AutismKB 2.0

Annotation Detail for TET1


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Basic Information Top
Gene Symbol:TET1 ( CXXC6,FLJ10839,FLJ41442,KIAA1676,LCX,bA119F7.1 )
Gene Full Name: tet oncogene 1
Band: 10q21.3
Quick LinksEntrez ID:80312; OMIM: 607790; Uniprot ID:TET1_HUMAN; ENSEMBL ID: ENSG00000138336; HGNC ID: 29484
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst6 / 6231996
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor16 / 26384560
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal21 / 33603076
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine0 / 2344720 
kidney1 / 2117774
larynx1 / 2414541
liver0 / 2077430 
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P322756
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.94 ± 0.69
Basal Forebrain4.43 ± 0.29
Basal Part of Pons3.66 ± 0.62
Cerebellar Cortex4.61 ± 0.34
Cerebellar Nuclei3.81 ± 0.62
Claustrum4.05 ± 0.66
Epithalamus4.57 ± 0.4
Frontal Lobe3.71 ± 0.75
Globus Pallidus3.92 ± 0.94
Hypothalamus4.29 ± 0.57
Insula3.9 ± 0.48
Limbic Lobe3.62 ± 0.66
Mesencephalon4.14 ± 0.76
Myelencephalon3.95 ± 0.71
Occipital Lobe4.46 ± 0.57
Parietal Lobe4.05 ± 0.68
Pontine Tegmentum4.07 ± 0.69
Striatum3.94 ± 0.71
Subthalamus3.88 ± 0.33
Temporal Lobe3.73 ± 0.71
Thalamus4.19 ± 0.64
White Matter5.05 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cxxc6CBCerebellum30.59
49.38
Cxxc6CTXCerebral cortex100
97.59
Cxxc6HIPHippocampal region91.28
100
Cxxc6HPFHippocampal formation100
100
Cxxc6HYHypothalamus16.08
11.28
Cxxc6LSXLateral septal complex81.29
53.85
Cxxc6MBMidbrain22.12
17.54
Cxxc6MYMedulla22.82
21.24
Cxxc6OLFOlfactory bulb100
100
Cxxc6PPons18.53
16.15
Cxxc6PALPallidum43.75
36.02
Cxxc6RHPRetrohippocampal region100
94.95
Cxxc6sAMYStriatum-like amygdalar nuclei92.96
66.12
Cxxc6STRStriatum100
86.56
Cxxc6STRdStriatum dorsal region100
94.99
Cxxc6STRvStriatum ventral region100
87.09
Cxxc6THThalamus11.49
10.56
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018