Annotation Detail for CDC45
Basic Information Top
| Gene Symbol: | CDC45 ( CDC45L,CDC45L2,PORC-PI-1 ) |
|---|---|
| Gene Full Name: | cell division cycle 45 homolog (S. cerevisiae) |
| Band: | 22q11.21 |
| Quick Links | Entrez ID:8318; OMIM: 603465; Uniprot ID:CDC45_HUMAN; ENSEMBL ID: ENSG00000093009; HGNC ID: 1739 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.474217
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 14 / 564012 | 24 | |
| neonate | 0 / 31097 | 0 | |
| infant | 6 / 23620 | 254 |  |
| juvenile | 4 / 55556 | 71 | |
| adult | 27 / 1939121 | 13 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 7 / 114246 | 61 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 9 / 263845 | 34 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 19 / 95842 | 198 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 55 / 3360307 | 16 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 55 / 125680 | 437 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 5 / 46356 | 107 | |
| skin tumor | 13 / 124949 | 104 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 |  |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 0 / 29757 | 0 | |
| blood | 17 / 123478 | 137 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 6 / 48801 | 122 | |
| brain | 14 / 1100989 | 12 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 1 / 89626 | 11 | |
| intestine | 9 / 234472 | 38 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 13 / 207743 | 62 | |
| lung | 2 / 336974 | 5 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 3 / 214812 | 13 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 4 / 189345 | 21 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 13 / 210574 | 61 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 0 / 96619 | 0 | |
| testis | 23 / 330442 | 69 | |
| thymus | 10 / 81131 | 123 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204126_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 76.4 | |
| Adipocyte | 3.95 | |
| AdrenalCortex | 4.3 | |
| Adrenalgland | 3.55 | |
| Amygdala | 4.2 | |
| Appendix | 3.95 | |
| AtrioventricularNode | 3 | |
| BDCA4+_DentriticCells | 4.45 | |
| Bonemarrow | 6.75 | |
| BronchialEpithelialCells | 5.75 | |
| CD105+_Endothelial | 44.75 | |
| CD14+_Monocytes | 4.3 | |
| CD19+_BCells(neg._sel.) | 4.25 | |
| CD33+_Myeloid | 5.2 | |
| CD34+ | 44.4 | |
| CD4+_Tcells | 4.4 | |
| CD56+_NKCells | 4.75 | |
| CD71+_EarlyErythroid | 32.6 | |
| CD8+_Tcells | 3.9 | |
| CardiacMyocytes | 5.75 | |
| Caudatenucleus | 3.65 | |
| Cerebellum | 3.3 | |
| CerebellumPeduncles | 4.6 | |
| CiliaryGanglion | 2.8 | |
| CingulateCortex | 4.1 | |
| Colorectaladenocarcinoma | 22.05 | |
| DorsalRootGanglion | 3 | |
| FetalThyroid | 3.9 | |
| Fetalbrain | 4 | |
| Fetalliver | 5.1 | |
| Fetallung | 3.3 | |
| GlobusPallidus | 2.9 | |
| Heart | 5.15 | |
| Hypothalamus | 4.3 | |
| Kidney | 3.25 | |
| Leukemia_chronicMyelogenousK-562 | 124.55 | |
| Leukemia_promyelocytic-HL-60 | 24.85 | |
| Leukemialymphoblastic(MOLT-4) | 110.6 | |
| Liver | 5.4 | |
| Lung | 4.4 | |
