AutismKB 2.0

Annotation Detail for C1orf21


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:C1orf21 ( PIG13 )
Gene Full Name: chromosome 1 open reading frame 21
Band: 1q25.3
Quick LinksEntrez ID:81563; OMIM: NA; Uniprot ID:CA021_HUMAN; ENSEMBL ID: ENSG00000116667; HGNC ID: 15494
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus39 / 56401269
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult113 / 193912158
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor20 / 26384575
glioma13 / 106883121
head and neck tumor6 / 13630244
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia8 / 9725082
normal192 / 336030757
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor0 / 902570 
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal3 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone5 / 7165569
bone marrow0 / 488010 
brain66 / 110098959
cervix0 / 481710 
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye13 / 21105461
heart3 / 8962633
intestine12 / 23447251
kidney6 / 21177728
larynx1 / 2414541
liver7 / 20774333
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth3 / 6705244
muscle10 / 10771592
nerve1 / 1576863
ovary3 / 10205129
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate20 / 189345105
salivary gland1 / 2015549
skin19 / 21057490
spleen0 / 539520 
stomach5 / 9661951
testis15 / 33044245
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221272_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.05
Adipocyte4.85
AdrenalCortex5.9
Adrenalgland4.55
Amygdala24.55
Appendix6.75
AtrioventricularNode3.85
BDCA4+_DentriticCells5.2
Bonemarrow5
BronchialEpithelialCells4.6
CD105+_Endothelial4.75
CD14+_Monocytes5
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid6.2
CD34+6.2
CD4+_Tcells4.5
CD56+_NKCells5.85
CD71+_EarlyErythroid4.45
CD8+_Tcells4.4
CardiacMyocytes6.1
Caudatenucleus6.55
Cerebellum16.75
CerebellumPeduncles29.3
CiliaryGanglion4.45
CingulateCortex32.75
Colorectaladenocarcinoma4.95
DorsalRootGanglion4.2
FetalThyroid5.2
Fetalbrain31.1
Fetalliver4.25
Fetallung4.2
GlobusPallidus19.95
Heart6.3
Hypothalamus9.05
Kidney3.95
Leukemia_chronicMyelogenousK-5624.5
Leukemia_promyelocytic-HL-603.9
Leukemialymphoblastic(MOLT-4)4.05
Liver6.65
Lung7.65
Lymphnode4.15
Lymphoma_burkitts(Daudi)6
Lymphoma_burkitts(Raji)6.65
MedullaOblongata21.65
OccipitalLobe48.95
OlfactoryBulb3.6
Ovary3.55
Pancreas4
PancreaticIslet5.8
ParietalLobe36.95
Pituitary5.75
Placenta5.25
Pons11.15
PrefrontalCortex47.65
Prostate5.95
Salivarygland3.85
SkeletalMuscle12.25
Skin3.95
SmoothMuscle5.25
Spinalcord7.45
SubthalamicNucleus11.7
SuperiorCervicalGanglion6.1
TemporalLobe27.05
Testis4.2
TestisGermCell4.5
TestisIntersitial4.1
TestisLeydigCell4.9
TestisSeminiferousTubule6.25
Thalamus18.9
Thymus3.9
Thyroid5.8
Tongue5.1
Tonsil4.65
Trachea4.95
TrigeminalGanglion4.9
Uterus5.35
UterusCorpus5.35
WholeBlood5.55
Wholebrain35.45
colon5
pineal_day6.14
pineal_night6.16
retina6.9
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P151317
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala15.49 ± 0.58
Basal Forebrain15.25 ± 0.15
Basal Part of Pons15.52 ± 0.3
Cerebellar Cortex14.85 ± 0.3
Cerebellar Nuclei15.54 ± 0.24
Claustrum15.41 ± 0.48
Epithalamus14.73 ± 0.34
Frontal Lobe15.28 ± 0.44
Globus Pallidus15.83 ± 0.29
Hypothalamus14.97 ± 0.43
Insula15.07 ± 0.56
Limbic Lobe15.37 ± 0.53
Mesencephalon15.17 ± 0.44
Myelencephalon15.29 ± 0.54
Occipital Lobe15.16 ± 0.63
Parietal Lobe15.17 ± 0.41
Pontine Tegmentum15.1 ± 0.46
Striatum15.55 ± 0.48
Subthalamus15 ± 0.57
Temporal Lobe15.17 ± 0.47
Thalamus15.33 ± 0.51
White Matter15.61 ± 0.29
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018