AutismKB 2.0

Annotation Detail for ARHGAP39


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Basic Information Top
Gene Symbol:ARHGAP39 ( CrGAP,KIAA1688,Vilse )
Gene Full Name: Rho GTPase activating protein 39
Band: 8q24.3
Quick LinksEntrez ID:80728; OMIM: NA; Uniprot ID:RHG39_HUMAN; ENSEMBL ID: ENSG00000147799; HGNC ID: 29351
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma8 / 10688374
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal43 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain29 / 110098926
cervix2 / 4817141
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1375_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.5 ± 1.18
Basal Forebrain2.69 ± 0.34
Basal Part of Pons2.51 ± 0.4
Cerebellar Cortex2.45 ± 0.82
Cerebellar Nuclei3.3 ± 0.68
Claustrum3.47 ± 0.78
Epithalamus2.6 ± 1.43
Frontal Lobe2.66 ± 0.93
Globus Pallidus3.73 ± 0.59
Hypothalamus2.77 ± 1.02
Insula2.73 ± 0.71
Limbic Lobe3.07 ± 0.96
Mesencephalon3.11 ± 0.92
Myelencephalon2.95 ± 0.83
Occipital Lobe2.99 ± 1.05
Parietal Lobe3 ± 0.95
Pontine Tegmentum2.88 ± 0.75
Striatum3.59 ± 0.98
Subthalamus3.14 ± 0.19
Temporal Lobe2.85 ± 0.95
Thalamus2.73 ± 0.79
White Matter3.12 ± 0.65
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D15Wsu169eCBCerebellum7.73
8.36
D15Wsu169eCTXCerebral cortex55.97
41.89
D15Wsu169eHIPHippocampal region100
100
D15Wsu169eHPFHippocampal formation80.71
100
D15Wsu169eHYHypothalamus3.67
2.74
D15Wsu169eLSXLateral septal complex54.56
41.44
D15Wsu169eMBMidbrain7.25
6.65
D15Wsu169eMYMedulla11.65
12.14
D15Wsu169eOLFOlfactory bulb37.81
29.45
D15Wsu169ePPons9.19
9.27
D15Wsu169ePALPallidum7.68
6.43
D15Wsu169eRHPRetrohippocampal region41.8
35.13
D15Wsu169esAMYStriatum-like amygdalar nuclei9.37
6.44
D15Wsu169eSTRStriatum7.69
5.65
D15Wsu169eSTRdStriatum dorsal region3.61
2.83
D15Wsu169eSTRvStriatum ventral region5.83
3.6
D15Wsu169eTHThalamus5.17
5.97
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018