AutismKB 2.0

Annotation Detail for SETD7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SETD7 ( FLJ21193,KIAA1717,KMT7,SET7,SET7/9,SET9 )
Gene Full Name: SET domain containing (lysine methyltransferase) 7
Band: 4q31.1
Quick LinksEntrez ID:80854; OMIM: 606594; Uniprot ID:SETD7_HUMAN; ENSEMBL ID: ENSG00000145391; HGNC ID: 30412
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor7 / 26384526
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma3 / 7175541
non-neoplasia6 / 9725061
normal141 / 336030741
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone5 / 7165569
bone marrow0 / 488010 
brain41 / 110098937
cervix2 / 4817141
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine13 / 23447255
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung9 / 33697426
lymph3 / 4427067
lymph node10 / 91610109
mammary gland12 / 15327178
mouth2 / 6705229
muscle5 / 10771546
nerve2 / 15768126
ovary2 / 10205119
pancreas10 / 21481246
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate10 / 18934552
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach1 / 9661910
testis9 / 33044227
thymus1 / 8113112
thyroid2 / 4747342
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus17 / 23287872
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P251841
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.94 ± 0.54
Basal Forebrain5.26 ± 0.28
Basal Part of Pons5.32 ± 0.27
Cerebellar Cortex5.59 ± 0.25
Cerebellar Nuclei5.75 ± 0.37
Claustrum4.82 ± 0.66
Epithalamus5.25 ± 0.45
Frontal Lobe5.41 ± 0.38
Globus Pallidus6.06 ± 0.22
Hypothalamus5.15 ± 0.47
Insula5.27 ± 0.23
Limbic Lobe5.27 ± 0.42
Mesencephalon5.47 ± 0.46
Myelencephalon5.36 ± 0.43
Occipital Lobe5.52 ± 0.33
Parietal Lobe5.61 ± 0.51
Pontine Tegmentum5.4 ± 0.48
Striatum5.13 ± 0.41
Subthalamus5.45 ± 0.85
Temporal Lobe5.28 ± 0.39
Thalamus5.64 ± 0.41
White Matter6.5 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Setd7CBCerebellum54.06
100
Setd7CTXCerebral cortex100
98.44
Setd7HIPHippocampal region77.88
100
Setd7HPFHippocampal formation81.04
96.59
Setd7HYHypothalamus41.33
38.38
Setd7LSXLateral septal complex48.98
39.74
Setd7MBMidbrain54.03
60.24
Setd7MYMedulla66.02
96.61
Setd7OLFOlfactory bulb92.23
94.44
Setd7PPons51.97
71.76
Setd7PALPallidum46.37
56.93
Setd7RHPRetrohippocampal region93.56
93.58
Setd7sAMYStriatum-like amygdalar nuclei44.68
43.56
Setd7STRStriatum44.54
41.91
Setd7STRdStriatum dorsal region43.57
42.47
Setd7STRvStriatum ventral region45.88
40.2
Setd7THThalamus97.98
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024201 18 295 312 ANHSFTPNCIYDMFVHPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018