AutismKB 2.0

Annotation Detail for ABHD11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ABHD11 ( WBSCR21 )
Gene Full Name: abhydrolase domain containing 11
Band: 7q11.23
Quick LinksEntrez ID:83451; OMIM: NA; Uniprot ID:ABHDB_HUMAN; ENSEMBL ID: ENSG00000106077; HGNC ID: 16407
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor9 / 26384534
glioma7 / 10688365
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal36 / 336030710
ovarian tumor10 / 76682130
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine10 / 23447242
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph2 / 4427045
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary12 / 102051117
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate8 / 18934542
salivary gland0 / 201550 
skin6 / 21057428
spleen2 / 5395237
stomach24 / 96619248
testis7 / 33044221
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221927_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts24.95
Adipocyte22.05
AdrenalCortex25.2
Adrenalgland28.4
Amygdala23.3
Appendix25.5
AtrioventricularNode23.4
BDCA4+_DentriticCells9.65
Bonemarrow22
BronchialEpithelialCells19.6
CD105+_Endothelial18.05
CD14+_Monocytes23.65
CD19+_BCells(neg._sel.)16.4
CD33+_Myeloid21.3
CD34+22.55
CD4+_Tcells14.7
CD56+_NKCells12.3
CD71+_EarlyErythroid19.2
CD8+_Tcells15
CardiacMyocytes22.95
Caudatenucleus19.5
Cerebellum18
CerebellumPeduncles32.95
CiliaryGanglion17.1
CingulateCortex35.1
Colorectaladenocarcinoma102.5
DorsalRootGanglion19.2
FetalThyroid41.35
Fetalbrain21.95
Fetalliver23.65
Fetallung18.1
GlobusPallidus14.7
Heart34.5
Hypothalamus30.7
Kidney34
Leukemia_chronicMyelogenousK-56222.1
Leukemia_promyelocytic-HL-6021.2
Leukemialymphoblastic(MOLT-4)18.95
Liver30.1
Lung31.55
Lymphnode16.9
Lymphoma_burkitts(Daudi)33.4
Lymphoma_burkitts(Raji)39.85
MedullaOblongata22
OccipitalLobe19.95
OlfactoryBulb14.4
Ovary17.05
Pancreas31.4
PancreaticIslet23.65
ParietalLobe22.75
Pituitary39.85
Placenta40.25
Pons28.95
PrefrontalCortex27.4
Prostate146.7
Salivarygland18
SkeletalMuscle23.4
Skin30.05
SmoothMuscle25
Spinalcord24.3
SubthalamicNucleus19.85
SuperiorCervicalGanglion31
TemporalLobe24.85
Testis20.8
TestisGermCell26.2
TestisIntersitial20.2
TestisLeydigCell22.2
TestisSeminiferousTubule23.25
Thalamus30.35
Thymus17.45
Thyroid82.6
Tongue23.9
Tonsil24.65
Trachea22.3
TrigeminalGanglion30.7
Uterus16.1
UterusCorpus21.65
WholeBlood24.2
Wholebrain21.3
colon44.25
pineal_day15.36
pineal_night17.46
retina24.175
small_intestine22.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11448_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.22 ± 0.63
Basal Forebrain6.16 ± 0.22
Basal Part of Pons6.47 ± 0.34
Cerebellar Cortex5.97 ± 0.35
Cerebellar Nuclei6.38 ± 0.3
Claustrum6.33 ± 0.59
Epithalamus5.8 ± 0.25
Frontal Lobe6.3 ± 0.45
Globus Pallidus6.69 ± 0.26
Hypothalamus5.98 ± 0.26
Insula6.05 ± 0.36
Limbic Lobe6.4 ± 0.48
Mesencephalon6.26 ± 0.44
Myelencephalon6.3 ± 0.48
Occipital Lobe6.24 ± 0.47
Parietal Lobe6.18 ± 0.41
Pontine Tegmentum6.08 ± 0.41
Striatum6.23 ± 0.47
Subthalamus6.12 ± 0.18
Temporal Lobe6.21 ± 0.48
Thalamus6.31 ± 0.4
White Matter6.08 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abhd11CBCerebellum71.8
48.65
Abhd11CTXCerebral cortex57.18
38.11
Abhd11HIPHippocampal region41.49
26.56
Abhd11HPFHippocampal formation50.92
35.23
Abhd11HYHypothalamus51.52
32.52
Abhd11LSXLateral septal complex24.07
12.2
Abhd11MBMidbrain37.59
26.24
Abhd11MYMedulla65.96
59.83
Abhd11OLFOlfactory bulb68.75
41.88
Abhd11PPons56.37
53.23
Abhd11PALPallidum34.92
24.81
Abhd11RHPRetrohippocampal region60.65
49.28
Abhd11sAMYStriatum-like amygdalar nuclei42.97
24.76
Abhd11STRStriatum33.67
18.13
Abhd11STRdStriatum dorsal region31.14
16.61
Abhd11STRvStriatum ventral region45.62
23.93
Abhd11THThalamus24.95
14.19
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ABHDB_HUMAN_0 0 0 0 LLDGEAALPAVVFLHGLFGSK PRIDE
ABHDB_HUMAN_185 10 185 194 AINIADELPR PRIDE
ABHDB_HUMAN_58 21 58 78 LLDGEAALPAVVFLHGLFGSK PRIDE
PAp00132036 21 59 79 LLDGEAALPAVVFLHGLFGSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved