AutismKB 2.0

Annotation Detail for DCAF11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:DCAF11 ( DKFZp779A1629,PRO2389,WDR23 )
Gene Full Name: DDB1 and CUL4 associated factor 11
Band: 14q12
Quick LinksEntrez ID:80344; OMIM: 613317; Uniprot ID:DCA11_HUMAN; ENSEMBL ID: ENSG00000100897; HGNC ID: 20258
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus109 / 564012193
neonate8 / 31097257
infant3 / 23620127
juvenile19 / 55556341
adult215 / 1939121110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor6 / 34366174
chondrosarcoma3 / 8282336
colorectal tumor12 / 114246105
esophageal tumor7 / 17290404
gastrointestinal tumor11 / 11936992
germ cell tumor35 / 263845132
glioma11 / 106883102
head and neck tumor49 / 136302359
kidney tumor9 / 68959130
leukemia23 / 95842239
liver tumor27 / 96359280
lung tumor7 / 10312767
lymphoma5 / 7175569
non-neoplasia15 / 97250154
normal558 / 3360307166
ovarian tumor10 / 76682130
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS48 / 125680381
prostate cancer8 / 10268077
retinoblastoma8 / 46356172
skin tumor6 / 12494948
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland9 / 33197271
ascites5 / 40015124
bladder8 / 29757268
blood15 / 123478121
bone3 / 7165541
bone marrow15 / 48801307
brain259 / 1100989235
cervix16 / 48171332
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus8 / 20209395
eye24 / 211054113
heart11 / 89626122
intestine27 / 234472115
kidney40 / 211777188
larynx1 / 2414541
liver59 / 207743284
lung23 / 33697468
lymph3 / 4427067
lymph node10 / 91610109
mammary gland13 / 15327184
mouth53 / 67052790
muscle13 / 107715120
nerve1 / 1576863
ovary14 / 102051137
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta35 / 280825124
prostate26 / 189345137
salivary gland2 / 2015599
skin32 / 210574151
spleen13 / 53952240
stomach4 / 9661941
testis37 / 330442111
thymus36 / 81131443
thyroid6 / 47473126
tonsil1 / 1699958
trachea16 / 52413305
umbilical cord1 / 1368073
uterus22 / 23287894
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201886_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.1
Adipocyte13.95
AdrenalCortex10.1
Adrenalgland11.35
Amygdala9.65
Appendix13.1
AtrioventricularNode6.35
BDCA4+_DentriticCells41.65
Bonemarrow48.1
BronchialEpithelialCells8.4
CD105+_Endothelial103
CD14+_Monocytes41.9
CD19+_BCells(neg._sel.)44.3
CD33+_Myeloid36.2
CD34+61.6
CD4+_Tcells30.4
CD56+_NKCells59.4
CD71+_EarlyErythroid283.45
CD8+_Tcells31.45
CardiacMyocytes12.65
Caudatenucleus11.95
Cerebellum9.25
CerebellumPeduncles11.6
CiliaryGanglion5.75
CingulateCortex10.85
Colorectaladenocarcinoma10.05
DorsalRootGanglion9.35
FetalThyroid18.25
Fetalbrain11.1
Fetalliver44.3
Fetallung20.95
GlobusPallidus8.65
Heart19.7
Hypothalamus11.15
Kidney25.95
Leukemia_chronicMyelogenousK-56211.45
Leukemia_promyelocytic-HL-6018.75
Leukemialymphoblastic(MOLT-4)22.4
Liver78.95
Lung12.85
Lymphnode14.15
Lymphoma_burkitts(Daudi)19.1
Lymphoma_burkitts(Raji)14.15
MedullaOblongata9.45
OccipitalLobe11.75
OlfactoryBulb8.75
Ovary7.7
Pancreas14.8
PancreaticIslet13.6
ParietalLobe10.5
Pituitary12.75
Placenta10.6
Pons11.9
PrefrontalCortex14.35
Prostate17.4
Salivarygland8.9
SkeletalMuscle8.2
Skin11.1
SmoothMuscle8.55
Spinalcord11.2
SubthalamicNucleus12.85
SuperiorCervicalGanglion14.15
TemporalLobe11.05
Testis12.25
TestisGermCell8.5
TestisIntersitial9.25
TestisLeydigCell7.4
TestisSeminiferousTubule10.55
Thalamus16.6
Thymus18.45
Thyroid22.2
Tongue10.4
Tonsil10.65
Trachea8.45
TrigeminalGanglion12.05
Uterus8.15
UterusCorpus7.4
WholeBlood15.3
Wholebrain15.85
colon9.25
pineal_day24.36
pineal_night19.38
retina11.625
small_intestine9.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P117424
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.4 ± 0.77
Basal Forebrain6.49 ± 0.24
Basal Part of Pons6.83 ± 0.49
Cerebellar Cortex6.64 ± 0.5
Cerebellar Nuclei6.53 ± 0.57
Claustrum6.11 ± 0.67
Epithalamus6.43 ± 0.64
Frontal Lobe6.87 ± 0.47
Globus Pallidus6 ± 0.38
Hypothalamus6.75 ± 0.42
Insula7.02 ± 0.16
Limbic Lobe6.66 ± 0.74
Mesencephalon6.47 ± 0.47
Myelencephalon6.65 ± 0.57
Occipital Lobe5.97 ± 0.7
Parietal Lobe6.67 ± 0.49
Pontine Tegmentum6.54 ± 0.48
Striatum6.18 ± 0.59
Subthalamus6.84 ± 0.53
Temporal Lobe6.99 ± 0.44
Thalamus6.59 ± 0.44
White Matter5.77 ± 0.4
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00130933 22 30 51 SEEEEEEDEDVDLAQVLAYLLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved