AutismKB 2.0

Annotation Detail for TAS1R2


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Basic Information Top
Gene Symbol:TAS1R2 ( GPR71,T1R2,TR2 )
Gene Full Name: taste receptor, type 1, member 2
Band: 1p36.13
Quick LinksEntrez ID:80834; OMIM: 606226; Uniprot ID:TS1R2_HUMAN; ENSEMBL ID: ENSG00000179002; HGNC ID: 14905
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14842_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.21 ± 1.05
Basal Forebrain1.77 ± 0.2
Basal Part of Pons1.49 ± 0.35
Cerebellar Cortex1.62 ± 0.78
Cerebellar Nuclei2.04 ± 0.74
Claustrum2.65 ± 1.16
Epithalamus1.44 ± 0.72
Frontal Lobe1.58 ± 0.63
Globus Pallidus2.39 ± 0.61
Hypothalamus1.85 ± 0.68
Insula1.59 ± 0.45
Limbic Lobe1.75 ± 0.59
Mesencephalon1.9 ± 0.71
Myelencephalon1.78 ± 0.68
Occipital Lobe1.8 ± 0.65
Parietal Lobe1.8 ± 0.76
Pontine Tegmentum1.79 ± 0.67
Striatum1.86 ± 0.5
Subthalamus2 ± 0.75
Temporal Lobe1.65 ± 0.65
Thalamus1.72 ± 0.58
White Matter2.23 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tas1r2CBCerebellum1.63
1.81
Tas1r2CTXCerebral cortex0.27
0.28
Tas1r2HIPHippocampal region0.15
0.23
Tas1r2HPFHippocampal formation0.17
0.23
Tas1r2HYHypothalamus0.08
0.65
Tas1r2LSXLateral septal complex0
0
Tas1r2MBMidbrain0.06
0.08
Tas1r2MYMedulla0.29
0.4
Tas1r2OLFOlfactory bulb1.09
1.2
Tas1r2PPons0.07
0.07
Tas1r2PALPallidum0
0
Tas1r2RHPRetrohippocampal region0.19
0.18
Tas1r2sAMYStriatum-like amygdalar nuclei0.27
0.13
Tas1r2STRStriatum0.27
0.19
Tas1r2STRdStriatum dorsal region0.31
0.24
Tas1r2STRvStriatum ventral region0
0
Tas1r2THThalamus0.02
0.02
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018