AutismKB 2.0

Annotation Detail for LRRC27


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LRRC27 ( - )
Gene Full Name: leucine rich repeat containing 27
Band: 10q26.3
Quick LinksEntrez ID:80313; OMIM: NA; Uniprot ID:LRC27_HUMAN; ENSEMBL ID: ENSG00000148814; HGNC ID: 29346
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor6 / 26384522
glioma1 / 1068839
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal112 / 336030733
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain41 / 110098937
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine2 / 2344728
kidney5 / 21177723
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland1 / 2015549
skin0 / 2105740 
spleen2 / 5395237
stomach3 / 9661931
testis52 / 330442157
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_910_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.86 ± 0.8
Basal Forebrain3.6 ± 0.33
Basal Part of Pons3.39 ± 0.63
Cerebellar Cortex3.21 ± 0.54
Cerebellar Nuclei3.36 ± 0.58
Claustrum3.94 ± 0.56
Epithalamus4.32 ± 0.96
Frontal Lobe3.65 ± 0.61
Globus Pallidus3.33 ± 0.63
Hypothalamus3.31 ± 0.35
Insula3.79 ± 0.43
Limbic Lobe3.74 ± 0.61
Mesencephalon3.54 ± 0.53
Myelencephalon3.57 ± 0.63
Occipital Lobe3.38 ± 0.59
Parietal Lobe3.58 ± 0.67
Pontine Tegmentum3.64 ± 0.71
Striatum3.79 ± 0.77
Subthalamus3.27 ± 0.61
Temporal Lobe3.67 ± 0.56
Thalamus3.43 ± 0.56
White Matter3.37 ± 1.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lrrc27CBCerebellum2.93
3.75
Lrrc27CTXCerebral cortex3.35
2.41
Lrrc27HIPHippocampal region1.49
1.22
Lrrc27HPFHippocampal formation1.57
1.22
Lrrc27HYHypothalamus1.85
1.24
Lrrc27LSXLateral septal complex0.31
0.21
Lrrc27MBMidbrain5.19
4.63
Lrrc27MYMedulla15.89
17.13
Lrrc27OLFOlfactory bulb5.35
3.61
Lrrc27PPons11.41
12.55
Lrrc27PALPallidum2.12
1.74
Lrrc27RHPRetrohippocampal region1.72
1.23
Lrrc27sAMYStriatum-like amygdalar nuclei3.81
4.15
Lrrc27STRStriatum1.14
1.03
Lrrc27STRdStriatum dorsal region0.48
0.34
Lrrc27STRvStriatum ventral region1.36
0.83
Lrrc27THThalamus1.98
1.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018