AutismKB 2.0

Annotation Detail for WDR26


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Basic Information Top
Gene Symbol:WDR26 ( CDW2,FLJ21016,MIP2 )
Gene Full Name: WD repeat domain 26
Band: 1q42.11-q42.12
Quick LinksEntrez ID:80232; OMIM: NA; Uniprot ID:WDR26_HUMAN; ENSEMBL ID: ENSG00000162923; HGNC ID: 21208
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst4 / 6231964
fetus70 / 564012124
neonate0 / 310970 
infant2 / 2362084
juvenile3 / 5555653
adult144 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor16 / 26384560
glioma6 / 10688356
head and neck tumor11 / 13630280
kidney tumor4 / 6895958
leukemia9 / 9584293
liver tumor3 / 9635931
lung tumor6 / 10312758
lymphoma3 / 7175541
non-neoplasia5 / 9725051
normal295 / 336030787
ovarian tumor6 / 7668278
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer8 / 10268077
retinoblastoma4 / 4635686
skin tumor15 / 124949120
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites1 / 4001524
bladder4 / 29757134
blood11 / 12347889
bone4 / 7165555
bone marrow4 / 4880181
brain69 / 110098962
cervix0 / 481710 
connective tissue6 / 14925540
ear4 / 16212246
embryonic tissue14 / 21572264
esophagus0 / 202090 
eye14 / 21105466
heart4 / 8962644
intestine17 / 23447272
kidney29 / 211777136
larynx4 / 24145165
liver9 / 20774343
lung27 / 33697480
lymph3 / 4427067
lymph node15 / 91610163
mammary gland10 / 15327165
mouth6 / 6705289
muscle12 / 107715111
nerve3 / 15768190
ovary6 / 10205158
pancreas9 / 21481241
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta18 / 28082564
prostate11 / 18934558
salivary gland0 / 201550 
skin20 / 21057494
spleen3 / 5395255
stomach10 / 96619103
testis27 / 33044281
thymus5 / 8113161
thyroid6 / 47473126
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218107_at
Cell line Expression level Expression bar
721_B_lymphoblasts474.5
Adipocyte120.15
AdrenalCortex56.65
Adrenalgland56.9
Amygdala73.5
Appendix71.75
AtrioventricularNode6.6
BDCA4+_DentriticCells547.85
Bonemarrow195.4
BronchialEpithelialCells92.35
CD105+_Endothelial180.6
CD14+_Monocytes436.55
CD19+_BCells(neg._sel.)450.95
CD33+_Myeloid550.2
CD34+297.85
CD4+_Tcells548.8
CD56+_NKCells842.75
CD71+_EarlyErythroid1716.5
CD8+_Tcells561.35
CardiacMyocytes105.2
Caudatenucleus41.15
Cerebellum39.7
CerebellumPeduncles20.7
CiliaryGanglion10.7
CingulateCortex8.8
Colorectaladenocarcinoma44.05
DorsalRootGanglion7.65
FetalThyroid61.85
Fetalbrain39.85
Fetalliver244.1
Fetallung187
GlobusPallidus27.9
Heart9.35
Hypothalamus75.85
Kidney50.7
Leukemia_chronicMyelogenousK-562129.2
Leukemia_promyelocytic-HL-6088.2
Leukemialymphoblastic(MOLT-4)77.3
Liver12.65
Lung66.65
Lymphnode139.9
Lymphoma_burkitts(Daudi)120.75
Lymphoma_burkitts(Raji)64.6
MedullaOblongata41.4
OccipitalLobe47.1
OlfactoryBulb53
Ovary28.7
Pancreas34.7
PancreaticIslet100.75
ParietalLobe65.6
Pituitary106.4
Placenta206.05
Pons34.9
PrefrontalCortex48.4
Prostate48.7
Salivarygland65.15
SkeletalMuscle37.85
Skin43.1
SmoothMuscle188.05
Spinalcord76.4
SubthalamicNucleus40.25
SuperiorCervicalGanglion20.05
TemporalLobe36.85
Testis131.8
TestisGermCell242.95
TestisIntersitial279.35
TestisLeydigCell163.25
TestisSeminiferousTubule135.1
Thalamus42.2
Thymus110.1
Thyroid102.6
Tongue60.85
Tonsil165.6
Trachea85.65
TrigeminalGanglion12.15
Uterus57.55
UterusCorpus53.05
WholeBlood537.7
Wholebrain39.25
colon55.3
pineal_day238.04
pineal_night198.74
retina96.2
small_intestine45.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P85604
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.22 ± 0.19
Basal Forebrain7.98 ± 0.19
Basal Part of Pons7.87 ± 0.2
Cerebellar Cortex7.85 ± 0.13
Cerebellar Nuclei7.95 ± 0.22
Claustrum8.1 ± 0.3
Epithalamus8.07 ± 0.18
Frontal Lobe8.06 ± 0.24
Globus Pallidus8.14 ± 0.18
Hypothalamus8 ± 0.27
Insula8.12 ± 0.21
Limbic Lobe8.2 ± 0.25
Mesencephalon8.04 ± 0.22
Myelencephalon8.01 ± 0.28
Occipital Lobe7.99 ± 0.28
Parietal Lobe8.01 ± 0.23
Pontine Tegmentum8.08 ± 0.28
Striatum8.31 ± 0.19
Subthalamus7.92 ± 0.05
Temporal Lobe8.09 ± 0.23
Thalamus7.89 ± 0.23
White Matter8.32 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr26CBCerebellum22.94
29.82
Wdr26CTXCerebral cortex90.13
70.04
Wdr26HIPHippocampal region59.32
98.98
Wdr26HPFHippocampal formation59.25
76.75
Wdr26HYHypothalamus27.61
21
Wdr26LSXLateral septal complex67.76
52.24
Wdr26MBMidbrain34.71
30.29
Wdr26MYMedulla20.79
20.8
Wdr26OLFOlfactory bulb64.42
55.86
Wdr26PPons25.88
25.35
Wdr26PALPallidum28.09
25.01
Wdr26RHPRetrohippocampal region58.63
49.13
Wdr26sAMYStriatum-like amygdalar nuclei37.96
28.79
Wdr26STRStriatum49.98
36.24
Wdr26STRdStriatum dorsal region52.02
37.85
Wdr26STRvStriatum ventral region47.47
32.64
Wdr26THThalamus53.7
45.74
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004805 18 323 340 LDNNLDSVSLLIDHVCSR Peptide Atlas
WDR26_HUMAN_0 0 0 0 LALLNVATQGVHLWDLQDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018