Annotation Detail for HSD3B7
Basic Information Top
| Gene Symbol: | HSD3B7 ( PFIC4,SDR11E3 ) |
|---|---|
| Gene Full Name: | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 |
| Band: | 16p11.2 |
| Quick Links | Entrez ID:80270; OMIM: 607764; Uniprot ID:3BHS7_HUMAN; ENSEMBL ID: ENSG00000099377; HGNC ID: 18324 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.460618
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 3 / 564012 | 5 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 29 / 1939121 | 14 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 |  |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 5 / 68959 | 72 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 38 / 3360307 | 11 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 7 / 1100989 | 6 | |
| cervix | 3 / 48171 | 62 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 1 / 89626 | 11 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 10 / 336974 | 29 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 2 / 330442 | 6 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P206819
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.41 ± 1 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.98 ± 0.26 | |
| Basal Part of Pons | 1.6 ± 0.38 | |
| Cerebellar Cortex | 1.99 ± 0.72 | |
| Cerebellar Nuclei | 2.26 ± 0.72 | |
| Claustrum | 2.85 ± 0.85 | |
| Epithalamus | 1.66 ± 0.81 | |
| Frontal Lobe | 1.88 ± 0.68 | |
| Globus Pallidus | 2.42 ± 0.45 | |
| Hypothalamus | 2.05 ± 0.61 | |
| Insula | 1.83 ± 0.54 | |
| Limbic Lobe | 1.9 ± 0.66 | |
| Mesencephalon | 2.13 ± 0.73 | |
| Myelencephalon | 2 ± 0.68 | |
| Occipital Lobe | 1.97 ± 0.61 | |
| Parietal Lobe | 2 ± 0.79 | |
| Pontine Tegmentum | 2.03 ± 0.72 | |
| Striatum | 1.93 ± 0.6 | |
| Subthalamus | 2.25 ± 0.58 | |
| Temporal Lobe | 1.9 ± 0.72 | |
| Thalamus | 1.95 ± 0.63 | |
| White Matter | 2.25 ± 0.11 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Hsd3b7 | CB | Cerebellum | 1.85 | |
| 2.19 | | |||
| Hsd3b7 | CTX | Cerebral cortex | 2.59 | |
| 2.02 | | |||
| Hsd3b7 | HIP | Hippocampal region | 6.46 | |
| 6.98 | | |||
| Hsd3b7 | HPF | Hippocampal formation | 6.07 | |
| 5.99 | | |||
| Hsd3b7 | HY | Hypothalamus | 2.79 | |
| 2.78 | | |||
| Hsd3b7 | LSX | Lateral septal complex | 1.32 | |
| 1.03 | | |||
| Hsd3b7 | MB | Midbrain | 1.33 | |
| 1.76 | | |||
| Hsd3b7 | MY | Medulla | 1.24 | |
| 2.42 | | |||
| Hsd3b7 | OLF | Olfactory bulb | 13.58 | |
| 12.62 | | |||
| Hsd3b7 | P | Pons | 3.44 | |
| 4.29 | | |||
| Hsd3b7 | PAL | Pallidum | 3.28 | |
| 2.88 | | |||
| Hsd3b7 | RHP | Retrohippocampal region | 5.4 | |
| 4.56 | | |||
| Hsd3b7 | sAMY | Striatum-like amygdalar nuclei | 5.48 | |
| 3.92 | | |||
| Hsd3b7 | STR | Striatum | 2.62 | |
| 2.05 | | |||
| Hsd3b7 | STRd | Striatum dorsal region | 0.42 | |
| 0.37 | | |||
| Hsd3b7 | STRv | Striatum ventral region | 9.83 | |
| 6.97 | | |||
| Hsd3b7 | TH | Thalamus | 2.82 | |
| 2.54 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00040526 | 19 | 145 | 163 | GNEDTPYEAVHRHPYPCSK | Peptide Atlas |