AutismKB 2.0

Annotation Detail for MAGED4B


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Basic Information Top
Gene Symbol:MAGED4B ( KIAA1859,MGC3210,MGC88639 )
Gene Full Name: melanoma antigen family D, 4B
Band: Xp11.22
Quick LinksEntrez ID:81557; OMIM: 300765; Uniprot ID:MAGD4_HUMAN; ENSEMBL ID: ENSG00000187243; HGNC ID: 22880
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst15 / 62319240
fetus35 / 56401262
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma19 / 106883177
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal117 / 336030734
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone8 / 71655111
bone marrow2 / 4880140
brain64 / 110098958
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue36 / 215722166
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney4 / 21177718
larynx2 / 2414582
liver0 / 2077430 
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221261_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.9
Adipocyte4.6
AdrenalCortex4.8
Adrenalgland3.95
Amygdala41.45
Appendix4.6
AtrioventricularNode3.4
BDCA4+_DentriticCells5.3
Bonemarrow4.75
BronchialEpithelialCells4.6
CD105+_Endothelial4.8
CD14+_Monocytes4.95
CD19+_BCells(neg._sel.)6.85
CD33+_Myeloid5.95
CD34+6.55
CD4+_Tcells4.9
CD56+_NKCells5.6
CD71+_EarlyErythroid4.4
CD8+_Tcells4.4
CardiacMyocytes22.3
Caudatenucleus23.85
Cerebellum4.8
CerebellumPeduncles5.55
CiliaryGanglion5.55
CingulateCortex10.55
Colorectaladenocarcinoma4.65
DorsalRootGanglion3.65
FetalThyroid4.55
Fetalbrain220.05
Fetalliver4.25
Fetallung4
GlobusPallidus3.8
Heart5.75
Hypothalamus116.6
Kidney3.65
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)13.2
Liver6
Lung5.1
Lymphnode3.9
Lymphoma_burkitts(Daudi)5.95
Lymphoma_burkitts(Raji)6.4
MedullaOblongata4.5
OccipitalLobe17.95
OlfactoryBulb3.7
Ovary3.05
Pancreas3.7
PancreaticIslet5
ParietalLobe5.45
Pituitary37.35
Placenta4.8
Pons7.6
PrefrontalCortex48.45
Prostate6.7
Salivarygland3.75
SkeletalMuscle5.15
Skin3.45
SmoothMuscle40.45
Spinalcord25.05
SubthalamicNucleus5.2
SuperiorCervicalGanglion5.1
TemporalLobe9.05
Testis4
TestisGermCell3.95
TestisIntersitial3.9
TestisLeydigCell4.6
TestisSeminiferousTubule4
Thalamus26.8
Thymus3.7
Thyroid5.85
Tongue4.45
Tonsil4.45
Trachea3.9
TrigeminalGanglion4.45
Uterus7.85
UterusCorpus4.6
WholeBlood5.1
Wholebrain27.95
colon4.7
pineal_day5.94
pineal_night6.36
retina5.7
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_4699_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.26 ± 0.34
Basal Forebrain6.51 ± 0.39
Basal Part of Pons6.16 ± 0.51
Cerebellar Cortex5.86 ± 0.55
Cerebellar Nuclei5.1 ± 0.58
Claustrum5.81 ± 0.54
Epithalamus6.36 ± 0.69
Frontal Lobe6.18 ± 0.53
Globus Pallidus6.22 ± 0.47
Hypothalamus7.41 ± 0.49
Insula6.58 ± 0.41
Limbic Lobe6.11 ± 0.53
Mesencephalon6.04 ± 0.56
Myelencephalon6.14 ± 0.62
Occipital Lobe5.51 ± 0.57
Parietal Lobe5.87 ± 0.56
Pontine Tegmentum6.05 ± 0.69
Striatum6.02 ± 0.62
Subthalamus5.99 ± 0.39
Temporal Lobe6.39 ± 0.59
Thalamus6 ± 0.58
White Matter5.61 ± 0.28
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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