Annotation Detail for DGCR14
Basic Information Top
| Gene Symbol: | DGCR14 ( DGCR13,DGS-H,DGS-I,DGSH,DGSI,ES2,Es2el ) |
|---|---|
| Gene Full Name: | DiGeorge syndrome critical region gene 14 |
| Band: | 22q11.21|22q11.2 |
| Quick Links | Entrez ID:8220; OMIM: 601755; Uniprot ID:DGC14_HUMAN; ENSEMBL ID: ENSG00000100056; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.694070
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 23 / 564012 | 40 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 7 / 55556 | 125 |  |
| adult | 70 / 1939121 | 36 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 7 / 564012 | 12 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 0 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 13 / 263845 | 49 | |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 11 / 103127 | 106 | |
| lymphoma | 12 / 71755 | 167 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 110 / 3360307 | 32 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 7 / 104616 | 66 | |
| primitive neuroectodermal tumor of the CNS | 41 / 125680 | 326 |  |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 3 / 90257 | 33 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 18 / 3360307 | 5 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 9 / 123478 | 72 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 42 / 1100989 | 38 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 9 / 211054 | 42 | |
| heart | 0 / 89626 | 0 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 25 / 336974 | 74 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 23 / 280825 | 81 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 3 / 20155 | 148 | |
| skin | 5 / 210574 | 23 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 8 / 330442 | 24 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 5 / 89626 | 55 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 10 / 330442 | 30 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204383_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 8.7 | |
| Adipocyte | 4.75 | |
| AdrenalCortex | 4.9 | |
| Adrenalgland | 4 | |
| Amygdala | 5.15 | |
| Appendix | 4.85 | |
| AtrioventricularNode | 3.6 | |
| BDCA4+_DentriticCells | 11.8 | |
| Bonemarrow | 4.7 | |
| BronchialEpithelialCells | 4.8 | |
| CD105+_Endothelial | 9.9 | |
| CD14+_Monocytes | 9.45 | |
| CD19+_BCells(neg._sel.) | 5.7 | |
| CD33+_Myeloid | 8.45 | |
| CD34+ | 7.85 | |
| CD4+_Tcells | 11.45 | |
| CD56+_NKCells | 8.05 | |
| CD71+_EarlyErythroid | 5.25 | |
| CD8+_Tcells | 9 | |
| CardiacMyocytes | 6.05 | |
| Caudatenucleus | 4.35 | |
| Cerebellum | 3.9 | |
| CerebellumPeduncles | 5.35 | |
| CiliaryGanglion | 3.3 | |
| CingulateCortex | 4.8 | |
| Colorectaladenocarcinoma | 5.55 | |
| DorsalRootGanglion | 3.65 | |
| FetalThyroid | 4.7 | |
| Fetalbrain | 4.75 | |
| Fetalliver | 4.1 | |
| Fetallung | 4 | |
| GlobusPallidus | 3.45 | |
| Heart | 6.35 | |
| Hypothalamus | 5.25 | |
| Kidney | 3.8 | |
| Leukemia_chronicMyelogenousK-562 | 30.1 | |
| Leukemia_promyelocytic-HL-60 | 4.25 | |
| Leukemialymphoblastic(MOLT-4) | 3.95 | |
| Liver | 8.5 | |
| Lung | 20.65 | |
| Lymphnode | 4.1 | |
