AutismKB 2.0

Annotation Detail for GRINL1A


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Basic Information Top
Gene Symbol:GRINL1A ( DKFZp586F1918 )
Gene Full Name: glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
Band: 15q22.1
Quick LinksEntrez ID:81488; OMIM: 606485; Uniprot ID:GCOM1_HUMAN; ENSEMBL ID: ENSG00000137878; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212243_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.45
Adipocyte19
AdrenalCortex16.5
Adrenalgland22.35
Amygdala55.05
Appendix26.95
AtrioventricularNode11.65
BDCA4+_DentriticCells88.15
Bonemarrow16.95
BronchialEpithelialCells16.35
CD105+_Endothelial28.25
CD14+_Monocytes23.95
CD19+_BCells(neg._sel.)111.35
CD33+_Myeloid25.5
CD34+25.3
CD4+_Tcells28.4
CD56+_NKCells126.1
CD71+_EarlyErythroid15.9
CD8+_Tcells19.1
CardiacMyocytes23.55
Caudatenucleus29.15
Cerebellum18.2
CerebellumPeduncles31.35
CiliaryGanglion7.55
CingulateCortex22.45
Colorectaladenocarcinoma20.45
DorsalRootGanglion14.45
FetalThyroid13.25
Fetalbrain53.05
Fetalliver16.4
Fetallung15.75
GlobusPallidus9.3
Heart19.1
Hypothalamus53.6
Kidney17.8
Leukemia_chronicMyelogenousK-56222.15
Leukemia_promyelocytic-HL-6016.5
Leukemialymphoblastic(MOLT-4)24.45
Liver25.85
Lung14.55
Lymphnode16.7
Lymphoma_burkitts(Daudi)20.9
Lymphoma_burkitts(Raji)20.8
MedullaOblongata30.95
OccipitalLobe45.15
OlfactoryBulb13.05
Ovary16.55
Pancreas14.9
PancreaticIslet12.95
ParietalLobe33.9
Pituitary18.25
Placenta18.45
Pons23.65
PrefrontalCortex34.8
Prostate26.7
Salivarygland17.5
SkeletalMuscle36.25
Skin14.85
SmoothMuscle19.25
Spinalcord24.75
SubthalamicNucleus22.5
SuperiorCervicalGanglion35.4
TemporalLobe24.15
Testis16.4
TestisGermCell20.5
TestisIntersitial15.6
TestisLeydigCell18.4
TestisSeminiferousTubule15.75
Thalamus30.95
Thymus11.7
Thyroid34.85
Tongue20.8
Tonsil18.6
Trachea23.3
TrigeminalGanglion20.25
Uterus40.05
UterusCorpus24.7
WholeBlood18.95
Wholebrain18.2
colon27.4
pineal_day59.1
pineal_night70
retina39.625
small_intestine26.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_317_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.52 ± 0.29
Basal Forebrain8.6 ± 0.24
Basal Part of Pons8.2 ± 0.2
Cerebellar Cortex8.2 ± 0.23
Cerebellar Nuclei8.56 ± 0.29
Claustrum8.61 ± 0.44
Epithalamus8.38 ± 0.18
Frontal Lobe8.35 ± 0.32
Globus Pallidus9.22 ± 0.13
Hypothalamus8.47 ± 0.33
Insula8.21 ± 0.24
Limbic Lobe8.53 ± 0.37
Mesencephalon8.68 ± 0.29
Myelencephalon8.48 ± 0.3
Occipital Lobe8.75 ± 0.36
Parietal Lobe8.5 ± 0.31
Pontine Tegmentum8.5 ± 0.25
Striatum8.65 ± 0.33
Subthalamus8.84 ± 0.16
Temporal Lobe8.32 ± 0.28
Thalamus8.49 ± 0.24
White Matter9.26 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Grinl1aOLFOlfactory bulb65.98
39.09
Grinl1asAMYStriatum-like amygdalar nuclei69.84
43.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095406 24 99 122 AQNSDPILDTSSLVPGCSSVDNIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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