AutismKB 2.0

Annotation Detail for ARHGAP24


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Basic Information Top
Gene Symbol:ARHGAP24 ( DKFZp564B1162,FILGAP,FLJ33877,RC-GAP72,RCGAP72,p73,p73RhoGAP )
Gene Full Name: Rho GTPase activating protein 24
Band: 4q21.23-q21.3
Quick LinksEntrez ID:83478; OMIM: 610586; Uniprot ID:RHG24_HUMAN; ENSEMBL ID: ENSG00000138639; HGNC ID: 25361
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus29 / 56401251
neonate4 / 31097128
infant0 / 236200 
juvenile1 / 5555617
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma5 / 7175569
non-neoplasia3 / 9725030
normal136 / 336030740
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue9 / 14925560
ear2 / 16212123
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart4 / 8962644
intestine2 / 2344728
kidney35 / 211777165
larynx0 / 241450 
liver3 / 20774314
lung9 / 33697426
lymph0 / 442700 
lymph node4 / 9161043
mammary gland6 / 15327139
mouth4 / 6705259
muscle2 / 10771518
nerve1 / 1576863
ovary4 / 10205139
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta7 / 28082524
prostate0 / 1893450 
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach5 / 9661951
testis4 / 33044212
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord3 / 13680219
uterus3 / 23287812
vascular18 / 51780347
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221030_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.5
Adipocyte3.7
AdrenalCortex3.9
Adrenalgland3.2
Amygdala3.95
Appendix4.1
AtrioventricularNode3.05
BDCA4+_DentriticCells4.1
Bonemarrow3.65
BronchialEpithelialCells3.55
CD105+_Endothelial3.8
CD14+_Monocytes4
CD19+_BCells(neg._sel.)3.95
CD33+_Myeloid4.75
CD34+4.7
CD4+_Tcells3.9
CD56+_NKCells4.3
CD71+_EarlyErythroid3.45
CD8+_Tcells3.6
CardiacMyocytes4.7
Caudatenucleus3.35
Cerebellum3
CerebellumPeduncles4.35
CiliaryGanglion2.65
CingulateCortex3.85
Colorectaladenocarcinoma3.7
DorsalRootGanglion3.05
FetalThyroid3.65
Fetalbrain3.7
Fetalliver3.2
Fetallung3.05
GlobusPallidus2.8
Heart4.7
Hypothalamus4.1
Kidney3.2
Leukemia_chronicMyelogenousK-5623.35
Leukemia_promyelocytic-HL-603.3
Leukemialymphoblastic(MOLT-4)3
Liver4.85
Lung4.1
Lymphnode3.25
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.2
MedullaOblongata3.45
OccipitalLobe3.35
OlfactoryBulb2.95
Ovary2.55
Pancreas2.95
PancreaticIslet3.95
ParietalLobe3.9
Pituitary4.35
Placenta3.75
Pons3.6
PrefrontalCortex4.7
Prostate4.4
Salivarygland3
SkeletalMuscle4.45
Skin3.5
SmoothMuscle4.25
Spinalcord3.95
SubthalamicNucleus3.5
SuperiorCervicalGanglion5.6
TemporalLobe3.45
Testis3.2
TestisGermCell3.1
TestisIntersitial3.15
TestisLeydigCell3.65
TestisSeminiferousTubule3.2
Thalamus3.8
Thymus2.9
Thyroid4.7
Tongue3.8
Tonsil3.6
Trachea3.1
TrigeminalGanglion4.15
Uterus3.05
UterusCorpus3.35
WholeBlood4
Wholebrain3.15
colon3.7
pineal_day4.62
pineal_night4.58
retina4.475
small_intestine3.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P388659
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.41 ± 0.7
Basal Forebrain3.29 ± 1.07
Basal Part of Pons4.6 ± 0.15
Cerebellar Cortex2.69 ± 0.58
Cerebellar Nuclei4.05 ± 0.56
Claustrum3.22 ± 0.73
Epithalamus3.08 ± 1.02
Frontal Lobe3.24 ± 0.86
Globus Pallidus5.14 ± 0.56
Hypothalamus3.91 ± 0.51
Insula3.44 ± 0.78
Limbic Lobe3.11 ± 0.79
Mesencephalon3.49 ± 0.76
Myelencephalon3.36 ± 0.87
Occipital Lobe3.72 ± 0.83
Parietal Lobe3.46 ± 0.71
Pontine Tegmentum3.27 ± 0.69
Striatum3.62 ± 0.75
Subthalamus4.39 ± 0.9
Temporal Lobe3.17 ± 0.76
Thalamus3.72 ± 0.8
White Matter2.68 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgap24CBCerebellum1.85
3.4
Arhgap24CTXCerebral cortex3.54
3.03
Arhgap24HIPHippocampal region4.66
4.74
Arhgap24HPFHippocampal formation4.97
4.62
Arhgap24HYHypothalamus13.58
14.06
Arhgap24LSXLateral septal complex0.08
0.05
Arhgap24MBMidbrain4.55
6.25
Arhgap24MYMedulla5.1
9.63
Arhgap24OLFOlfactory bulb15.76
14.71
Arhgap24PPons9.87
15.34
Arhgap24PALPallidum12.83
15.01
Arhgap24RHPRetrohippocampal region5.33
4.37
Arhgap24sAMYStriatum-like amygdalar nuclei20.2
16.68
Arhgap24STRStriatum5
4.66
Arhgap24STRdStriatum dorsal region2.97
3.2
Arhgap24STRvStriatum ventral region4.93
4.19
Arhgap24THThalamus14.82
13.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00043166 13 70 82 VSEHPCNEENPGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018