AutismKB 2.0

Annotation Detail for CLPB


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Basic Information Top
Gene Symbol:CLPB ( FLJ13152,HSP78,SKD3 )
Gene Full Name: ClpB caseinolytic peptidase B homolog (E. coli)
Band: 11q13.4
Quick LinksEntrez ID:81570; OMIM: NA; Uniprot ID:CLPB_HUMAN; ENSEMBL ID: ENSG00000162129; HGNC ID: 30664
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor7 / 11936958
germ cell tumor17 / 26384564
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor0 / 689590 
leukemia19 / 95842198
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal199 / 336030759
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor7 / 12494956
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood17 / 123478137
bone1 / 7165513
bone marrow0 / 488010 
brain40 / 110098936
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine7 / 23447229
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung9 / 33697426
lymph5 / 44270112
lymph node2 / 9161021
mammary gland8 / 15327152
mouth3 / 6705244
muscle7 / 10771564
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate6 / 18934531
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach7 / 9661972
testis149 / 330442450
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221845_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts35.55
Adipocyte14.55
AdrenalCortex16.05
Adrenalgland14.1
Amygdala15.05
Appendix14.85
AtrioventricularNode11.35
BDCA4+_DentriticCells16.05
Bonemarrow15.25
BronchialEpithelialCells14.45
CD105+_Endothelial40.6
CD14+_Monocytes15.65
CD19+_BCells(neg._sel.)14.5
CD33+_Myeloid20.65
CD34+18.35
CD4+_Tcells10.65
CD56+_NKCells14.85
CD71+_EarlyErythroid14.85
CD8+_Tcells13.3
CardiacMyocytes19.75
Caudatenucleus13.5
Cerebellum11.9
CerebellumPeduncles16.75
CiliaryGanglion10.5
CingulateCortex14.95
Colorectaladenocarcinoma22.75
DorsalRootGanglion11.4
FetalThyroid14.15
Fetalbrain15.3
Fetalliver14.85
Fetallung11.85
GlobusPallidus10.85
Heart20.6
Hypothalamus15.8
Kidney12.05
Leukemia_chronicMyelogenousK-56214.05
Leukemia_promyelocytic-HL-6017.55
Leukemialymphoblastic(MOLT-4)11.9
Liver30.7
Lung15.6
Lymphnode12.3
Lymphoma_burkitts(Daudi)18.8
Lymphoma_burkitts(Raji)28.7
MedullaOblongata13.1
OccipitalLobe13.05
OlfactoryBulb11.3
Ovary10.1
Pancreas11.7
PancreaticIslet15.45
ParietalLobe15.7
Pituitary17
Placenta14.2
Pons14
PrefrontalCortex17.4
Prostate16.9
Salivarygland11.75
SkeletalMuscle17.8
Skin11.45
SmoothMuscle18.15
Spinalcord15.2
SubthalamicNucleus13.7
SuperiorCervicalGanglion17.15
TemporalLobe13.3
Testis658.9
TestisGermCell886.9
TestisIntersitial1455.4
TestisLeydigCell228.25
TestisSeminiferousTubule674.4
Thalamus14.8
Thymus11.2
Thyroid18.15
Tongue14.3
Tonsil14.2
Trachea12.3
TrigeminalGanglion14.85
Uterus11.8
UterusCorpus13.25
WholeBlood15.75
Wholebrain12.75
colon14.5
pineal_day18
pineal_night17.96
retina17.95
small_intestine14.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9843_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.46 ± 0.7
Basal Forebrain4.63 ± 0.2
Basal Part of Pons4.69 ± 0.46
Cerebellar Cortex4.31 ± 0.49
Cerebellar Nuclei4.7 ± 0.42
Claustrum4.8 ± 0.59
Epithalamus4.39 ± 0.55
Frontal Lobe4.65 ± 0.44
Globus Pallidus4.41 ± 0.8
Hypothalamus4.48 ± 0.54
Insula4.52 ± 0.45
Limbic Lobe4.33 ± 0.48
Mesencephalon4.46 ± 0.54
Myelencephalon4.52 ± 0.52
Occipital Lobe4.21 ± 0.49
Parietal Lobe4.55 ± 0.43
Pontine Tegmentum4.5 ± 0.59
Striatum4.31 ± 0.43
Subthalamus4.59 ± 0.15
Temporal Lobe4.6 ± 0.51
Thalamus4.59 ± 0.49
White Matter3.89 ± 0.56
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CLPB_HUMAN_409 9 409 417 LDMSEFQER PRIDE
CLPB_HUMAN_547 8 547 554 PILKAHFR PRIDE
CLPB_HUMAN_621 8 621 628 SIKHEVER PRIDE
PAp00002719 15 266 280 GCTALHYAVLADDYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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