Annotation Detail for HMGA2
Basic Information Top
| Gene Symbol: | HMGA2 ( BABL,HMGI-C,HMGIC,LIPO,STQTL9 ) |
|---|---|
| Gene Full Name: | high mobility group AT-hook 2 |
| Band: | 12q14.3 |
| Quick Links | Entrez ID:8091; OMIM: 600698; Uniprot ID:HMGA2_HUMAN; ENSEMBL ID: ENSG00000149948; HGNC ID: 5009 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.505924
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 45 / 70761 | 635 |  |
| blastocyst | 9 / 62319 | 144 |  |
| fetus | 9 / 564012 | 15 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 61 / 1939121 | 31 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 10 / 82823 | 120 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 37 / 263845 | 140 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 5 / 136302 | 36 | |
| kidney tumor | 7 / 68959 | 101 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 13 / 96359 | 134 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 119 / 3360307 | 35 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 15 / 46356 | 323 | |
| skin tumor | 8 / 124949 | 64 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 5 / 40015 | 124 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 9 / 149255 | 60 | |
| ear | 2 / 16212 | 123 | |
| embryonic tissue | 81 / 215722 | 375 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 15 / 211054 | 71 | |
| heart | 1 / 89626 | 11 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 10 / 211777 | 47 | |
| larynx | 0 / 24145 | 0 | |
| liver | 14 / 207743 | 67 | |
| lung | 8 / 336974 | 23 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 4 / 153271 | 26 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 3 / 280825 | 10 |  |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 19 / 210574 | 90 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 30 / 330442 | 90 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 3 / 47473 | 63 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 208025_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.95 | |
| Adipocyte | 4.1 | |
| AdrenalCortex | 4.55 | |
| Adrenalgland | 3.7 | |
| Amygdala | 4.35 | |
| Appendix | 4.65 | |
| AtrioventricularNode | 3.55 | |
| BDCA4+_DentriticCells | 4.35 | |
| Bonemarrow | 4.1 | |
| BronchialEpithelialCells | 114.7 | |
| CD105+_Endothelial | 4.6 | |
| CD14+_Monocytes | 4.4 | |
| CD19+_BCells(neg._sel.) | 4.9 | |
| CD33+_Myeloid | 5.1 | |
| CD34+ | 10.45 | |
| CD4+_Tcells | 4.4 | |
| CD56+_NKCells | 4.8 | |
| CD71+_EarlyErythroid | 3.9 | |
| CD8+_Tcells | 3.9 | |
| CardiacMyocytes | 9.5 | |
| Caudatenucleus | 3.7 | |
| Cerebellum | 3.4 | |
| CerebellumPeduncles | 4.8 | |
| CiliaryGanglion | 3.1 | |
| CingulateCortex | 4.25 | |
| Colorectaladenocarcinoma | 22.4 | |
| DorsalRootGanglion | 3.25 | |
| FetalThyroid | 4.1 | |
| Fetalbrain | 4.15 | |
| Fetalliver | 8.1 | |
| Fetallung | 3.45 | |
| GlobusPallidus | 3.3 | |
| Heart | 6.05 | |
| Hypothalamus | 4.45 | |
| Kidney | 3.4 | |
| Leukemia_chronicMyelogenousK-562 | 3.75 | |
| Leukemia_promyelocytic-HL-60 | 3.65 | |
| Leukemialymphoblastic(MOLT-4) | 3.35 | |
| Liver | 5.5 | |