| Lymphoma_burkitts(Daudi) | 6.15 | |
| Lymphoma_burkitts(Raji) | 6.75 | |
| MedullaOblongata | 4.2 | |
| OccipitalLobe | 4.2 | |
| OlfactoryBulb | 3.8 | |
| Ovary | 3.15 | |
| Pancreas | 3.8 | |
| PancreaticIslet | 5.1 | |
| ParietalLobe | 5 | |
| Pituitary | 5.65 | |
| Placenta | 5 | |
| Pons | 4.6 | |
| PrefrontalCortex | 7.3 | |
| Prostate | 8.75 | |
| Salivarygland | 3.85 | |
| SkeletalMuscle | 5.35 | |
| Skin | 3.7 | |
| SmoothMuscle | 5.45 | |
| Spinalcord | 5.2 | |
| SubthalamicNucleus | 4.3 | |
| SuperiorCervicalGanglion | 5.4 | |
| TemporalLobe | 4.3 | |
| Testis | 26.4 | |
| TestisGermCell | 9.15 | |
| TestisIntersitial | 53.65 | |
| TestisLeydigCell | 5.25 | |
| TestisSeminiferousTubule | 12.4 | |
| Thalamus | 4.9 | |
| Thymus | 4.55 | |
| Thyroid | 7.2 | |
| Tongue | 4.5 | |
| Tonsil | 4.6 | |
| Trachea | 3.95 | |
| TrigeminalGanglion | 4.65 | |
| Uterus | 8.95 | |
| UterusCorpus | 4.3 | |
| WholeBlood | 13 | |
| Wholebrain | 5.35 | |
| colon | 4.85 | |
| pineal_day | 6.22 | |
| pineal_night | 6.18 | |
| retina | 7.225 | |
| small_intestine | 4.65 | |
- Probe name: A_23_P40515
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.04 ± 0.97 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.59 ± 0.18 | |
| Basal Part of Pons | 1.39 ± 0.53 | |
| Cerebellar Cortex | 1.49 ± 0.75 | |
| Cerebellar Nuclei | 1.87 ± 0.72 | |
| Claustrum | 2.49 ± 0.87 | |
| Epithalamus | 1.33 ± 0.7 | |
| Frontal Lobe | 1.42 ± 0.56 | |
| Globus Pallidus | 2.2 ± 0.33 | |
| Hypothalamus | 1.7 ± 0.66 | |
| Insula | 1.59 ± 0.53 | |
| Limbic Lobe | 1.59 ± 0.6 | |
| Mesencephalon | 1.76 ± 0.68 | |
| Myelencephalon | 1.63 ± 0.65 | |
| Occipital Lobe | 1.74 ± 0.56 | |
| Parietal Lobe | 1.65 ± 0.76 | |
| Pontine Tegmentum | 1.67 ± 0.67 | |
| Striatum | 1.74 ± 0.47 | |
| Subthalamus | 1.75 ± 0.63 | |
| Temporal Lobe | 1.52 ± 0.67 | |
| Thalamus | 1.58 ± 0.56 | |
| White Matter | 2.11 ± 0.21 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Es2el | CB | Cerebellum | 35.17 | |
| 43.08 | | |||
| Es2el | CTX | Cerebral cortex | 57.18 | |
| 40.56 | | |||
| Es2el | HIP | Hippocampal region | 32.95 | |
| 38.16 | | |||
| Es2el | HPF | Hippocampal formation | 38.51 | |
| 38.22 | | |||
| Es2el | HY | Hypothalamus | 23.84 | |
| 18.14 | | |||
| Es2el | LSX | Lateral septal complex | 25.5 | |
| 19.97 | | |||
| Es2el | MB | Midbrain | 27.3 | |
| 22.38 | | |||
| Es2el | MY | Medulla | 44.22 | |
| 43.79 | | |||
| Es2el | OLF | Olfactory bulb | 60.35 | |
| 48.16 | | |||
| Es2el | P | Pons | 27.36 | |
| 26.24 | | |||
| Es2el | PAL | Pallidum | 28.82 | |
| 22.12 | | |||
| Es2el | RHP | Retrohippocampal region | 50.95 | |
| 40.37 | | |||
| Es2el | sAMY | Striatum-like amygdalar nuclei | 37.72 | |
| 25.86 | | |||
| Es2el | STR | Striatum | 31.2 | |
| 21.49 | | |||
| Es2el | STRd | Striatum dorsal region | 28.24 | |
| 19.36 | | |||
| Es2el | STRv | Striatum ventral region | 42.78 | |
| 27.57 | | |||
| Es2el | TH | Thalamus | 27.83 | |
| 22.7 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| DGC14_HUMAN_243 | 8 | 243 | 250 | QVVHKNTR | PRIDE |
| PAp00079238 | 20 | 430 | 449 | TPASGLQTPTSTPAPGSATR | Peptide Atlas |