AutismKB 2.0

Annotation Detail for AKNA


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Basic Information Top
Gene Symbol:AKNA ( FLJ31001,FLJ33184,KIAA1968,RP11-82I1.4 )
Gene Full Name: AT-hook transcription factor
Band: 9q32
Quick LinksEntrez ID:80709; OMIM: 605729; Uniprot ID:AKNA_HUMAN; ENSEMBL ID: ENSG00000106948; HGNC ID: 24108
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia27 / 95842281
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma6 / 7175583
non-neoplasia0 / 972500 
normal100 / 336030729
ovarian tumor6 / 7668278
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma4 / 4635686
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood13 / 123478105
bone0 / 716550 
bone marrow7 / 48801143
brain13 / 110098911
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye14 / 21105466
heart3 / 8962633
intestine5 / 23447221
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph3 / 4427067
lymph node47 / 91610513
mammary gland1 / 1532716
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary8 / 10205178
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate6 / 18934531
salivary gland0 / 201550 
skin1 / 2105744
spleen3 / 5395255
stomach0 / 966190 
testis3 / 3304429
thymus5 / 8113161
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_465_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.98 ± 1.16
Basal Forebrain2.24 ± 0.3
Basal Part of Pons2.03 ± 0.61
Cerebellar Cortex1.92 ± 0.59
Cerebellar Nuclei2.54 ± 0.62
Claustrum2.72 ± 0.74
Epithalamus2.84 ± 0.51
Frontal Lobe2.19 ± 0.78
Globus Pallidus3.93 ± 1.22
Hypothalamus2.19 ± 0.74
Insula2.04 ± 0.77
Limbic Lobe2.35 ± 0.73
Mesencephalon2.47 ± 0.86
Myelencephalon2.47 ± 0.81
Occipital Lobe2.14 ± 0.86
Parietal Lobe2.49 ± 0.88
Pontine Tegmentum2.38 ± 0.77
Striatum2.88 ± 0.79
Subthalamus2.15 ± 0.67
Temporal Lobe2.36 ± 0.77
Thalamus2.26 ± 0.8
White Matter3.13 ± 0.76
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039378 16 1071 1086 AGRDQAICELQEEVSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018