AutismKB 2.0

Annotation Detail for NCOA3


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Basic Information Top
Gene Symbol:NCOA3 ( ACTR,AIB-1,AIB1,CAGH16,CTG26,KAT13B,MGC141848,RAC3,SRC-3,SRC3,TNRC14,TNRC16,TRAM-1,bHLHe42,pCIP )
Gene Full Name: nuclear receptor coactivator 3
Band: 20q13.12
Quick LinksEntrez ID:8202; OMIM: 601937; Uniprot ID:NCOA3_HUMAN; ENSEMBL ID: ENSG00000124151; HGNC ID: 7670
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus18 / 56401231
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult157 / 193912180
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor21 / 94178222
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor7 / 17290404
gastrointestinal tumor10 / 11936983
germ cell tumor8 / 26384530
glioma3 / 10688328
head and neck tumor9 / 13630266
kidney tumor2 / 6895929
leukemia11 / 95842114
liver tumor8 / 9635983
lung tumor5 / 10312748
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal158 / 336030747
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites6 / 40015149
bladder0 / 297570 
blood8 / 12347864
bone1 / 7165513
bone marrow2 / 4880140
brain24 / 110098921
cervix4 / 4817183
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus7 / 20209346
eye8 / 21105437
heart4 / 8962644
intestine9 / 23447238
kidney12 / 21177756
larynx2 / 2414582
liver9 / 20774343
lung13 / 33697438
lymph2 / 4427045
lymph node29 / 91610316
mammary gland25 / 153271163
mouth5 / 6705274
muscle8 / 10771574
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta36 / 280825128
prostate4 / 18934521
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach4 / 9661941
testis20 / 33044260
thymus3 / 8113136
thyroid3 / 4747363
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211352_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts111.35
Adipocyte9.7
AdrenalCortex10.95
Adrenalgland8.45
Amygdala10.1
Appendix11.1
AtrioventricularNode8.1
BDCA4+_DentriticCells125.7
Bonemarrow10.2
BronchialEpithelialCells9.25
CD105+_Endothelial9.45
CD14+_Monocytes11.6
CD19+_BCells(neg._sel.)141.85
CD33+_Myeloid49.45
CD34+12.1
CD4+_Tcells45.95
CD56+_NKCells23.45
CD71+_EarlyErythroid9.25
CD8+_Tcells67.25
CardiacMyocytes13.7
Caudatenucleus8.8
Cerebellum7.95
CerebellumPeduncles11.25
CiliaryGanglion7.15
CingulateCortex9.8
Colorectaladenocarcinoma9.65
DorsalRootGanglion7.75
FetalThyroid9.25
Fetalbrain9.55
Fetalliver8.65
Fetallung8.35
GlobusPallidus7.25
Heart16
Hypothalamus9.7
Kidney8.3
Leukemia_chronicMyelogenousK-5628.95
Leukemia_promyelocytic-HL-6027.1
Leukemialymphoblastic(MOLT-4)7.8
Liver13.75
Lung10.1
Lymphnode16.7
Lymphoma_burkitts(Daudi)14.85
Lymphoma_burkitts(Raji)21.55
MedullaOblongata8.85
OccipitalLobe8.7
OlfactoryBulb7.7
Ovary6.65
Pancreas8.05
PancreaticIslet10.55
ParietalLobe10.35
Pituitary11.1
Placenta52.35
Pons9.4
PrefrontalCortex10.05
Prostate11.45
Salivarygland8.05
SkeletalMuscle17.5
Skin7.9
SmoothMuscle10.5
Spinalcord10.5
SubthalamicNucleus8.9
SuperiorCervicalGanglion13.85
TemporalLobe9.2
Testis8.4
TestisGermCell8.1
TestisIntersitial7.95
TestisLeydigCell9.75
TestisSeminiferousTubule8.4
Thalamus10.05
Thymus10.25
Thyroid12.2
Tongue10.1
Tonsil16.9
Trachea8.3
TrigeminalGanglion10.75
Uterus7.8
UterusCorpus9.6
WholeBlood12.45
Wholebrain7.45
colon9.95
pineal_day12.2
pineal_night11.64
retina11.825
small_intestine9.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P120442
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.32 ± 0.83
Basal Forebrain2.93 ± 0.41
Basal Part of Pons3.17 ± 0.62
Cerebellar Cortex3.63 ± 0.38
Cerebellar Nuclei3.15 ± 0.65
Claustrum3.32 ± 0.55
Epithalamus3.56 ± 0.69
Frontal Lobe3.1 ± 0.68
Globus Pallidus2.83 ± 0.47
Hypothalamus2.99 ± 0.55
Insula2.79 ± 0.73
Limbic Lobe2.9 ± 0.65
Mesencephalon3.25 ± 0.61
Myelencephalon3.18 ± 0.6
Occipital Lobe3.69 ± 0.52
Parietal Lobe3.11 ± 0.69
Pontine Tegmentum3.16 ± 0.67
Striatum2.58 ± 0.67
Subthalamus3.14 ± 0.75
Temporal Lobe3.16 ± 0.63
Thalamus3.32 ± 0.64
White Matter3.55 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ncoa3CBCerebellum47.13
60.81
Ncoa3CTXCerebral cortex100
90.86
Ncoa3HIPHippocampal region81.36
100
Ncoa3HPFHippocampal formation89.45
100
Ncoa3HYHypothalamus55.83
42.69
Ncoa3LSXLateral septal complex66.83
50.74
Ncoa3MBMidbrain50.88
45.57
Ncoa3MYMedulla25.18
26.04
Ncoa3OLFOlfactory bulb87.7
74.78
Ncoa3PPons33.07
34.59
Ncoa3PALPallidum58.13
48.33
Ncoa3RHPRetrohippocampal region100
88.98
Ncoa3sAMYStriatum-like amygdalar nuclei67.95
45.63
Ncoa3STRStriatum82.31
58.74
Ncoa3STRdStriatum dorsal region87.05
62.69
Ncoa3STRvStriatum ventral region85.93
59.33
Ncoa3THThalamus83.13
68.56
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NCOA3_HUMAN_2 15 2 16 SGLGENLDPLASDSR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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