AutismKB 2.0

Annotation Detail for ACOX3


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Basic Information Top
Gene Symbol:ACOX3 ( - )
Gene Full Name: acyl-CoA oxidase 3, pristanoyl
Band: 4p16.1
Quick LinksEntrez ID:8310; OMIM: 603402; Uniprot ID:ACOX3_HUMAN; ENSEMBL ID: ENSG00000087008; HGNC ID: 121
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst4 / 6231964
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult69 / 193912135
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor10 / 26384537
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma7 / 7175597
non-neoplasia2 / 9725020
normal119 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder2 / 2975767
blood2 / 12347816
bone1 / 7165513
bone marrow1 / 4880120
brain32 / 110098929
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine8 / 23447234
kidney9 / 21177742
larynx2 / 2414582
liver5 / 20774324
lung7 / 33697420
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth2 / 6705229
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate14 / 18934573
salivary gland0 / 201550 
skin11 / 21057452
spleen4 / 5395274
stomach2 / 9661920
testis7 / 33044221
thymus4 / 8113149
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204241_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.5
Adipocyte4.25
AdrenalCortex4.55
Adrenalgland3.8
Amygdala4.55
Appendix4.35
AtrioventricularNode3.35
BDCA4+_DentriticCells7.75
Bonemarrow4.3
BronchialEpithelialCells4.3
CD105+_Endothelial4.4
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)4.55
CD33+_Myeloid5.55
CD34+6.2
CD4+_Tcells4.7
CD56+_NKCells5.05
CD71+_EarlyErythroid4.05
CD8+_Tcells4.15
CardiacMyocytes5.85
Caudatenucleus3.9
Cerebellum3.5
CerebellumPeduncles4.9
CiliaryGanglion3.1
CingulateCortex4.45
Colorectaladenocarcinoma4.35
DorsalRootGanglion3.4
FetalThyroid4.2
Fetalbrain4.3
Fetalliver3.75
Fetallung3.65
GlobusPallidus3.2
Heart5.9
Hypothalamus4.7
Kidney3.6
Leukemia_chronicMyelogenousK-5623.9
Leukemia_promyelocytic-HL-603.85
Leukemialymphoblastic(MOLT-4)3.45
Liver6.4
Lung4.8
Lymphnode3.7
Lymphoma_burkitts(Daudi)5.45
Lymphoma_burkitts(Raji)6.1
MedullaOblongata3.95
OccipitalLobe3.9
OlfactoryBulb3.4
Ovary2.9
Pancreas3.45
PancreaticIslet4.7
ParietalLobe4.55
Pituitary5
Placenta5.15
Pons4.15
PrefrontalCortex5.35
Prostate5.1
Salivarygland3.45
SkeletalMuscle5.15
Skin3.4
SmoothMuscle5.2
Spinalcord4.6
SubthalamicNucleus3.95
SuperiorCervicalGanglion5.05
TemporalLobe3.95
Testis3.7
TestisGermCell3.5
TestisIntersitial3.6
TestisLeydigCell4.25
TestisSeminiferousTubule3.65
Thalamus4.35
Thymus3.45
Thyroid5.5
Tongue4.4
Tonsil4.15
Trachea3.6
TrigeminalGanglion4.35
Uterus3.55
UterusCorpus3.9
WholeBlood4.65
Wholebrain3.85
colon4.4
pineal_day5.42
pineal_night5.24
retina5.25
small_intestine4.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P316381
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.97 ± 0.23
Basal Forebrain6.24 ± 0.59
Basal Part of Pons5.78 ± 0.25
Cerebellar Cortex5.68 ± 0.22
Cerebellar Nuclei5.59 ± 0.36
Claustrum6.04 ± 0.33
Epithalamus6.17 ± 0.45
Frontal Lobe6.02 ± 0.31
Globus Pallidus5.97 ± 0.37
Hypothalamus5.76 ± 0.35
Insula6.07 ± 0.27
Limbic Lobe6.06 ± 0.25
Mesencephalon5.89 ± 0.36
Myelencephalon5.94 ± 0.33
Occipital Lobe5.76 ± 0.28
Parietal Lobe5.91 ± 0.32
Pontine Tegmentum6 ± 0.33
Striatum5.8 ± 0.37
Subthalamus5.8 ± 0.33
Temporal Lobe6.11 ± 0.28
Thalamus5.88 ± 0.27
White Matter6.44 ± 0.15
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acox3CBCerebellum32.71
52.76
Acox3CTXCerebral cortex57.77
43.02
Acox3HIPHippocampal region31.8
35.4
Acox3HPFHippocampal formation34.99
33.52
Acox3HYHypothalamus8.65
7.55
Acox3LSXLateral septal complex4.08
2.41
Acox3MBMidbrain25.41
24.92
Acox3MYMedulla26.18
31.25
Acox3OLFOlfactory bulb39.92
30.86
Acox3PPons33.27
37.94
Acox3PALPallidum21.52
21.85
Acox3RHPRetrohippocampal region39.69
31.03
Acox3sAMYStriatum-like amygdalar nuclei15.94
11.17
Acox3STRStriatum18.18
13.62
Acox3STRdStriatum dorsal region18.89
14.33
Acox3STRvStriatum ventral region19.68
14.55
Acox3THThalamus40.28
36.92
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ACOX3_HUMAN_251 15 251 265 LGQNGLDNGFAMFHK PRIDE
PAp00430485 23 172 194 TTAHYDPATEEFIIHSPDFEAAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018