AutismKB 2.0

Annotation Detail for CDC7


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Basic Information Top
Gene Symbol:CDC7 ( CDC7L1,HsCDC7,Hsk1,MGC117361,MGC126237,MGC126238,huCDC7 )
Gene Full Name: cell division cycle 7 homolog (S. cerevisiae)
Band: 1p22.1
Quick LinksEntrez ID:8317; OMIM: 603311; Uniprot ID:CDC7_HUMAN; ENSEMBL ID: ENSG00000097046; HGNC ID: 1745
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst9 / 62319144
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor11 / 26384541
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone0 / 716550 
bone marrow3 / 4880161
brain40 / 110098936
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue24 / 215722111
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver2 / 2077439
lung4 / 33697411
lymph0 / 442700 
lymph node7 / 9161076
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis21 / 33044263
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204510_at
Cell line Expression level Expression bar
721_B_lymphoblasts73.15
Adipocyte6.25
AdrenalCortex6.8
Adrenalgland5.45
Amygdala8.4
Appendix6.65
AtrioventricularNode5.8
BDCA4+_DentriticCells13.75
Bonemarrow6.5
BronchialEpithelialCells6.3
CD105+_Endothelial130.4
CD14+_Monocytes6.85
CD19+_BCells(neg._sel.)6.75
CD33+_Myeloid8.9
CD34+155.35
CD4+_Tcells9.4
CD56+_NKCells7.75
CD71+_EarlyErythroid77.4
CD8+_Tcells9.45
CardiacMyocytes8.45
Caudatenucleus5.75
Cerebellum5.35
CerebellumPeduncles7.6
CiliaryGanglion4.6
CingulateCortex6.65
Colorectaladenocarcinoma6.55
DorsalRootGanglion5.4
FetalThyroid6.4
Fetalbrain15.55
Fetalliver30.95
Fetallung5.65
GlobusPallidus5.2
Heart8.35
Hypothalamus7.05
Kidney5.3
Leukemia_chronicMyelogenousK-56220.55
Leukemia_promyelocytic-HL-6063.3
Leukemialymphoblastic(MOLT-4)68.35
Liver8.6
Lung6.95
Lymphnode7.15
Lymphoma_burkitts(Daudi)27.85
Lymphoma_burkitts(Raji)10.45
MedullaOblongata5.95
OccipitalLobe6.8
OlfactoryBulb5
Ovary4.75
Pancreas5.25
PancreaticIslet7
ParietalLobe7.05
Pituitary7.65
Placenta6.6
Pons6.2
PrefrontalCortex11.95
Prostate7.45
Salivarygland5.3
SkeletalMuscle7.55
Skin5.05
SmoothMuscle7.3
Spinalcord6.85
SubthalamicNucleus6.1
SuperiorCervicalGanglion7.7
TemporalLobe6
Testis5.65
TestisGermCell23.65
TestisIntersitial7.6
TestisLeydigCell6.65
TestisSeminiferousTubule7.45
Thalamus6.75
Thymus5.1
Thyroid8
Tongue6.4
Tonsil6.35
Trachea5.35
TrigeminalGanglion7.4
Uterus5.2
UterusCorpus5.9
WholeBlood7.25
Wholebrain5.75
colon6.6
pineal_day13
pineal_night12.04
retina7.75
small_intestine6.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P148807
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.98 ± 0.37
Basal Forebrain7.01 ± 0.25
Basal Part of Pons7.23 ± 0.49
Cerebellar Cortex7.47 ± 0.13
Cerebellar Nuclei6.92 ± 0.36
Claustrum7 ± 0.48
Epithalamus7.11 ± 0.8
Frontal Lobe7.15 ± 0.28
Globus Pallidus5.94 ± 0.24
Hypothalamus6.87 ± 0.36
Insula7.22 ± 0.18
Limbic Lobe6.89 ± 0.4
Mesencephalon6.79 ± 0.48
Myelencephalon6.93 ± 0.53
Occipital Lobe6.91 ± 0.56
Parietal Lobe7.15 ± 0.4
Pontine Tegmentum7.03 ± 0.42
Striatum6.31 ± 0.54
Subthalamus7.23 ± 0.23
Temporal Lobe7.14 ± 0.29
Thalamus7.05 ± 0.4
White Matter5.76 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdc7CBCerebellum18.9
17.85
Cdc7CTXCerebral cortex33.07
21.51
Cdc7HIPHippocampal region38.56
40.23
Cdc7HPFHippocampal formation38.2
35.14
Cdc7HYHypothalamus39.32
26.48
Cdc7LSXLateral septal complex24.8
14.87
Cdc7MBMidbrain38.72
30.04
Cdc7MYMedulla33.89
29.09
Cdc7OLFOlfactory bulb43.85
31.5
Cdc7PPons29.02
24.21
Cdc7PALPallidum20.1
13.92
Cdc7RHPRetrohippocampal region37.71
28.67
Cdc7sAMYStriatum-like amygdalar nuclei39.68
24.76
Cdc7STRStriatum13.92
8.56
Cdc7STRdStriatum dorsal region8.48
5.26
Cdc7STRvStriatum ventral region14.36
8.35
Cdc7THThalamus10.49
7.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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