AutismKB 2.0

Annotation Detail for CAMK4


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Basic Information Top
Gene Symbol:CAMK4 ( CaMK-GR,MGC36771 )
Gene Full Name: calcium/calmodulin-dependent protein kinase IV
Band: 5q22.1
Quick LinksEntrez ID:814; OMIM: 114080; Uniprot ID:KCC4_HUMAN; ENSEMBL ID: ENSG00000152495; HGNC ID: 1464
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal100 / 336030729
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain68 / 110098961
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver3 / 20774314
lung0 / 3369740 
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis14 / 33044242
thymus33 / 81131406
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210349_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte5.75
AdrenalCortex6.4
Adrenalgland5.05
Amygdala6.95
Appendix6.1
AtrioventricularNode6.6
BDCA4+_DentriticCells6.15
Bonemarrow6.1
BronchialEpithelialCells5.6
CD105+_Endothelial5.95
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.2
CD33+_Myeloid7.3
CD34+7.15
CD4+_Tcells8.2
CD56+_NKCells6.8
CD71+_EarlyErythroid5.55
CD8+_Tcells12.95
CardiacMyocytes7.85
Caudatenucleus5.35
Cerebellum4.85
CerebellumPeduncles9.8
CiliaryGanglion6.3
CingulateCortex6.35
Colorectaladenocarcinoma5.85
DorsalRootGanglion4.8
FetalThyroid7.15
Fetalbrain5.85
Fetalliver5.35
Fetallung4.8
GlobusPallidus4.5
Heart7.95
Hypothalamus6.3
Kidney4.95
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.75
Liver8.1
Lung6.25
Lymphnode4.8
Lymphoma_burkitts(Daudi)7.75
Lymphoma_burkitts(Raji)8.55
MedullaOblongata5.45
OccipitalLobe5.15
OlfactoryBulb4.7
Ovary4.05
Pancreas4.85
PancreaticIslet6.35
ParietalLobe6.5
Pituitary6.85
Placenta5.8
Pons5.75
PrefrontalCortex6.9
Prostate6.75
Salivarygland4.7
SkeletalMuscle7.2
Skin4.75
SmoothMuscle6.65
Spinalcord6.65
SubthalamicNucleus5.5
SuperiorCervicalGanglion8.45
TemporalLobe5.5
Testis9.85
TestisGermCell6.6
TestisIntersitial11.95
TestisLeydigCell7.25
TestisSeminiferousTubule5.8
Thalamus6.05
Thymus4.95
Thyroid7.3
Tongue6.35
Tonsil5.8
Trachea4.9
TrigeminalGanglion6.4
Uterus4.7
UterusCorpus5.5
WholeBlood6.2
Wholebrain4.9
colon5.8
pineal_day7.18
pineal_night7.1
retina7.05
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12245_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8 ± 0.55
Basal Forebrain7.42 ± 0.51
Basal Part of Pons7.29 ± 0.42
Cerebellar Cortex7.88 ± 0.22
Cerebellar Nuclei5.81 ± 0.69
Claustrum7.21 ± 0.5
Epithalamus6.4 ± 0.39
Frontal Lobe7.22 ± 0.65
Globus Pallidus5.38 ± 0.73
Hypothalamus6.62 ± 0.63
Insula7.35 ± 0.24
Limbic Lobe7.52 ± 0.72
Mesencephalon6.86 ± 0.73
Myelencephalon7.14 ± 0.61
Occipital Lobe7.14 ± 0.59
Parietal Lobe7.05 ± 0.5
Pontine Tegmentum7.03 ± 0.72
Striatum8.28 ± 0.88
Subthalamus6.23 ± 0.24
Temporal Lobe7.43 ± 0.4
Thalamus7.09 ± 0.42
White Matter4.25 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Camk4CBCerebellum80.72
94.76
Camk4CTXCerebral cortex79.94
74.18
Camk4HIPHippocampal region20.61
32.9
Camk4HPFHippocampal formation36.41
38.94
Camk4HYHypothalamus2.23
1.12
Camk4LSXLateral septal complex12.08
8.48
Camk4MBMidbrain2.15
1.49
Camk4MYMedulla2.73
2.49
Camk4OLFOlfactory bulb49.88
42.34
Camk4PPons2.15
1.1
Camk4PALPallidum13.24
11.66
Camk4RHPRetrohippocampal region55.12
44.86
Camk4sAMYStriatum-like amygdalar nuclei16.99
11.68
Camk4STRStriatum96.56
96.07
Camk4STRdStriatum dorsal region100
100
Camk4STRvStriatum ventral region93.52
93.02
Camk4THThalamus18.45
10.69
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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