AutismKB 2.0

Annotation Detail for EPC1


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Basic Information Top
Gene Symbol:EPC1 ( DKFZp781P2312,Epl1 )
Gene Full Name: enhancer of polycomb homolog 1 (Drosophila)
Band: 10p11.22
Quick LinksEntrez ID:80314; OMIM: 610999; Uniprot ID:EPC1_HUMAN; ENSEMBL ID: ENSG00000120616; HGNC ID: 19876
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus42 / 56401274
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult129 / 193912166
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult7 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor14 / 136302102
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal224 / 336030766
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal1 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor6 / 34366174
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia44 / 97250452
normal39 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood5 / 12347840
bone1 / 7165513
bone marrow0 / 488010 
brain41 / 110098937
cervix0 / 481710 
connective tissue5 / 14925533
ear5 / 16212308
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart7 / 8962678
intestine6 / 23447225
kidney9 / 21177742
larynx0 / 241450 
liver5 / 20774324
lung13 / 33697438
lymph0 / 442700 
lymph node2 / 9161021
mammary gland18 / 153271117
mouth4 / 6705259
muscle2 / 10771518
nerve2 / 15768126
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta13 / 28082546
prostate59 / 189345311
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis18 / 33044254
thymus5 / 8113161
thyroid9 / 47473189
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus10 / 23287842
vascular2 / 5178038
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus7 / 8113186
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix6 / 48171124
connective tissue44 / 149255294
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye0 / 2110540 
heart1 / 8962611
intestine9 / 23447238
kidney0 / 2117770 
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node4 / 9161043
mammary gland5 / 15327132
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland1 / 2015549
skin0 / 2105740 
spleen12 / 53952222
stomach8 / 9661982
testis1 / 3304423
thymus20 / 81131246
thyroid0 / 474730 
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9945_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.68 ± 0.55
Basal Forebrain5.75 ± 0.29
Basal Part of Pons5.74 ± 0.33
Cerebellar Cortex6.23 ± 0.28
Cerebellar Nuclei5.77 ± 0.37
Claustrum5.15 ± 0.52
Epithalamus6.27 ± 0.46
Frontal Lobe5.62 ± 0.45
Globus Pallidus5.52 ± 0.38
Hypothalamus5.57 ± 0.41
Insula5.69 ± 0.43
Limbic Lobe5.63 ± 0.46
Mesencephalon5.67 ± 0.52
Myelencephalon5.67 ± 0.5
Occipital Lobe5.88 ± 0.39
Parietal Lobe5.76 ± 0.39
Pontine Tegmentum5.71 ± 0.44
Striatum5.64 ± 0.52
Subthalamus5.54 ± 0.32
Temporal Lobe5.71 ± 0.36
Thalamus5.73 ± 0.38
White Matter6.61 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Epc1CBCerebellum16.71
19.45
Epc1CTXCerebral cortex14.68
11.63
Epc1HIPHippocampal region13.65
13.46
Epc1HPFHippocampal formation14.93
13.24
Epc1HYHypothalamus2.64
2.06
Epc1LSXLateral septal complex8.46
6.63
Epc1MBMidbrain6.7
6.41
Epc1MYMedulla19.21
19.69
Epc1OLFOlfactory bulb34.08
27.68
Epc1PPons8.09
7.69
Epc1PALPallidum5.61
4.48
Epc1RHPRetrohippocampal region17.67
13.26
Epc1sAMYStriatum-like amygdalar nuclei4.45
2.93
Epc1STRStriatum10.38
7.6
Epc1STRdStriatum dorsal region8.92
6.62
Epc1STRvStriatum ventral region19.02
12.89
Epc1THThalamus7.17
6.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011739 16 533 548 TPSLHDSDNDELSCRK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018