; HGNC ID: 26101
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor6 / 26384522
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor11 / 68959159
leukemia9 / 9584293
liver tumor9 / 9635993
lung tumor4 / 10312738
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal138 / 336030741
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites2 / 4001549
bladder7 / 29757235
blood6 / 12347848
bone3 / 7165541
bone marrow1 / 4880120
brain29 / 110098926
cervix5 / 48171103
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye4 / 21105418
heart10 / 89626111
intestine13 / 23447255
kidney25 / 211777118
larynx0 / 241450 
liver12 / 20774357
lung12 / 33697435
lymph0 / 442700 
lymph node5 / 9161054
mammary gland3 / 15327119
mouth2 / 6705229
muscle3 / 10771527
nerve0 / 157680 
ovary3 / 10205129
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta15 / 28082553
prostate4 / 18934521
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach1 / 9661910
testis7 / 33044221
thymus7 / 8113186
thyroid7 / 47473147
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218844_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.45
Adipocyte17.6
AdrenalCortex12.75
Adrenalgland17.2
Amygdala7
Appendix6.95
AtrioventricularNode5.05
BDCA4+_DentriticCells7.7
Bonemarrow6.55
BronchialEpithelialCells6.65
CD105+_Endothelial6.75
CD14+_Monocytes7.15
CD19+_BCells(neg._sel.)7.25
CD33+_Myeloid8.6
CD34+8.65
CD4+_Tcells7.35
CD56+_NKCells8.1
CD71+_EarlyErythroid6.25
CD8+_Tcells6.55
CardiacMyocytes8.3
Caudatenucleus6
Cerebellum5.4
CerebellumPeduncles7.7
CiliaryGanglion4.95
CingulateCortex6.8
Colorectaladenocarcinoma6.5
DorsalRootGanglion5.15
FetalThyroid7.1
Fetalbrain6.65
Fetalliver5.75
Fetallung5.65
GlobusPallidus5.05
Heart9.95
Hypothalamus7.35
Kidney100.8
Leukemia_chronicMyelogenousK-5626.05
Leukemia_promyelocytic-HL-605.85
Leukemialymphoblastic(MOLT-4)5.8
Liver14.6
Lung7.45
Lymphnode5.8
Lymphoma_burkitts(Daudi)8.55
Lymphoma_burkitts(Raji)11.45
MedullaOblongata6.15
OccipitalLobe6
OlfactoryBulb5.3
Ovary4.45
Pancreas5.3
PancreaticIslet7.15
ParietalLobe7.05
Pituitary7.75
Placenta7.05
Pons6.35
PrefrontalCortex8.35
Prostate7.6
Salivarygland5.3
SkeletalMuscle8.4
Skin5.1
SmoothMuscle7.4
Spinalcord7.65
SubthalamicNucleus6.15
SuperiorCervicalGanglion8.6
TemporalLobe7.8
Testis5.7
TestisGermCell5.6
TestisIntersitial5.6
TestisLeydigCell6.65
TestisSeminiferousTubule5.75
Thalamus7.5
Thymus5.35
Thyroid14.25
Tongue7
Tonsil6.55
Trachea5.6
TrigeminalGanglion6.6
Uterus5.25
UterusCorpus5.9
WholeBlood7.15
Wholebrain5.65
colon14.2
pineal_day8.2
pineal_night8.1
retina8.35
small_intestine9.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6548_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.16 ± 0.66
Basal Forebrain5.5 ± 0.36
Basal Part of Pons4.75 ± 0.5
Cerebellar Cortex4.51 ± 0.31
Cerebellar Nuclei5.28 ± 0.73
Claustrum5.52 ± 0.76
Epithalamus3.9 ± 0.8
Frontal Lobe5.1 ± 0.71
Globus Pallidus5.8 ± 0.59
Hypothalamus4.39 ± 1.04
Insula4.78 ± 0.64
Limbic Lobe5.13 ± 0.68
Mesencephalon5.18 ± 0.57
Myelencephalon5.22 ± 0.77
Occipital Lobe5.17 ± 0.83
Parietal Lobe5.09 ± 0.66
Pontine Tegmentum5.11 ± 0.75
Striatum5.68 ± 0.69
Subthalamus5.3 ± 0.34
Temporal Lobe4.86 ± 0.68
Thalamus5.55 ± 0.52
White Matter5.16 ± 0.39
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005031 17 558 574 LKDGEETTVEEIKAFCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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