AutismKB 2.0

Annotation Detail for MFRP


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Basic Information Top
Gene Symbol:MFRP ( DKFZp586B0621,FLJ30570,MCOP5,MGC32938,NNO2,RD6 )
Gene Full Name: membrane frizzled-related protein
Band: 11q23.3
Quick LinksEntrez ID:83552; OMIM: 606227; Uniprot ID:C1QT5_HUMAN; ENSEMBL ID: ENSG00000235718; HGNC ID: 18121
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P98783
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.35 ± 0.62
Basal Forebrain5.16 ± 0.22
Basal Part of Pons5.5 ± 0.27
Cerebellar Cortex5.03 ± 0.45
Cerebellar Nuclei5.27 ± 0.39
Claustrum5.6 ± 0.43
Epithalamus4.7 ± 0.31
Frontal Lobe5.21 ± 0.49
Globus Pallidus5.21 ± 0.37
Hypothalamus4.99 ± 0.26
Insula5.09 ± 0.45
Limbic Lobe5.18 ± 0.4
Mesencephalon5.06 ± 0.42
Myelencephalon5.17 ± 0.42
Occipital Lobe5.02 ± 0.43
Parietal Lobe5.11 ± 0.41
Pontine Tegmentum5.05 ± 0.48
Striatum5.12 ± 0.46
Subthalamus5.37 ± 0.29
Temporal Lobe5.16 ± 0.46
Thalamus5.15 ± 0.33
White Matter4.78 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MfrpCBCerebellum8.8
10.8
MfrpCTXCerebral cortex18.7
14.29
MfrpHIPHippocampal region5.52
5.98
MfrpHPFHippocampal formation4.43
4.23
MfrpHYHypothalamus1
1.07
MfrpLSXLateral septal complex0.91
0.77
MfrpMBMidbrain2.48
2.39
MfrpMYMedulla4.6
7
MfrpOLFOlfactory bulb18.28
14.29
MfrpPPons2.7
2.65
MfrpPALPallidum5.55
4.91
MfrpRHPRetrohippocampal region2.55
1.87
MfrpsAMYStriatum-like amygdalar nuclei23.86
18.27
MfrpSTRStriatum12.61
9.96
MfrpSTRdStriatum dorsal region10.43
8.08
MfrpSTRvStriatum ventral region17.1
13.34
MfrpTHThalamus10.31
9.51
Peptide Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018