AutismKB 2.0

Annotation Detail for GPR68


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Basic Information Top
Gene Symbol:GPR68 ( GPR12A,MGC111379,MGC156983,OGR1 )
Gene Full Name: G protein-coupled receptor 68
Band: 14q32.11
Quick LinksEntrez ID:8111; OMIM: 601404; Uniprot ID:OGR1_HUMAN; ENSEMBL ID: ENSG00000119714; HGNC ID: 4519
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal24 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211249_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.25
Adipocyte4.4
AdrenalCortex5.25
Adrenalgland3.75
Amygdala4.6
Appendix4.4
AtrioventricularNode3.5
BDCA4+_DentriticCells4.85
Bonemarrow4.45
BronchialEpithelialCells4.4
CD105+_Endothelial4.45
CD14+_Monocytes4.75
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid5.55
CD34+5.7
CD4+_Tcells4.8
CD56+_NKCells5.25
CD71+_EarlyErythroid4.15
CD8+_Tcells4.35
CardiacMyocytes5.6
Caudatenucleus4
Cerebellum3.55
CerebellumPeduncles5.05
CiliaryGanglion3.1
CingulateCortex4.5
Colorectaladenocarcinoma4.45
DorsalRootGanglion3.35
FetalThyroid4.25
Fetalbrain4.45
Fetalliver3.8
Fetallung3.6
GlobusPallidus3.25
Heart5.6
Hypothalamus4.55
Kidney3.7
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.65
Liver6.05
Lung4.85
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.65
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4
OccipitalLobe4
OlfactoryBulb3.55
Ovary2.95
Pancreas3.65
PancreaticIslet5.65
ParietalLobe4.65
Pituitary5.2
Placenta4.25
Pons4.2
PrefrontalCortex5.55
Prostate5.25
Salivarygland3.55
SkeletalMuscle16
Skin3.3
SmoothMuscle5.05
Spinalcord4.75
SubthalamicNucleus4
SuperiorCervicalGanglion4.9
TemporalLobe4
Testis3.75
TestisGermCell3.55
TestisIntersitial3.7
TestisLeydigCell4.35
TestisSeminiferousTubule3.75
Thalamus4.45
Thymus3.45
Thyroid5.5
Tongue4.4
Tonsil4.75
Trachea4.35
TrigeminalGanglion4.4
Uterus3.6
UterusCorpus4.1
WholeBlood4.85
Wholebrain3.8
colon4.5
pineal_day5.26
pineal_night5.14
retina5.35
small_intestine4.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P931443
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.63 ± 0.55
Basal Forebrain5.43 ± 0.43
Basal Part of Pons6.56 ± 0.64
Cerebellar Cortex7.09 ± 0.26
Cerebellar Nuclei5.71 ± 0.84
Claustrum6.35 ± 0.63
Epithalamus6.1 ± 1.11
Frontal Lobe6.81 ± 0.57
Globus Pallidus4.25 ± 1.18
Hypothalamus7.47 ± 1.18
Insula7.07 ± 0.51
Limbic Lobe6.21 ± 1.02
Mesencephalon5.9 ± 1.05
Myelencephalon6.13 ± 1.22
Occipital Lobe5.13 ± 0.93
Parietal Lobe5.98 ± 0.61
Pontine Tegmentum6.2 ± 1.33
Striatum3.53 ± 1.11
Subthalamus6.47 ± 0.11
Temporal Lobe6.52 ± 0.58
Thalamus6.35 ± 1.1
White Matter3.06 ± 0.91
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gpr68CBCerebellum20.23
20.81
Gpr68CTXCerebral cortex36.69
24.44
Gpr68HIPHippocampal region30.97
32.92
Gpr68HPFHippocampal formation31.59
28.91
Gpr68HYHypothalamus15.21
10.1
Gpr68LSXLateral septal complex3.82
2.26
Gpr68MBMidbrain16.88
13.7
Gpr68MYMedulla28.8
27.77
Gpr68OLFOlfactory bulb47.83
38.09
Gpr68PPons26.39
25.2
Gpr68PALPallidum25.19
20.09
Gpr68RHPRetrohippocampal region35.52
24.01
Gpr68sAMYStriatum-like amygdalar nuclei23.04
15.76
Gpr68STRStriatum23.01
15.49
Gpr68STRdStriatum dorsal region21.28
13.85
Gpr68STRvStriatum ventral region35.29
23.81
Gpr68THThalamus23.74
17.42
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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