AutismKB 2.0

Annotation Detail for CANX


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Basic Information Top
Gene Symbol:CANX ( CNX,FLJ26570,IP90,P90 )
Gene Full Name: calnexin
Band: 5q35.3
Quick LinksEntrez ID:821; OMIM: 114217; Uniprot ID:CALX_HUMAN; ENSEMBL ID: ENSG00000127022; HGNC ID: 1473
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body45 / 70761635
blastocyst29 / 62319465
fetus151 / 564012267
neonate8 / 31097257
infant9 / 23620381
juvenile90 / 555561619
adult662 / 1939121341
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor9 / 12794703
bladder carcinoma2 / 17475114
breast (mammary gland) tumor51 / 94178541
cervical tumor28 / 34366814
chondrosarcoma29 / 82823350
colorectal tumor38 / 114246332
esophageal tumor10 / 17290578
gastrointestinal tumor40 / 119369335
germ cell tumor98 / 263845371
glioma34 / 106883318
head and neck tumor46 / 136302337
kidney tumor28 / 68959406
leukemia28 / 95842292
liver tumor114 / 963591183
lung tumor21 / 103127203
lymphoma14 / 71755195
non-neoplasia19 / 97250195
normal1172 / 3360307348
ovarian tumor29 / 76682378
pancreatic tumor31 / 104616296
primitive neuroectodermal tumor of the CNS21 / 125680167
prostate cancer47 / 102680457
retinoblastoma7 / 46356151
skin tumor44 / 124949352
soft tissue/muscle tissue tumor24 / 125191191
uterine tumor39 / 90257432
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland18 / 33197542
ascites10 / 40015249
bladder16 / 29757537
blood27 / 123478218
bone35 / 71655488
bone marrow16 / 48801327
brain458 / 1100989415
cervix30 / 48171622
connective tissue44 / 149255294
ear6 / 16212370
embryonic tissue101 / 215722468
esophagus12 / 20209593
eye49 / 211054232
heart19 / 89626211
intestine82 / 234472349
kidney70 / 211777330
larynx0 / 241450 
liver148 / 207743712
lung89 / 336974264
lymph5 / 44270112
lymph node46 / 91610502
mammary gland81 / 153271528
mouth29 / 67052432
muscle23 / 107715213
nerve7 / 15768443
ovary34 / 102051333
pancreas62 / 214812288
parathyroid7 / 20539340
pharynx5 / 41328120
pituitary gland7 / 16585422
placenta112 / 280825398
prostate53 / 189345279
salivary gland9 / 20155446
skin80 / 210574379
spleen9 / 53952166
stomach28 / 96619289
testis189 / 330442571
thymus24 / 81131295
thyroid25 / 47473526
tonsil1 / 1699958
trachea113 / 524132155
umbilical cord0 / 136800 
uterus104 / 232878446
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208853_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts790.25
Adipocyte423.65
AdrenalCortex161.45
Adrenalgland111.7
Amygdala198.75
Appendix117.6
AtrioventricularNode118.7
BDCA4+_DentriticCells1073.9
Bonemarrow218.35
BronchialEpithelialCells467.2
CD105+_Endothelial228.5
CD14+_Monocytes393.4
CD19+_BCells(neg._sel.)169.2
CD33+_Myeloid549.8
CD34+572.15
CD4+_Tcells284.05
CD56+_NKCells414.8
CD71+_EarlyErythroid141.35
CD8+_Tcells243.45
CardiacMyocytes571.55
Caudatenucleus136.25
Cerebellum121.05
CerebellumPeduncles220.2
CiliaryGanglion98.6
CingulateCortex129.05
Colorectaladenocarcinoma306.3
DorsalRootGanglion136.85
FetalThyroid141.4
Fetalbrain175.25
Fetalliver246.05
Fetallung194.45
GlobusPallidus128.45
Heart208
Hypothalamus194.35
Kidney153.7
Leukemia_chronicMyelogenousK-562267.9
