AutismKB 2.0

Annotation Detail for STAM


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Basic Information Top
Gene Symbol:STAM ( DKFZp686J2352,STAM1 )
Gene Full Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
Band: 10p12.33
Quick LinksEntrez ID:8027; OMIM: 601899; Uniprot ID:STAM1_HUMAN; ENSEMBL ID: ENSG00000136738; HGNC ID: 11357
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus37 / 56401265
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor3 / 17290173
gastrointestinal tumor3 / 11936925
germ cell tumor18 / 26384568
glioma8 / 10688374
head and neck tumor5 / 13630236
kidney tumor5 / 6895972
leukemia3 / 9584231
liver tumor4 / 9635941
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal143 / 336030742
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood5 / 12347840
bone3 / 7165541
bone marrow1 / 4880120
brain70 / 110098963
cervix3 / 4817162
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus3 / 20209148
eye7 / 21105433
heart1 / 8962611
intestine10 / 23447242
kidney14 / 21177766
larynx0 / 241450 
liver5 / 20774324
lung21 / 33697462
lymph1 / 4427022
lymph node4 / 9161043
mammary gland2 / 15327113
mouth2 / 6705229
muscle0 / 1077150 
nerve2 / 15768126
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate5 / 18934526
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach1 / 9661910
testis12 / 33044236
thymus9 / 81131110
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus11 / 23287847
vascular4 / 5178077
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203544_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts23.55
Adipocyte6.05
AdrenalCortex5.95
Adrenalgland5.2
Amygdala53.2
Appendix5.75
AtrioventricularNode4.4
BDCA4+_DentriticCells15.7
Bonemarrow5.7
BronchialEpithelialCells37.8
CD105+_Endothelial64.15
CD14+_Monocytes9.9
CD19+_BCells(neg._sel.)6.3
CD33+_Myeloid13.45
CD34+41.15
CD4+_Tcells14.6
CD56+_NKCells7.7
CD71+_EarlyErythroid42.3
CD8+_Tcells8.6
CardiacMyocytes8.2
Caudatenucleus5.1
Cerebellum8.5
CerebellumPeduncles7.15
CiliaryGanglion4.1
CingulateCortex6.7
Colorectaladenocarcinoma6.4
DorsalRootGanglion4.45
FetalThyroid5.1
Fetalbrain18.5
Fetalliver7.2
Fetallung11.45
GlobusPallidus4.7
Heart7.4
Hypothalamus48.5
Kidney4.45
Leukemia_chronicMyelogenousK-5625.25
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)15.05
Liver7.6
Lung6.3
Lymphnode4.9
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)8.1
MedullaOblongata6.15
OccipitalLobe23.8
OlfactoryBulb4.55
Ovary7.9
Pancreas4.2
PancreaticIslet6.1
ParietalLobe8.65
Pituitary6.5
Placenta8.25
Pons5.15
PrefrontalCortex26.35
Prostate13.95
Salivarygland4.7
SkeletalMuscle6.55
Skin4.5
SmoothMuscle7.35
Spinalcord14.55
SubthalamicNucleus5.55
SuperiorCervicalGanglion6.65
TemporalLobe5.25
Testis4.9
TestisGermCell4.8
TestisIntersitial4.6
TestisLeydigCell5.65
TestisSeminiferousTubule4.65
Thalamus6.7
Thymus5.8
Thyroid9.1
Tongue5.6
Tonsil5.2
Trachea5.15
TrigeminalGanglion5.75
Uterus10.8
UterusCorpus5
WholeBlood10
Wholebrain51.75
colon5.95
pineal_day57.42
pineal_night45.98
retina12.4
small_intestine9.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15342_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.99 ± 0.19
Basal Forebrain6.89 ± 0.09
Basal Part of Pons7.16 ± 0.26
Cerebellar Cortex7.39 ± 0.19
Cerebellar Nuclei7.24 ± 0.21
Claustrum7.32 ± 0.57
Epithalamus6.69 ± 0.42
Frontal Lobe6.98 ± 0.33
Globus Pallidus6.92 ± 0.19
Hypothalamus6.96 ± 0.37
Insula7.01 ± 0.28
Limbic Lobe6.99 ± 0.41
Mesencephalon7.07 ± 0.43
Myelencephalon6.99 ± 0.39
Occipital Lobe7.1 ± 0.27
Parietal Lobe7.09 ± 0.36
Pontine Tegmentum6.95 ± 0.31
Striatum6.52 ± 0.31
Subthalamus6.93 ± 0.64
Temporal Lobe7.02 ± 0.31
Thalamus7.08 ± 0.32
White Matter8 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
StamCBCerebellum9.1
10.42
StamCTXCerebral cortex15.28
11.64
StamHIPHippocampal region12.96
12.9
StamHPFHippocampal formation10.8
9.83
StamHYHypothalamus5.17
4.14
StamLSXLateral septal complex4.79
3.41
StamMBMidbrain6.28
6.06
StamMYMedulla10.18
11.04
StamOLFOlfactory bulb12.6
9.84
StamPPons7.17
7.88
StamPALPallidum6.36
5.91
StamRHPRetrohippocampal region7.95
6.19
StamsAMYStriatum-like amygdalar nuclei4.45
3.31
StamSTRStriatum4.29
3.32
StamSTRdStriatum dorsal region4.28
3.49
StamSTRvStriatum ventral region3.96
2.68
StamTHThalamus7.25
6.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00063299 17 233 249 AGEIITVLDDSDPNWWK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018