AutismKB 2.0

Annotation Detail for ANP32A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANP32A ( C15orf1,I1PP2A,LANP,MAPM,MGC119787,MGC150373,PHAP1,PHAPI,PP32 )
Gene Full Name: acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Band: 15q23
Quick LinksEntrez ID:8125; OMIM: 600832; Uniprot ID:AN32A_HUMAN; ENSEMBL ID: ENSG00000140350; HGNC ID: 13233
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst10 / 62319160
fetus70 / 564012124
neonate0 / 310970 
infant11 / 23620465
juvenile16 / 55556287
adult183 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor10 / 94178106
cervical tumor9 / 34366261
chondrosarcoma7 / 8282384
colorectal tumor16 / 114246140
esophageal tumor4 / 17290231
gastrointestinal tumor14 / 119369117
germ cell tumor43 / 263845162
glioma3 / 10688328
head and neck tumor13 / 13630295
kidney tumor7 / 68959101
leukemia15 / 95842156
liver tumor14 / 96359145
lung tumor9 / 10312787
lymphoma22 / 71755306
non-neoplasia2 / 9725020
normal366 / 3360307108
ovarian tumor6 / 7668278
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS34 / 125680270
prostate cancer8 / 10268077
retinoblastoma10 / 46356215
skin tumor7 / 12494956
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor19 / 90257210
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites10 / 40015249
bladder10 / 29757336
blood13 / 123478105
bone5 / 7165569
bone marrow7 / 48801143
brain96 / 110098987
cervix9 / 48171186
connective tissue8 / 14925553
ear4 / 16212246
embryonic tissue58 / 215722268
esophagus4 / 20209197
eye31 / 211054146
heart18 / 89626200
intestine27 / 234472115
kidney23 / 211777108
larynx7 / 24145289
liver23 / 207743110
lung28 / 33697483
lymph16 / 44270361
lymph node8 / 9161087
mammary gland18 / 153271117
mouth3 / 6705244
muscle7 / 10771564
nerve2 / 15768126
ovary9 / 10205188
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland4 / 16585241
placenta32 / 280825113
prostate17 / 18934589
salivary gland2 / 2015599
skin13 / 21057461
spleen7 / 53952129
stomach4 / 9661941
testis22 / 33044266
thymus12 / 81131147
thyroid5 / 47473105
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus26 / 232878111
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201043_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts185.75
Adipocyte29.3
AdrenalCortex35.7
Adrenalgland26.55
Amygdala26.1
Appendix32.5
AtrioventricularNode27
BDCA4+_DentriticCells85.4
Bonemarrow37.75
BronchialEpithelialCells59.15
CD105+_Endothelial41.7
CD14+_Monocytes39.6
CD19+_BCells(neg._sel.)51.05
CD33+_Myeloid41.25
CD34+41
CD4+_Tcells42.4
CD56+_NKCells39.45
CD71+_EarlyErythroid52.65
CD8+_Tcells24.95
CardiacMyocytes88.2
Caudatenucleus26.7
Cerebellum46.55
CerebellumPeduncles40.65
CiliaryGanglion22.35
CingulateCortex32.5
Colorectaladenocarcinoma38.9
DorsalRootGanglion24.3
FetalThyroid37.4
Fetalbrain30.5
Fetalliver34.35
Fetallung24.7
GlobusPallidus23.45
Heart49.4
Hypothalamus21.95
Kidney29.5
Leukemia_chronicMyelogenousK-56233.85
Leukemia_promyelocytic-HL-6057
