AutismKB 2.0

Annotation Detail for VANGL1


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Basic Information Top
Gene Symbol:VANGL1 ( KITENIN,LPP2,MGC5338,STB2,STBM2 )
Gene Full Name: vang-like 1 (van gogh, Drosophila)
Band: 1p13.1
Quick LinksEntrez ID:81839; OMIM: 610132; Uniprot ID:VANG1_HUMAN; ENSEMBL ID: ENSG00000173218; HGNC ID: 15512
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus28 / 56401249
neonate1 / 3109732
infant0 / 236200 
juvenile7 / 55556125
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal82 / 336030724
ovarian tumor6 / 7668278
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor8 / 12494964
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites1 / 4001524
bladder1 / 2975733
blood5 / 12347840
bone8 / 71655111
bone marrow2 / 4880140
brain11 / 11009899
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye7 / 21105433
heart8 / 8962689
intestine6 / 23447225
kidney11 / 21177751
larynx0 / 241450 
liver6 / 20774328
lung11 / 33697432
lymph0 / 442700 
lymph node3 / 9161032
mammary gland10 / 15327165
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary7 / 10205168
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin15 / 21057471
spleen0 / 539520 
stomach3 / 9661931
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219330_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.95
Adipocyte6.05
AdrenalCortex6.6
Adrenalgland5.4
Amygdala6.1
Appendix6.9
AtrioventricularNode5.55
BDCA4+_DentriticCells6.4
Bonemarrow6.15
BronchialEpithelialCells11
CD105+_Endothelial20.35
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.3
CD33+_Myeloid8.5
CD34+21.05
CD4+_Tcells6.35
CD56+_NKCells8.15
CD71+_EarlyErythroid6.5
CD8+_Tcells5.65
CardiacMyocytes8.95
Caudatenucleus5.4
Cerebellum5
CerebellumPeduncles6.95
CiliaryGanglion4.6
CingulateCortex6.3
Colorectaladenocarcinoma9.85
DorsalRootGanglion5.1
FetalThyroid5.95
Fetalbrain5.95
Fetalliver8.45
Fetallung4.8
GlobusPallidus4.55
Heart8.7
Hypothalamus6.2
Kidney5.65
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)14.75
Liver9.05
Lung6.7
Lymphnode5
Lymphoma_burkitts(Daudi)7.7
Lymphoma_burkitts(Raji)8.9
MedullaOblongata5.45
OccipitalLobe5.35
OlfactoryBulb4.75
Ovary4.15
Pancreas5
PancreaticIslet6.4
ParietalLobe6.55
Pituitary7
Placenta5.9
Pons5.85
PrefrontalCortex7.4
Prostate7.3
Salivarygland4.95
SkeletalMuscle8.55
Skin7.55
SmoothMuscle6.9
Spinalcord6.45
SubthalamicNucleus5.65
SuperiorCervicalGanglion8.2
TemporalLobe5.6
Testis5.15
TestisGermCell5.05
TestisIntersitial5.05
TestisLeydigCell6.35
TestisSeminiferousTubule5.25
Thalamus6.25
Thymus5.4
Thyroid7.55
Tongue6.95
Tonsil5.95
Trachea5.15
TrigeminalGanglion6.9
Uterus5.15
UterusCorpus5.8
WholeBlood6.5
Wholebrain4.8
colon6.6
pineal_day13.14
pineal_night9.74
retina9.1
small_intestine6.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P103795
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.81 ± 0.8
Basal Forebrain2.76 ± 0.51
Basal Part of Pons2.12 ± 0.54
Cerebellar Cortex2.28 ± 0.52
Cerebellar Nuclei2.84 ± 0.58
Claustrum2.66 ± 0.53
Epithalamus4.16 ± 0.71
Frontal Lobe2.88 ± 0.91
Globus Pallidus3.98 ± 0.52
Hypothalamus2.46 ± 0.63
Insula2.92 ± 0.49
Limbic Lobe2.71 ± 0.75
Mesencephalon2.89 ± 0.8
Myelencephalon3.04 ± 0.9
Occipital Lobe3.13 ± 0.91
Parietal Lobe2.88 ± 0.84
Pontine Tegmentum3.11 ± 0.75
Striatum3.96 ± 0.71
Subthalamus2.18 ± 0.59
Temporal Lobe2.84 ± 0.76
Thalamus4.16 ± 0.8
White Matter3.37 ± 1.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Vangl1CBCerebellum1.39
1.47
Vangl1CTXCerebral cortex0.86
1.04
Vangl1HIPHippocampal region0.59
0.85
Vangl1HPFHippocampal formation0.51
0.63
Vangl1HYHypothalamus1.6
1.32
Vangl1LSXLateral septal complex0.35
0.57
Vangl1MBMidbrain0.5
0.61
Vangl1MYMedulla0.6
0.66
Vangl1OLFOlfactory bulb1.43
2.35
Vangl1PPons0.34
0.41
Vangl1PALPallidum0.4
0.39
Vangl1RHPRetrohippocampal region0.36
0.34
Vangl1sAMYStriatum-like amygdalar nuclei0.28
0.7
Vangl1STRStriatum1.11
1.3
Vangl1STRdStriatum dorsal region1.56
1.82
Vangl1STRvStriatum ventral region0.35
0.24
Vangl1THThalamus18.45
13.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039952 16 337 352 DSSHNELYYEEAEHER Peptide Atlas
VANG1_HUMAN_392 12 392 403 EAAQAIFPSMAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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