| Lung | 4.6 | |
| Lymphnode | 3.6 | |
| Lymphoma_burkitts(Daudi) | 5.5 | |
| Lymphoma_burkitts(Raji) | 5.8 | |
| MedullaOblongata | 3.8 | |
| OccipitalLobe | 3.7 | |
| OlfactoryBulb | 3.3 | |
| Ovary | 2.85 | |
| Pancreas | 3.45 | |
| PancreaticIslet | 4.45 | |
| ParietalLobe | 4.35 | |
| Pituitary | 4.85 | |
| Placenta | 4.2 | |
| Pons | 4 | |
| PrefrontalCortex | 5.2 | |
| Prostate | 4.8 | |
| Salivarygland | 3.4 | |
| SkeletalMuscle | 5.2 | |
| Skin | 3.35 | |
| SmoothMuscle | 15.5 | |
| Spinalcord | 4.4 | |
| SubthalamicNucleus | 4.1 | |
| SuperiorCervicalGanglion | 4.9 | |
| TemporalLobe | 3.8 | |
| Testis | 3.6 | |
| TestisGermCell | 3.5 | |
| TestisIntersitial | 3.55 | |
| TestisLeydigCell | 4.15 | |
| TestisSeminiferousTubule | 3.6 | |
| Thalamus | 4.2 | |
| Thymus | 3.2 | |
| Thyroid | 5.2 | |
| Tongue | 4.1 | |
| Tonsil | 4.05 | |
| Trachea | 3.5 | |
| TrigeminalGanglion | 4.3 | |
| Uterus | 3.4 | |
| UterusCorpus | 3.75 | |
| WholeBlood | 4.55 | |
| Wholebrain | 3.4 | |
| colon | 4.25 | |
| pineal_day | 5.16 | |
| pineal_night | 5.3 | |
| retina | 5.05 | |
| small_intestine | 4 | |
- Probe name: A_24_P85099
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.45 ± 1.08 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.79 ± 0.23 | |
| Basal Part of Pons | 1.59 ± 0.62 | |
| Cerebellar Cortex | 1.9 ± 1 | |
| Cerebellar Nuclei | 2.18 ± 0.8 | |
| Claustrum | 2.85 ± 0.96 | |
| Epithalamus | 1.59 ± 0.69 | |
| Frontal Lobe | 1.81 ± 0.81 | |
| Globus Pallidus | 2.34 ± 0.33 | |
| Hypothalamus | 1.92 ± 0.76 | |
| Insula | 1.71 ± 0.72 | |
| Limbic Lobe | 1.87 ± 0.78 | |
| Mesencephalon | 2.06 ± 0.77 | |
| Myelencephalon | 1.95 ± 0.83 | |
| Occipital Lobe | 2.07 ± 0.82 | |
| Parietal Lobe | 2 ± 0.92 | |
| Pontine Tegmentum | 1.98 ± 0.73 | |
| Striatum | 1.93 ± 0.61 | |
| Subthalamus | 2 ± 0.79 | |
| Temporal Lobe | 1.77 ± 0.77 | |
| Thalamus | 1.9 ± 0.7 | |
| White Matter | 2.12 ± 0.11 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Hmga2 | CB | Cerebellum | 27.83 | |
| 40.55 | | |||
| Hmga2 | CTX | Cerebral cortex | 11.92 | |
| 9.78 | | |||
| Hmga2 | HIP | Hippocampal region | 6.08 | |
| 7.96 | | |||
| Hmga2 | HPF | Hippocampal formation | 5.28 | |
| 5.87 | | |||
| Hmga2 | HY | Hypothalamus | 17.12 | |
| 14.09 | | |||
| Hmga2 | LSX | Lateral septal complex | 1.74 | |
| 2.64 | | |||
| Hmga2 | MB | Midbrain | 15.17 | |
| 13.71 | | |||
| Hmga2 | MY | Medulla | 16.21 | |
| 16.24 | | |||
| Hmga2 | OLF | Olfactory bulb | 34.94 | |
| 38.91 | | |||
| Hmga2 | P | Pons | 16.68 | |
| 14.61 | | |||
| Hmga2 | PAL | Pallidum | 16.61 | |
| 13.89 | | |||
| Hmga2 | RHP | Retrohippocampal region | 3.77 | |
| 2.88 | | |||
| Hmga2 | sAMY | Striatum-like amygdalar nuclei | 2.1 | |
| 1.29 | | |||
| Hmga2 | STR | Striatum | 12.22 | |
| 10.81 | | |||
| Hmga2 | STRd | Striatum dorsal region | 9.44 | |
| 8.33 | | |||
| Hmga2 | STRv | Striatum ventral region | 34.32 | |
| 28.62 | | |||
| Hmga2 | TH | Thalamus | 13.75 | |
| 12.23 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00131621 | 22 | 5 | 26 | GEGAGQPSTSAQGQPAAPAPQK | Peptide Atlas |