Leukemialymphoblastic(MOLT-4)39.4
Liver41.9
Lung28.3
Lymphnode21.4
Lymphoma_burkitts(Daudi)49.8
Lymphoma_burkitts(Raji)51.15
MedullaOblongata21.85
OccipitalLobe21.55
OlfactoryBulb36.1
Ovary22.9
Pancreas24.1
PancreaticIslet30.85
ParietalLobe33.85
Pituitary51.35
Placenta30.35
Pons29.4
PrefrontalCortex38.85
Prostate29.8
Salivarygland22
SkeletalMuscle43.8
Skin24.35
SmoothMuscle56.2
Spinalcord30.85
SubthalamicNucleus25.45
SuperiorCervicalGanglion47.35
TemporalLobe30.6
Testis27.2
TestisGermCell20.2
TestisIntersitial24.3
TestisLeydigCell31.45
TestisSeminiferousTubule23.6
Thalamus28.45
Thymus94.5
Thyroid21.35
Tongue31.3
Tonsil30.3
Trachea28.1
TrigeminalGanglion32.45
Uterus18.25
UterusCorpus28.45
WholeBlood100.95
Wholebrain20.15
colon101.85
pineal_day34.66
pineal_night36.16
retina43.65
small_intestine70.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P3242
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.43 ± 0.38
Basal Forebrain7.58 ± 0.25
Basal Part of Pons7.33 ± 0.31
Cerebellar Cortex7.87 ± 0.2
Cerebellar Nuclei7.47 ± 0.27
Claustrum7.06 ± 0.41
Epithalamus7.56 ± 0.25
Frontal Lobe7.52 ± 0.29
Globus Pallidus7.36 ± 0.36
Hypothalamus7.23 ± 0.23
Insula7.59 ± 0.33
Limbic Lobe7.65 ± 0.31
Mesencephalon7.49 ± 0.34
Myelencephalon7.53 ± 0.36
Occipital Lobe7.8 ± 0.26
Parietal Lobe7.49 ± 0.35
Pontine Tegmentum7.55 ± 0.34
Striatum7.88 ± 0.41
Subthalamus7.64 ± 0.1
Temporal Lobe7.51 ± 0.24
Thalamus7.5 ± 0.28
White Matter7.08 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anp32aCBCerebellum26.19
22.41
Anp32aCTXCerebral cortex26.73
20
Anp32aHIPHippocampal region20.43
14.05
Anp32aHPFHippocampal formation19.72
15.58
Anp32aHYHypothalamus2.14
1.36
Anp32aLSXLateral septal complex11.58
8.18
Anp32aMBMidbrain6.52
6.44
Anp32aMYMedulla22.06
20.71
Anp32aOLFOlfactory bulb29.72
18.46
Anp32aPPons9.13
8.03
Anp32aPALPallidum4.28
3.4
Anp32aRHPRetrohippocampal region19.71
16.62
Anp32asAMYStriatum-like amygdalar nuclei4.62
2.58
Anp32aSTRStriatum8.21
5.54
Anp32aSTRdStriatum dorsal region5.74
3.97
Anp32aSTRvStriatum ventral region16.16
10.16
Anp32aTHThalamus5.88
4.03
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AN32A_HUMAN_0 0 0 0 DLSTIEPLK PRIDE
AN32A_HUMAN_0 0 0 0 LLPQLTYLDGYDR PRIDE
AN32A_HUMAN_0 0 0 0 SLDLFNCEVTNLNDYR PRIDE
AN32A_HUMAN_0 0 0 0 VSGGLEVLAEK PRIDE
AN32A_HUMAN_101 10 101 110 DLSTIEPLKK PRIDE
AN32A_HUMAN_101 15 101 115 DLSTIEPLKKLENLK PRIDE
AN32A_HUMAN_101 9 101 109 DLSTIEPLK PRIDE
AN32A_HUMAN_116 16 116 131 SLDLFNCEVTNLNDYR PRIDE
AN32A_HUMAN_116 21 116 136 SLDLFNCEVTNLNDYRENVFK PRIDE
AN32A_HUMAN_137 13 137 149 LLPQLTYLDGYDR PRIDE
AN32A_HUMAN_137 16 137 152 LLPQLTYLDGYDRDDK PRIDE
AN32A_HUMAN_16 13 16 28 PSDVKELVLDNSR PRIDE
AN32A_HUMAN_20 8 20 27 ELVLDNSR PRIDE
AN32A_HUMAN_75 11 75 85 VSGGLEVLAEK PRIDE
AN32A_HUMAN_75 24 75 98 VSGGLEVLAEKCPNLTHLNLSGNK PRIDE
AN32A_HUMAN_86 13 86 98 CPNLTHLNLSGNK PRIDE
PAp00001270 13 87 99 CPNLTHLNLSGNK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved