Annotation Detail for LRRC48
Basic Information Top
| Gene Symbol: | LRRC48 ( DKFZp586M1120 ) |
|---|---|
| Gene Full Name: | leucine rich repeat containing 48 |
| Band: | 17p11.2 |
| Quick Links | Entrez ID:83450; OMIM: NA; Uniprot ID:LRC48_HUMAN; ENSEMBL ID: ENSG00000171962; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.579264
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 |  |
| adult | 30 / 1939121 | 15 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 1 / 263845 | 3 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 54 / 3360307 | 16 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 15 / 1100989 | 13 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 |  |
| heart | 1 / 89626 | 11 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 1 / 24145 | 41 | |
| liver | 2 / 207743 | 9 | |
| lung | 10 / 336974 | 29 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 15 / 330442 | 45 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 5 / 52413 | 95 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 208140_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 9.9 | |
| Adipocyte | 7.55 | |
| AdrenalCortex | 8 | |
| Adrenalgland | 7.1 | |
| Amygdala | 8.2 | |
| Appendix | 8.1 | |
| AtrioventricularNode | 5.95 | |
| BDCA4+_DentriticCells | 8.1 | |
| Bonemarrow | 7.65 | |
| BronchialEpithelialCells | 7.75 | |
| CD105+_Endothelial | 7.55 | |
| CD14+_Monocytes | 8 | |
| CD19+_BCells(neg._sel.) | 7.95 | |
| CD33+_Myeloid | 9.9 | |
| CD34+ | 9.6 | |
| CD4+_Tcells | 8.2 | |
| CD56+_NKCells | 8.85 | |
| CD71+_EarlyErythroid | 7.35 | |
| CD8+_Tcells | 6.9 | |
| CardiacMyocytes | 10.45 | |
| Caudatenucleus | 7.55 | |
| Cerebellum | 6.3 | |
| CerebellumPeduncles | 8.8 | |
| CiliaryGanglion | 5.7 | |
| CingulateCortex | 8.05 | |
| Colorectaladenocarcinoma | 7.65 | |
| DorsalRootGanglion | 5.8 | |
| FetalThyroid | 7.9 | |
| Fetalbrain | 7.85 | |
| Fetalliver | 6.65 | |
| Fetallung | 6.55 | |
| GlobusPallidus | 5.7 | |
| Heart | 10.15 | |
| Hypothalamus | 8.65 | |
| Kidney | 6.55 | |
| Leukemia_chronicMyelogenousK-562 | 6.65 | |
| Leukemia_promyelocytic-HL-60 | 6.65 | |
| Leukemialymphoblastic(MOLT-4) | 6.15 | |
| Liver | 10.1 | |
| Lung | 8.7 | |
| Lymphnode | 6.95 | |
| Lymphoma_burkitts(Daudi) | 9.65 | |
| Lymphoma_burkitts(Raji) | 10.8 | |
| MedullaOblongata | 7.5 | |
| OccipitalLobe | 7 | |
| OlfactoryBulb | 6.15 | |
| Ovary | 5.05 | |
| Pancreas | 6.2 | |
| PancreaticIslet | 8.15 | |
| ParietalLobe | 11.4 | |
| Pituitary | 13.4 | |
| Placenta | 7.3 | |
| Pons | 9.75 | |
| PrefrontalCortex | 9.4 | |
| Prostate | 8.5 | |
| Salivarygland | 7 | |
| SkeletalMuscle | 14.9 | |
| Skin | 5.85 | |
| SmoothMuscle | 8.65 | |
| Spinalcord | 9.3 | |
| SubthalamicNucleus | 7.05 | |
| SuperiorCervicalGanglion | 9 | |
| TemporalLobe | 8.1 | |
| Testis | 6.75 | |
| TestisGermCell | 7.25 | |
| TestisIntersitial | 10.85 | |
| TestisLeydigCell | 7.9 | |
| TestisSeminiferousTubule | 10.15 | |
| Thalamus | 7.9 | |
| Thymus | 6.05 | |
| Thyroid | 17.55 | |
| Tongue | 7.5 | |
| Tonsil | 7.5 | |
| Trachea | 9.25 | |
| TrigeminalGanglion | 7.65 | |
| Uterus | 8.3 | |
| UterusCorpus | 6.95 | |
| WholeBlood | 8.6 | |
| Wholebrain | 6.05 | |
| colon | 7.65 | |
| pineal_day | 10.62 | |
| pineal_night | 10.3 | |
| retina | 10.55 | |
| small_intestine | 6.95 | |
- Probe name: A_24_P270971
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.97 ± 1.04 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.63 ± 0.65 | |
| Basal Part of Pons | 2.82 ± 0.69 | |
| Cerebellar Cortex | 2.75 ± 0.54 | |
| Cerebellar Nuclei | 2.86 ± 0.67 | |
| Claustrum | 3.13 ± 0.77 | |
| Epithalamus | 6.03 ± 1.17 | |
| Frontal Lobe | 2.5 ± 0.96 | |
| Globus Pallidus | 2.91 ± 0.58 | |
| Hypothalamus | 3.13 ± 0.77 | |
| Insula | 2.82 ± 0.81 | |
| Limbic Lobe | 2.73 ± 0.81 | |
| Mesencephalon | 3.04 ± 0.9 | |
| Myelencephalon | 2.94 ± 1.04 | |
| Occipital Lobe | 3.62 ± 0.88 | |
| Parietal Lobe | 3.04 ± 0.85 | |
| Pontine Tegmentum | 2.67 ± 0.94 | |
| Striatum | 3.57 ± 1.71 | |
| Subthalamus | 2.59 ± 0.62 | |
| Temporal Lobe | 2.68 ± 0.91 | |
| Thalamus | 2.55 ± 0.64 | |
| White Matter | 2.16 ± 0.76 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Lrrc48 | CB | Cerebellum | 18.69 | |
| 22.84 | | |||
| Lrrc48 | CTX | Cerebral cortex | 90.12 | |
| 70.8 | | |||
| Lrrc48 | HIP | Hippocampal region | 48.5 | |
| 54.89 | | |||
| Lrrc48 | HPF | Hippocampal formation | 57.59 | |
| 54.99 | | |||
| Lrrc48 | HY | Hypothalamus | 59.29 | |
| 45.87 | | |||
| Lrrc48 | LSX | Lateral septal complex | 74.94 | |
| 69.51 | | |||
| Lrrc48 | MB | Midbrain | 63.55 | |
| 57.22 | | |||
| Lrrc48 | MY | Medulla | 68.21 | |
| 81.19 | | |||
| Lrrc48 | OLF | Olfactory bulb | 92.02 | |
| 79.41 | | |||
| Lrrc48 | P | Pons | 57.88 | |
| 65.22 | | |||
| Lrrc48 | PAL | Pallidum | 45.29 | |
| 40.14 | | |||
| Lrrc48 | RHP | Retrohippocampal region | 74.18 | |
| 56.2 | | |||
| Lrrc48 | sAMY | Striatum-like amygdalar nuclei | 57.18 | |
| 40.68 | | |||
| Lrrc48 | STR | Striatum | 45.1 | |
| 32.93 | | |||
| Lrrc48 | STRd | Striatum dorsal region | 30.12 | |
| 20.5 | | |||
| Lrrc48 | STRv | Striatum ventral region | 79.43 | |
| 55.75 | | |||
| Lrrc48 | TH | Thalamus | 56.37 | |
| 50.03 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| LRC48_HUMAN_114 | 7 | 114 | 120 | LSLFNNR | PRIDE |