Leukemia_promyelocytic-HL-60176.1
Leukemialymphoblastic(MOLT-4)163.55
Liver212.95
Lung98.1
Lymphnode113.65
Lymphoma_burkitts(Daudi)251.4
Lymphoma_burkitts(Raji)157.25
MedullaOblongata120.9
OccipitalLobe220.6
OlfactoryBulb141.6
Ovary206.65
Pancreas180.25
PancreaticIslet409.1
ParietalLobe179.2
Pituitary402.45
Placenta719.75
Pons131
PrefrontalCortex195.2
Prostate199.35
Salivarygland234
SkeletalMuscle152.75
Skin64.25
SmoothMuscle497.55
Spinalcord158.3
SubthalamicNucleus169.15
SuperiorCervicalGanglion154.3
TemporalLobe107.5
Testis138.55
TestisGermCell330.3
TestisIntersitial313
TestisLeydigCell270.3
TestisSeminiferousTubule229.5
Thalamus122.5
Thymus119.6
Thyroid239.05
Tongue154.25
Tonsil253.95
Trachea399.9
TrigeminalGanglion118
Uterus168.45
UterusCorpus237
WholeBlood173.25
Wholebrain128.45
colon498.45
pineal_day374.9
pineal_night358.8
retina279.675
small_intestine385.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P345993
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.84 ± 0.57
Basal Forebrain5.66 ± 0.46
Basal Part of Pons4.74 ± 0.62
Cerebellar Cortex4.68 ± 0.41
Cerebellar Nuclei4.48 ± 0.67
Claustrum5.89 ± 0.52
Epithalamus5.64 ± 0.53
Frontal Lobe5.48 ± 0.57
Globus Pallidus4.42 ± 0.94
Hypothalamus5.51 ± 0.63
Insula5.88 ± 0.34
Limbic Lobe5.55 ± 0.68
Mesencephalon5.19 ± 0.6
Myelencephalon5.35 ± 0.61
Occipital Lobe4.78 ± 0.69
Parietal Lobe5.09 ± 0.64
Pontine Tegmentum5.17 ± 0.65
Striatum5.9 ± 0.67
Subthalamus4.97 ± 0.21
Temporal Lobe5.53 ± 0.54
Thalamus4.96 ± 0.48
White Matter3.31 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CanxCBCerebellum100
100
CanxCTXCerebral cortex100
100
CanxHIPHippocampal region100
100
CanxHPFHippocampal formation100
100
CanxHYHypothalamus100
100
CanxLSXLateral septal complex100
100
CanxMBMidbrain100
100
CanxMYMedulla100
100
CanxOLFOlfactory bulb100
100
CanxPPons100
100
CanxPALPallidum100
100
CanxRHPRetrohippocampal region100
100
CanxsAMYStriatum-like amygdalar nuclei100
100
CanxSTRStriatum100
100
CanxSTRdStriatum dorsal region100
100
CanxSTRvStriatum ventral region100
100
CanxTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CALX_HUMAN_0 0 0 0 KIPNPDFFEDLEPFR PRIDE
CALX_HUMAN_100 11 100 110 YDGKWEVEEMK PRIDE
CALX_HUMAN_104 7 104 110 WEVEEMK PRIDE
CALX_HUMAN_170 23 170 192 TPELNLDQFHDKTPYTIMFGPDK PRIDE
CALX_HUMAN_183 11 183 193 TPYTIMFGPDK PRIDE
CALX_HUMAN_274 18 274 291 EIEDPEDRKPEDWDERPK PRIDE
CALX_HUMAN_382 18 382 399 WKPPMIDNPSYQGIWKPR PRIDE
CALX_HUMAN_400 15 400 414 KIPNPDFFEDLEPFR PRIDE
CALX_HUMAN_401 14 401 414 IPNPDFFEDLEPFR PRIDE
CALX_HUMAN_401 15 401 415 KIPNPDFFEDLEPFR PRIDE
CALX_HUMAN_445 13 445 457 IVDDWANDGWGLK PRIDE
CALX_HUMAN_445 14 445 458 IVDDWANDGWGLKK PRIDE
CALX_HUMAN_551 22 551 572 QKSDAEEDGGTVSQEEEDRKPK PRIDE
CALX_HUMAN_553 20 553 572 SDAEEDGGTVSQEEEDRKPK PRIDE
CALX_HUMAN_554 17 554 570 SDAEEDGGTVSQEEEDR PRIDE
CALX_HUMAN_574 12 574 585 AEEDEILNRSPR PRIDE
CALX_HUMAN_61 16 61 76 APVPTGEVYFADSFDR PRIDE
CALX_HUMAN_62 16 62 77 APVPTGEVYFADSFDR PRIDE
CALX_HUMAN_77 10 77 86 GTLSGWILSK PRIDE
PAp00000642 16 62 77 APVPTGEVYFADSFDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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