AutismKB 2.0

Annotation Detail for ADAMTS10


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Basic Information Top
Gene Symbol:ADAMTS10 ( ADAM-TS10,WMS )
Gene Full Name: ADAM metallopeptidase with thrombospondin type 1 motif, 10
Band: 19p13.2
Quick LinksEntrez ID:81794; OMIM: 608990; Uniprot ID:ATS10_HUMAN; ENSEMBL ID: ENSG00000142303; HGNC ID: 13201
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus28 / 56401249
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor7 / 26384526
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal90 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain31 / 110098928
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye5 / 21105423
heart6 / 8962666
intestine3 / 23447212
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen2 / 5395237
stomach1 / 9661910
testis0 / 3304420 
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14179_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.4 ± 0.92
Basal Forebrain1.91 ± 0.28
Basal Part of Pons1.86 ± 0.68
Cerebellar Cortex1.68 ± 0.57
Cerebellar Nuclei2.42 ± 0.89
Claustrum2.84 ± 0.96
Epithalamus1.59 ± 0.95
Frontal Lobe1.76 ± 0.72
Globus Pallidus2.72 ± 0.95
Hypothalamus2.02 ± 0.84
Insula2.34 ± 1.28
Limbic Lobe1.99 ± 0.69
Mesencephalon2.02 ± 0.77
Myelencephalon1.97 ± 0.76
Occipital Lobe1.97 ± 0.75
Parietal Lobe1.96 ± 0.75
Pontine Tegmentum1.96 ± 0.75
Striatum2.03 ± 0.58
Subthalamus2.02 ± 0.71
Temporal Lobe1.83 ± 0.66
Thalamus1.88 ± 0.64
White Matter2.27 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adamts10CBCerebellum3.81
4.53
Adamts10CTXCerebral cortex2.28
1.89
Adamts10HIPHippocampal region1.31
1.41
Adamts10HPFHippocampal formation1.22
1.33
Adamts10HYHypothalamus0.83
0.85
Adamts10LSXLateral septal complex0.43
0.47
Adamts10MBMidbrain2.18
2.17
Adamts10MYMedulla2.44
2.43
Adamts10OLFOlfactory bulb2.91
3.68
Adamts10PPons2.48
2.27
Adamts10PALPallidum1.26
1.19
Adamts10RHPRetrohippocampal region1.06
1.23
Adamts10sAMYStriatum-like amygdalar nuclei1.24
1.08
Adamts10STRStriatum0.92
0.99
Adamts10STRdStriatum dorsal region0.85
0.99
Adamts10STRvStriatum ventral region1.24
1.15
Adamts10THThalamus1.12
1.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018