| Lymphnode | 3.5 | |
| Lymphoma_burkitts(Daudi) | 54.5 | |
| Lymphoma_burkitts(Raji) | 5.95 | |
| MedullaOblongata | 3.65 | |
| OccipitalLobe | 3.6 | |
| OlfactoryBulb | 3.2 | |
| Ovary | 2.7 | |
| Pancreas | 3.25 | |
| PancreaticIslet | 4.25 | |
| ParietalLobe | 4.3 | |
| Pituitary | 4.7 | |
| Placenta | 4.1 | |
| Pons | 3.85 | |
| PrefrontalCortex | 5 | |
| Prostate | 4.75 | |
| Salivarygland | 3.3 | |
| SkeletalMuscle | 4.6 | |
| Skin | 3 | |
| SmoothMuscle | 4.65 | |
| Spinalcord | 4.3 | |
| SubthalamicNucleus | 3.65 | |
| SuperiorCervicalGanglion | 4.4 | |
| TemporalLobe | 3.75 | |
| Testis | 39.5 | |
| TestisGermCell | 6.85 | |
| TestisIntersitial | 15.75 | |
| TestisLeydigCell | 16.95 | |
| TestisSeminiferousTubule | 15.3 | |
| Thalamus | 4.1 | |
| Thymus | 11.7 | |
| Thyroid | 5.1 | |
| Tongue | 4 | |
| Tonsil | 3.95 | |
| Trachea | 3.4 | |
| TrigeminalGanglion | 4.2 | |
| Uterus | 3.35 | |
| UterusCorpus | 3.5 | |
| WholeBlood | 4.4 | |
| Wholebrain | 3.35 | |
| colon | 4.05 | |
| pineal_day | 5 | |
| pineal_night | 4.9 | |
| retina | 4.875 | |
| small_intestine | 4 | |
- Probe name: CUST_14491_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.39 ± 1.04 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.97 ± 0.21 | |
| Basal Part of Pons | 1.59 ± 0.35 | |
| Cerebellar Cortex | 1.73 ± 0.67 | |
| Cerebellar Nuclei | 2.23 ± 0.71 | |
| Claustrum | 2.85 ± 0.87 | |
| Epithalamus | 1.63 ± 0.68 | |
| Frontal Lobe | 1.78 ± 0.62 | |
| Globus Pallidus | 2.45 ± 0.27 | |
| Hypothalamus | 1.99 ± 0.62 | |
| Insula | 1.82 ± 0.57 | |
| Limbic Lobe | 1.89 ± 0.58 | |
| Mesencephalon | 2.13 ± 0.73 | |
| Myelencephalon | 1.95 ± 0.66 | |
| Occipital Lobe | 1.92 ± 0.56 | |
| Parietal Lobe | 1.99 ± 0.84 | |
| Pontine Tegmentum | 1.95 ± 0.67 | |
| Striatum | 2.06 ± 0.49 | |
| Subthalamus | 2.1 ± 0.66 | |
| Temporal Lobe | 1.81 ± 0.64 | |
| Thalamus | 1.87 ± 0.54 | |
| White Matter | 2.31 ± 0.15 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cdc45l | CB | Cerebellum | 3.87 | |
| 5.27 | | |||
| Cdc45l | CTX | Cerebral cortex | 2.95 | |
| 2.81 | | |||
| Cdc45l | HIP | Hippocampal region | 8.5 | |
| 12.23 | | |||
| Cdc45l | HPF | Hippocampal formation | 5.86 | |
| 7.68 | | |||
| Cdc45l | HY | Hypothalamus | 1.63 | |
| 1.75 | | |||
| Cdc45l | LSX | Lateral septal complex | 2.1 | |
| 2.17 | | |||
| Cdc45l | MB | Midbrain | 1.35 | |
| 2.23 | | |||
| Cdc45l | MY | Medulla | 3.02 | |
| 4.4 | | |||
| Cdc45l | OLF | Olfactory bulb | 3.34 | |
| 3.74 | | |||
| Cdc45l | P | Pons | 2.94 | |
| 4.58 | | |||
| Cdc45l | PAL | Pallidum | 0.57 | |
| 0.54 | | |||
| Cdc45l | RHP | Retrohippocampal region | 1.33 | |
| 1.27 | | |||
| Cdc45l | sAMY | Striatum-like amygdalar nuclei | 0.84 | |
| 0.55 | | |||
| Cdc45l | STR | Striatum | 2.13 | |
| 2.86 | | |||
| Cdc45l | STRd | Striatum dorsal region | 2.33 | |
| 3.38 | | |||
| Cdc45l | STRv | Striatum ventral region | 2 | |
| 2.23 | | |||
| Cdc45l | TH | Thalamus | 3.06 | |
| 3.18 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00075161 | 14 | 256 | 269 | NEDEENTLSVDCTR | Peptide Atlas |