AutismKB 2.0

Annotation Detail for C16orf70


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Basic Information Top
Gene Symbol:C16orf70 ( C16orf6,FLJ12076,LIN10,lin-10 )
Gene Full Name: chromosome 16 open reading frame 70
Band: 16q22.1
Quick LinksEntrez ID:80262; OMIM: NA; Uniprot ID:CP070_HUMAN; ENSEMBL ID: ENSG00000125149; HGNC ID: 29564
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma9 / 10688384
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor10 / 10312796
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal87 / 336030725
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone7 / 7165597
bone marrow0 / 488010 
brain17 / 110098915
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye14 / 21105466
heart3 / 8962633
intestine11 / 23447246
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung19 / 33697456
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth2 / 6705229
muscle1 / 1077159
nerve2 / 15768126
ovary6 / 10205158
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland5 / 16585301
placenta6 / 28082521
prostate9 / 18934547
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P206382
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.71 ± 0.28
Basal Forebrain7.44 ± 0.08
Basal Part of Pons8.02 ± 0.15
Cerebellar Cortex7.69 ± 0.19
Cerebellar Nuclei7.76 ± 0.2
Claustrum7.88 ± 0.29
Epithalamus7.38 ± 0.14
Frontal Lobe7.84 ± 0.24
Globus Pallidus7.51 ± 0.26
Hypothalamus7.41 ± 0.23
Insula7.87 ± 0.27
Limbic Lobe8.08 ± 0.27
Mesencephalon7.67 ± 0.33
Myelencephalon7.75 ± 0.27
Occipital Lobe7.68 ± 0.27
Parietal Lobe7.74 ± 0.28
Pontine Tegmentum7.72 ± 0.31
Striatum7.36 ± 0.39
Subthalamus7.66 ± 0.06
Temporal Lobe7.93 ± 0.28
Thalamus7.6 ± 0.22
White Matter8.66 ± 0.54
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D230025D16RikCBCerebellum2.01
2.49
D230025D16RikCTXCerebral cortex4.22
3.81
D230025D16RikHIPHippocampal region7.02
6.36
D230025D16RikHPFHippocampal formation5.03
4.57
D230025D16RikHYHypothalamus0.96
0.72
D230025D16RikLSXLateral septal complex0.37
0.46
D230025D16RikMBMidbrain1.25
1.59
D230025D16RikMYMedulla0.45
0.84
D230025D16RikOLFOlfactory bulb0.81
0.57
D230025D16RikPPons0.94
1.38
D230025D16RikPALPallidum0.62
0.61
D230025D16RikRHPRetrohippocampal region1.79
2.05
D230025D16RiksAMYStriatum-like amygdalar nuclei1.72
1.13
D230025D16RikSTRStriatum3.38
4.49
D230025D16RikSTRdStriatum dorsal region5.07
7.14
D230025D16RikSTRvStriatum ventral region0.42
0.39
D230025D16RikTHThalamus2.04
1.91
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CP070_HUMAN_1 10 1 10 MLDLEVVPER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018