AutismKB 2.0

Annotation Detail for MED25


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Basic Information Top
Gene Symbol:MED25 ( ACID1,ARC92,CMT2B2,DKFZp434K0512,MGC70671,P78,PTOV2 )
Gene Full Name: mediator complex subunit 25
Band: 19q13.3
Quick LinksEntrez ID:81857; OMIM: 610197; Uniprot ID:MED25_HUMAN; ENSEMBL ID: ENSG00000104973; HGNC ID: 28845
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma9 / 10688384
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor5 / 10312748
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma10 / 46356215
skin tumor2 / 12494916
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain19 / 110098917
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye15 / 21105471
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx2 / 2414582
liver2 / 2077439
lung6 / 33697417
lymph3 / 4427067
lymph node6 / 9161065
mammary gland5 / 15327132
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary0 / 1020510 
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis10 / 33044230
thymus4 / 8113149
thyroid2 / 4747342
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P153510
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.78 ± 0.38
Basal Forebrain4.69 ± 0.34
Basal Part of Pons4.94 ± 0.25
Cerebellar Cortex4.87 ± 0.49
Cerebellar Nuclei4.48 ± 0.42
Claustrum4.9 ± 0.43
Epithalamus5.02 ± 0.46
Frontal Lobe4.7 ± 0.43
Globus Pallidus4.78 ± 0.34
Hypothalamus4.46 ± 0.55
Insula4.6 ± 0.49
Limbic Lobe4.83 ± 0.43
Mesencephalon4.79 ± 0.41
Myelencephalon4.73 ± 0.46
Occipital Lobe4.88 ± 0.43
Parietal Lobe4.71 ± 0.35
Pontine Tegmentum4.62 ± 0.53
Striatum4.47 ± 0.31
Subthalamus4.08 ± 0.06
Temporal Lobe4.75 ± 0.41
Thalamus4.74 ± 0.41
White Matter4.99 ± 0.35
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011493 15 426 440 SLPCQVYVNHGENLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018