AutismKB 2.0

Annotation Detail for PDGFD


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Basic Information Top
Gene Symbol:PDGFD ( IEGF,MGC26867,SCDGF-B,SCDGFB )
Gene Full Name: platelet derived growth factor D
Band: 11q22.3
Quick LinksEntrez ID:80310; OMIM: 609673; Uniprot ID:PDGFD_HUMAN; ENSEMBL ID: ENSG00000170962; HGNC ID: 30620
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult24 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal80 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone3 / 7165541
bone marrow2 / 4880140
brain10 / 11009899
cervix0 / 481710 
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye5 / 21105423
heart2 / 8962622
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node13 / 91610141
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis23 / 33044269
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea10 / 52413190
umbilical cord0 / 136800 
uterus12 / 23287851
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219304_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.4
Adipocyte108.85
AdrenalCortex113.5
Adrenalgland59.15
Amygdala3.7
Appendix6
AtrioventricularNode3.05
BDCA4+_DentriticCells3.85
Bonemarrow3.4
BronchialEpithelialCells3.45
CD105+_Endothelial3.5
CD14+_Monocytes3.7
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid4.5
CD34+4.45
CD4+_Tcells3.8
CD56+_NKCells109.05
CD71+_EarlyErythroid3.25
CD8+_Tcells3.4
CardiacMyocytes4.7
Caudatenucleus3.15
Cerebellum2.8
CerebellumPeduncles3.95
CiliaryGanglion3.35
CingulateCortex3.55
Colorectaladenocarcinoma3.5
DorsalRootGanglion3
FetalThyroid11.35
Fetalbrain3.5
Fetalliver2.95
Fetallung2.9
GlobusPallidus4.25
Heart4.45
Hypothalamus3.8
Kidney2.8
Leukemia_chronicMyelogenousK-5623.65
Leukemia_promyelocytic-HL-603.1
Leukemialymphoblastic(MOLT-4)2.8
Liver4.6
Lung3.8
Lymphnode3.05
Lymphoma_burkitts(Daudi)5.6
Lymphoma_burkitts(Raji)4.85
MedullaOblongata3.2
OccipitalLobe3.1
OlfactoryBulb3.65
Ovary49.25
Pancreas2.85
PancreaticIslet29.6
ParietalLobe3.75
Pituitary51.95
Placenta3.6
Pons3.4
PrefrontalCortex4.4
Prostate4.15
Salivarygland2.95
SkeletalMuscle4
Skin6.8
SmoothMuscle3.95
Spinalcord4.4
SubthalamicNucleus3.2
SuperiorCervicalGanglion10.8
TemporalLobe3.2
Testis3
TestisGermCell3.8
TestisIntersitial2.95
TestisLeydigCell3.45
TestisSeminiferousTubule3
Thalamus3.55
Thymus2.8
Thyroid9
Tongue3.4
Tonsil3.4
Trachea2.9
TrigeminalGanglion3.85
Uterus5.05
UterusCorpus3.15
WholeBlood3.85
Wholebrain3.1
colon3.5
pineal_day4.38
pineal_night4.76
retina8.075
small_intestine3.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14375_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.4 ± 0.92
Basal Forebrain4.32 ± 0.4
Basal Part of Pons4.08 ± 0.61
Cerebellar Cortex3.65 ± 0.8
Cerebellar Nuclei5.97 ± 1.08
Claustrum5 ± 1.04
Epithalamus4.84 ± 1.41
Frontal Lobe3.99 ± 0.87
Globus Pallidus3.8 ± 0.98
Hypothalamus6.16 ± 0.5
Insula4.97 ± 0.82
Limbic Lobe4.24 ± 0.72
Mesencephalon4.89 ± 1.37
Myelencephalon4.69 ± 0.95
Occipital Lobe5.07 ± 0.96
Parietal Lobe5.21 ± 0.95
Pontine Tegmentum5.14 ± 1.25
Striatum4.93 ± 0.76
Subthalamus3.89 ± 0.9
Temporal Lobe5.27 ± 0.82
Thalamus3.85 ± 0.89
White Matter3.13 ± 0.88
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PdgfdCBCerebellum4.53
4.31
PdgfdCTXCerebral cortex12.43
8.08
PdgfdHIPHippocampal region12.7
9.5
PdgfdHPFHippocampal formation17.85
14.26
PdgfdHYHypothalamus5.12
3.17
PdgfdLSXLateral septal complex3.5
2.01
PdgfdMBMidbrain9.66
7.71
PdgfdMYMedulla9.45
8.28
PdgfdOLFOlfactory bulb17.26
10.93
PdgfdPPons11.98
11.57
PdgfdPALPallidum2.45
1.43
PdgfdRHPRetrohippocampal region23.59
18.67
PdgfdsAMYStriatum-like amygdalar nuclei10.17
5.44
PdgfdSTRStriatum3.99
2.18
PdgfdSTRdStriatum dorsal region2.46
1.39
PdgfdSTRvStriatum ventral region4.88
2.39
PdgfdTHThalamus4.82
3.08
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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