AutismKB 2.0

Annotation Detail for AXIN1


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Basic Information Top
Gene Symbol:AXIN1 ( AXIN,MGC52315 )
Gene Full Name: axin 1
Band: 16p13.3
Quick LinksEntrez ID:8312; OMIM: 603816; Uniprot ID:AXN1_HUMAN; ENSEMBL ID: ENSG00000103126; HGNC ID: 903
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult52 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor4 / 34366116
chondrosarcoma4 / 8282348
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma7 / 10688365
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia10 / 95842104
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma3 / 7175541
non-neoplasia0 / 972500 
normal61 / 336030718
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood8 / 12347864
bone2 / 7165527
bone marrow1 / 4880120
brain18 / 110098916
cervix7 / 48171145
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine13 / 23447255
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung10 / 33697429
lymph3 / 4427067
lymph node5 / 9161054
mammary gland3 / 15327119
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary3 / 10205129
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland1 / 2015549
skin6 / 21057428
spleen1 / 5395218
stomach4 / 9661941
testis6 / 33044218
thymus0 / 811310 
thyroid4 / 4747384
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus11 / 23287847
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212849_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.2
Adipocyte14.85
AdrenalCortex15.25
Adrenalgland15.5
Amygdala15.2
Appendix15
AtrioventricularNode11.15
BDCA4+_DentriticCells18.5
Bonemarrow14.95
BronchialEpithelialCells15.2
CD105+_Endothelial15.35
CD14+_Monocytes16.35
CD19+_BCells(neg._sel.)37.6
CD33+_Myeloid20.45
CD34+19.85
CD4+_Tcells20.9
CD56+_NKCells257.75
CD71+_EarlyErythroid14.1
CD8+_Tcells16.55
CardiacMyocytes17.95
Caudatenucleus13.6
Cerebellum17.25
CerebellumPeduncles17.05
CiliaryGanglion10.35
CingulateCortex15.45
Colorectaladenocarcinoma15.25
DorsalRootGanglion11.2
FetalThyroid14.7
Fetalbrain16.85
Fetalliver13
Fetallung12.5
GlobusPallidus10.85
Heart18.75
Hypothalamus16
Kidney12.05
Leukemia_chronicMyelogenousK-56221.8
Leukemia_promyelocytic-HL-6021.95
Leukemialymphoblastic(MOLT-4)12.8
Liver19.6
Lung21.6
Lymphnode13.25
Lymphoma_burkitts(Daudi)26
Lymphoma_burkitts(Raji)21.55
MedullaOblongata14.1
OccipitalLobe13.35
OlfactoryBulb12.05
Ovary9.9
Pancreas12.1
PancreaticIslet17.15
ParietalLobe15.75
Pituitary17.75
Placenta16
Pons14.3
PrefrontalCortex19.3
Prostate18
Salivarygland12.05
SkeletalMuscle16.7
Skin11.3
SmoothMuscle16.35
Spinalcord16.15
SubthalamicNucleus13.6
SuperiorCervicalGanglion16.75
TemporalLobe13.75
Testis13.25
TestisGermCell12.45
TestisIntersitial12.4
TestisLeydigCell14.9
TestisSeminiferousTubule13.1
Thalamus15.35
Thymus12.3
Thyroid18.95
Tongue14.6
Tonsil14.7
Trachea12.25
TrigeminalGanglion14.8
Uterus12.6
UterusCorpus13.25
WholeBlood20.6
Wholebrain13.15
colon15.4
pineal_day18
pineal_night16.02
retina18.6
small_intestine14.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16948_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.59 ± 0.62
Basal Forebrain5.31 ± 0.19
Basal Part of Pons5.02 ± 0.53
Cerebellar Cortex5.16 ± 0.59
Cerebellar Nuclei4.96 ± 0.54
Claustrum6.24 ± 0.62
Epithalamus4.66 ± 0.35
Frontal Lobe4.9 ± 0.61
Globus Pallidus5.72 ± 0.54
Hypothalamus4.54 ± 0.55
Insula4.8 ± 0.56
Limbic Lobe5.37 ± 0.6
Mesencephalon5.13 ± 0.7
Myelencephalon5.13 ± 0.58
Occipital Lobe5.47 ± 0.57
Parietal Lobe5.25 ± 0.7
Pontine Tegmentum5.18 ± 0.69
Striatum5.24 ± 0.57
Subthalamus4.47 ± 0.79
Temporal Lobe5.07 ± 0.59
Thalamus5.01 ± 0.46
White Matter5.73 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Axin1CBCerebellum2.66
2.71
Axin1CTXCerebral cortex1.76
1.28
Axin1HIPHippocampal region6.6
3.9
Axin1HPFHippocampal formation5.15
3.01
Axin1HYHypothalamus1.58
1.01
Axin1LSXLateral septal complex1.1
0.63
Axin1MBMidbrain2.15
1.79
Axin1MYMedulla4.1
4.28
Axin1OLFOlfactory bulb4.99
3.63
Axin1PPons3.07
2.98
Axin1PALPallidum0.94
0.66
Axin1RHPRetrohippocampal region1.56
1.21
Axin1sAMYStriatum-like amygdalar nuclei2.03
1.2
Axin1STRStriatum1.12
0.67
Axin1STRdStriatum dorsal region0.56
0.36
Axin1STRvStriatum ventral region2.63
1.41
Axin1THThalamus3.03
1.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010936 20 418 437 MEEEGEDGDPSSGPPGPCHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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