AutismKB 2.0

Annotation Detail for ADAM33


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Basic Information Top
Gene Symbol:ADAM33 ( C20orf153,DJ964F7.1,DKFZp434K0521,FLJ35308,FLJ36751,MGC149823,MGC71889 )
Gene Full Name: ADAM metallopeptidase domain 33
Band: 20p13
Quick LinksEntrez ID:80332; OMIM: 607114; Uniprot ID:ADA33_HUMAN; ENSEMBL ID: ENSG00000149451; HGNC ID: 15478
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult15 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach1 / 9661910
testis11 / 33044233
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus103 / 232878442
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P502343
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.1 ± 0.51
Basal Forebrain5.54 ± 0.37
Basal Part of Pons5.65 ± 0.2
Cerebellar Cortex4.98 ± 0.44
Cerebellar Nuclei5.41 ± 0.44
Claustrum5.32 ± 0.6
Epithalamus5.02 ± 0.45
Frontal Lobe5.06 ± 0.46
Globus Pallidus5.55 ± 0.5
Hypothalamus5.07 ± 0.6
Insula5.15 ± 0.47
Limbic Lobe5.05 ± 0.57
Mesencephalon5.23 ± 0.42
Myelencephalon5.18 ± 0.49
Occipital Lobe5.36 ± 0.44
Parietal Lobe5.1 ± 0.47
Pontine Tegmentum4.99 ± 0.39
Striatum5.33 ± 0.49
Subthalamus5.07 ± 0.37
Temporal Lobe5.09 ± 0.46
Thalamus5.17 ± 0.4
White Matter4.92 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adam33CBCerebellum1.51
1.39
Adam33CTXCerebral cortex21
10.35
Adam33HIPHippocampal region0.67
0.48
Adam33HPFHippocampal formation3.54
2.96
Adam33HYHypothalamus1.43
0.68
Adam33LSXLateral septal complex0.25
0.07
Adam33MBMidbrain4.26
2.47
Adam33MYMedulla8.04
6.6
Adam33OLFOlfactory bulb20.14
11.44
Adam33PPons4.58
2.92
Adam33PALPallidum0.47
0.31
Adam33RHPRetrohippocampal region8.15
6.55
Adam33sAMYStriatum-like amygdalar nuclei0.5
0.26
Adam33STRStriatum0.31
0.22
Adam33STRdStriatum dorsal region0.25
0.21
Adam33STRvStriatum ventral region0.46
0.28
Adam33THThalamus0.86
0.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018