AutismKB 2.0

Annotation Detail for NPRL3


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Basic Information Top
Gene Symbol:NPRL3 ( C16orf35,CGTHBA,HS-40,MARE,NPR3,RMD11 )
Gene Full Name: nitrogen permease regulator-like 3 (S. cerevisiae)
Band: 16p13.3
Quick LinksEntrez ID:8131; OMIM: 600928; Uniprot ID:NPRL3_HUMAN; ENSEMBL ID: ENSG00000103148; HGNC ID: 14124
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus33 / 56401258
neonate2 / 3109764
infant2 / 2362084
juvenile4 / 5555671
adult228 / 1939121117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor10 / 11936983
germ cell tumor29 / 263845109
glioma6 / 10688356
head and neck tumor6 / 13630244
kidney tumor7 / 68959101
leukemia111 / 958421158
liver tumor2 / 9635920
lung tumor18 / 103127174
lymphoma5 / 7175569
non-neoplasia3 / 9725030
normal214 / 336030763
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer9 / 10268087
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites5 / 40015124
bladder1 / 2975733
blood12 / 12347897
bone5 / 7165569
bone marrow102 / 488012090
brain48 / 110098943
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye31 / 211054146
heart7 / 8962678
intestine17 / 23447272
kidney17 / 21177780
larynx1 / 2414541
liver4 / 20774319
lung40 / 336974118
lymph1 / 4427022
lymph node12 / 91610130
mammary gland17 / 153271110
mouth3 / 6705244
muscle3 / 10771527
nerve0 / 157680 
ovary9 / 10205188
pancreas12 / 21481255
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate13 / 18934568
salivary gland0 / 201550 
skin8 / 21057437
spleen8 / 53952148
stomach8 / 9661982
testis17 / 33044251
thymus0 / 811310 
thyroid4 / 4747384
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210672_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts107.6
Adipocyte16.25
AdrenalCortex15.05
Adrenalgland11.25
Amygdala21
Appendix11.4
AtrioventricularNode5.3
BDCA4+_DentriticCells19.6
Bonemarrow28.8
BronchialEpithelialCells13.7
CD105+_Endothelial276.8
CD14+_Monocytes14.1
CD19+_BCells(neg._sel.)14.25
CD33+_Myeloid15.2
CD34+42.9
CD4+_Tcells14.6
CD56+_NKCells25.45
CD71+_EarlyErythroid385.1
CD8+_Tcells13.6
CardiacMyocytes21.95
Caudatenucleus14.7
Cerebellum19.1
CerebellumPeduncles15.95
CiliaryGanglion7.1
CingulateCortex14.2
Colorectaladenocarcinoma16.75
DorsalRootGanglion9.9
FetalThyroid18
Fetalbrain14.65
Fetalliver29.05
Fetallung11.95
GlobusPallidus10.45
Heart34.3
Hypothalamus15.25
Kidney11.45
Leukemia_chronicMyelogenousK-56231.85
Leukemia_promyelocytic-HL-6014.4
Leukemialymphoblastic(MOLT-4)18.2
Liver33.55
Lung46.15
Lymphnode12.05
Lymphoma_burkitts(Daudi)28.4
Lymphoma_burkitts(Raji)22.05
MedullaOblongata11.95
OccipitalLobe15.6
OlfactoryBulb10.8
Ovary8.85
Pancreas11.3
PancreaticIslet16.85
ParietalLobe15.1
Pituitary16.15
Placenta15.9
Pons13
PrefrontalCortex50.15
Prostate28.25
Salivarygland10.3
SkeletalMuscle19.25
Skin7.65
SmoothMuscle26.85
Spinalcord14.4
SubthalamicNucleus12.8
SuperiorCervicalGanglion15.85
TemporalLobe11.5
Testis19.95
TestisGermCell14.15
TestisIntersitial11.15
TestisLeydigCell12.95
TestisSeminiferousTubule11.95
Thalamus13.7
Thymus18
Thyroid21.65
Tongue16.35
Tonsil12.6
Trachea11.5
TrigeminalGanglion15.1
Uterus12.1
UterusCorpus12.6
WholeBlood12.95
Wholebrain20.15
colon13.95
pineal_day18.52
pineal_night16.22
retina16.775
small_intestine13.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P100326
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.02 ± 0.2
Basal Forebrain8.99 ± 0.19
Basal Part of Pons8.91 ± 0.21
Cerebellar Cortex8.96 ± 0.22
Cerebellar Nuclei8.67 ± 0.28
Claustrum9.13 ± 0.18
Epithalamus8.58 ± 0.31
Frontal Lobe8.97 ± 0.24
Globus Pallidus8.45 ± 0.18
Hypothalamus8.83 ± 0.33
Insula9.05 ± 0.15
Limbic Lobe9.1 ± 0.2
Mesencephalon8.92 ± 0.27
Myelencephalon8.97 ± 0.25
Occipital Lobe9.03 ± 0.17
Parietal Lobe9 ± 0.23
Pontine Tegmentum8.87 ± 0.24
Striatum8.79 ± 0.27
Subthalamus8.8 ± 0.02
Temporal Lobe9.02 ± 0.2
Thalamus8.9 ± 0.23
White Matter8.21 ± 0.34
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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