AutismKB 2.0

Annotation Detail for CAMK2B


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Basic Information Top
Gene Symbol:CAMK2B ( CAM2,CAMK2,CAMKB,MGC29528 )
Gene Full Name: calcium/calmodulin-dependent protein kinase II beta
Band: 7p13
Quick LinksEntrez ID:816; OMIM: 607707; Uniprot ID:KCC2B_HUMAN; ENSEMBL ID: ENSG00000058404; HGNC ID: 1461
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus47 / 56401283
neonate0 / 310970 
infant5 / 23620211
juvenile3 / 5555653
adult78 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma15 / 106883140
head and neck tumor1 / 1363027
kidney tumor8 / 68959116
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal310 / 336030792
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma4 / 4635686
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain223 / 1100989202
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye18 / 21105485
heart3 / 8962633
intestine0 / 2344720 
kidney8 / 21177737
larynx1 / 2414541
liver1 / 2077434
lung8 / 33697423
lymph0 / 442700 
lymph node11 / 91610120
mammary gland2 / 15327113
mouth0 / 670520 
muscle8 / 10771574
nerve2 / 15768126
ovary0 / 1020510 
pancreas26 / 214812121
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis10 / 33044230
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211483_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte6.15
AdrenalCortex7.1
Adrenalgland5.2
Amygdala178.4
Appendix6.3
AtrioventricularNode5
BDCA4+_DentriticCells6.25
Bonemarrow6.05
BronchialEpithelialCells6.25
CD105+_Endothelial5.7
CD14+_Monocytes6.35
CD19+_BCells(neg._sel.)6.6
CD33+_Myeloid7.5
CD34+7.3
CD4+_Tcells6.15
CD56+_NKCells7.15
CD71+_EarlyErythroid5.8
CD8+_Tcells5.5
CardiacMyocytes9.55
Caudatenucleus99.35
Cerebellum80.15
CerebellumPeduncles693.05
CiliaryGanglion4.35
CingulateCortex181.25
Colorectaladenocarcinoma6.8
DorsalRootGanglion4.75
FetalThyroid7.75
Fetalbrain79.55
Fetalliver5.4
Fetallung5.1
GlobusPallidus77.15
Heart21.75
Hypothalamus46.7
Kidney5.2
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)5.05
Liver8.9
Lung6.95
Lymphnode5.4
Lymphoma_burkitts(Daudi)8.05
Lymphoma_burkitts(Raji)9.1
MedullaOblongata161.2
OccipitalLobe170.8
OlfactoryBulb5.55
Ovary4.15
Pancreas5
PancreaticIslet9.95
ParietalLobe136.5
Pituitary11.45
Placenta6.3
Pons124.3
PrefrontalCortex203.5
Prostate7.45
Salivarygland4.9
SkeletalMuscle17.65
Skin4.7
SmoothMuscle7.1
Spinalcord7.7
SubthalamicNucleus118.45
SuperiorCervicalGanglion7
TemporalLobe77.4
Testis5.45
TestisGermCell5.3
TestisIntersitial5.25
TestisLeydigCell6.25
TestisSeminiferousTubule5.4
Thalamus69.1
Thymus4.85
Thyroid13.2
Tongue7.15
Tonsil6.2
Trachea5.2
TrigeminalGanglion6.1
Uterus6.25
UterusCorpus5.75
WholeBlood6.85
Wholebrain268.5
colon6.2
pineal_day191.88
pineal_night176.36
retina11.525
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10805_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.62 ± 0.76
Basal Forebrain10.73 ± 0.33
Basal Part of Pons10.97 ± 0.42
Cerebellar Cortex10.74 ± 0.23
Cerebellar Nuclei9.55 ± 0.49
Claustrum11.47 ± 0.82
Epithalamus9.63 ± 0.87
Frontal Lobe10.77 ± 0.59
Globus Pallidus9.54 ± 0.73
Hypothalamus10.37 ± 0.63
Insula10.81 ± 0.47
Limbic Lobe11.75 ± 0.81
Mesencephalon10.82 ± 0.82
Myelencephalon11.01 ± 0.74
Occipital Lobe11.91 ± 1.41
Parietal Lobe11.05 ± 0.69
Pontine Tegmentum10.86 ± 0.71
Striatum12.36 ± 0.64
Subthalamus10.32 ± 0.19
Temporal Lobe10.97 ± 0.53
Thalamus11.07 ± 0.52
White Matter8.13 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Camk2bCBCerebellum100
100
Camk2bCTXCerebral cortex100
100
Camk2bHIPHippocampal region100
100
Camk2bHPFHippocampal formation100
100
Camk2bHYHypothalamus100
100
Camk2bLSXLateral septal complex100
100
Camk2bMBMidbrain100
100
Camk2bMYMedulla73.09
100
Camk2bOLFOlfactory bulb100
100
Camk2bPPons73.5
100
Camk2bPALPallidum94.2
100
Camk2bRHPRetrohippocampal region100
100
Camk2bsAMYStriatum-like amygdalar nuclei100
100
Camk2bSTRStriatum100
100
Camk2bSTRdStriatum dorsal region100
100
Camk2bSTRvStriatum ventral region100
100
Camk2bTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025860 25 560 584 ICDPGLTSFEPEALGNLVEGMDFHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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